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Dental Plaque clinical trials
Every US clinical trial registered for Dental Plaque — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
11 US clinical trials · 1 currently recruiting
The research picture
Dental Plaque has 11 registered US clinical trials, 1 of them open to new participants right now — about 9% of the total.
- 1
- recruiting participants now
- 9%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 3
- top sponsor: HALEON
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
HALEON
NCT07255040
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
Procter and Gamble
NCT05594004
Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque
Procter and Gamble
NCT04006483
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06660069
Evaluating the Effect of Tooth Cleaning Devices on Oral Health
Philips Oral Healthcare
NCT01250769
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06933368
Study of the Composition of Dental Plaque
National Institute of Dental and Craniofacial Research (NIDCR)
NCT00001726
Clinical Study to Evaluate the Treatment of Gingivitis of Two Toothpastes
Colgate Palmolive
NCT00762515
Effect of Enzymes on Dental Biofilm Accumulation
Novozymes A/S
NCT05579938
A Study to Investigate the Anti-Plaque Effect of AN0128 Toothpaste
Pfizer
NCT00762151
Dental Office Prevention Strategies for Children
University of Minnesota
NCT02004990
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Dental Plaque Trial Landscape
ClinicalTrials.gov lists 11 US studies indexed under Dental Plaque, and 1 of those are currently open to recruitment — roughly 9% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Dental Plaque shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Dental Plaque is led by HALEON with 3 indexed trials, alongside 7 other organizations in the top contributor list. The list on this page surfaces up to 11 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Dental Plaque?
PlainTrial tracks 11 US clinical trials for Dental Plaque, of which 1 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Dental Plaque?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.