Madrigal Pharmaceuticals
Madrigal Pharmaceuticals sponsors 17 registered US clinical trials on ClinicalTrials.gov, 1 of them currently recruiting, and 12 completed. 4 of these trials are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is NASH - Nonalcoholic Steatohepatitis, with 2 trials.
Trial Pipeline
17 total, page 1 of 1
Rezdiffra Pregnancy and Lactation Registry
NCT07541469
Study to Evaluate Resmetirom in Post-Liver Transplant Patients With MASH
NCT07335601
A Phase 3 Study to Evaluate the Effect of Resmetirom on Clinical Outcomes in Patients With Well-compensated NASH Cirrhosis (MAESTRO-NASH-OUTCOMES)
NCT05500222
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
A Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and Fibrosis
NCT03900429
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses (6 Days) of 100 mg Resmetirom in Subjects With Severe Renal Impairment and in Matched Healthy Control Subjects With Normal Renal Function
NCT06397872
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients
NCT04197479
Drug Interaction Study of MGL-3196 With Clopidogrel
NCT04671069
Drug Interaction Study of MGL-3196 With Pioglitazone
NCT04671056
Phase 1 Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Multiple Oral Doses of MGL-3196 in Subjects With Varying Degrees of Hepatic Impairment and Healthy Matched Control Subjects
NCT04643795
Bioavailability Study of MGL-3196 Tablets Compared to Capsules
NCT03413124
Radiolabeled Study to Determine the Mass Balance of [14C] MGL-3196
NCT03220165
Phase 2 Study of MGL-3196 in Patients With Non-Alcoholic Steatohepatitis (NASH)
NCT02912260
Drug Interaction Study of MGL-3196 With Atorvastatin
NCT02749578
Drug Interaction Study of MGL-3196 With Rosuvastatin and Simvastatin
NCT02542969
Ascending Multiple-Dose Study to Evaluate VIA-3196 in Healthy Subjects
NCT01519531
Ascending Single-Dose Study to Evaluate VIA-3196 in Healthy Subjects
NCT01367873
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 2 |
| Phase 3 | 4 |
What the Pipeline for Madrigal Pharmaceuticals Shows
According to the ClinicalTrials.gov registry, Madrigal Pharmaceuticals is linked to 17 US clinical trials across every stage of research activity. Of those, 1 studies are currently recruiting, about 6% of the sponsor's indexed portfolio, and 12 are already marked complete, representing roughly 71% of the total.
The phase mix for Madrigal Pharmaceuticals reports 4 late-stage studies (Phase 3 and Phase 4 combined) and 12 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Madrigal Pharmaceuticals is NASH - Nonalcoholic Steatohepatitis with 2 linked trials, and 6 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.