Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06244303 · ClinicalTrials.gov registry record · Phase 3
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
A Phase 3 study of Gingivitis and Plaque, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 3
- Development phase
- 82
- Enrollment target
- 1
- Study location
NCT06244303: Completed Phase 3 study of Gingivitis and Plaque, sponsored by Colgate Palmolive.
NCT06244303 is a Phase 3 study of Gingivitis and Plaque that has completed, run by Colgate Palmolive. The registered enrollment target is 82 participants, below the 233-participant average among 25 other Gingivitis trials with a reported enrollment target (65% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06244303, a Phase 3 study of Gingivitis and Plaque, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 82 participants
- Enrollment target
- 1
- Study location
Study Summary
Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after 1-, 3-, 6-, and 12-weeks of unsupervised product use at home. All subjects will be followed for adverse events throughout the study
Primary Outcome
reductions in dental plaque
Conditions Studied
Interventions
- DRUG manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F)
- DRUG manual toothbrush + Colgate dental cream
Study Locations (1)
California
- Mesa Dental Centre - Costa Mesa
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 82 participants |
| Start Date | 2024-01-22 |
| Est. Completion | 2024-04-16 |
| Phase | Phase 3 |
What the finished NCT06244303 record still lists
NCT06244303 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 82 participants, a relatively small participant target, below the 233-participant average among 25 other Gingivitis trials with a reported enrollment target (65% lower).
The record links to 2 conditions, with Gingivitis appearing as the primary indexed condition, and to 2 interventions - of which manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F) is the first listed.
NCT06244303 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06244303 about?
NCT06244303 is a clinical study titled "Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.". Qualified subjects will be enrolled and randomized to one of the two study groups based on their initial Plaque and Gingivitis scores. Subjects will be instructed to use the products according to the instructions provided. Subjects will return to the dental office for evaluation after 1-, 3-, 6-, an...
What is the current status of trial NCT06244303?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 82 participants. The study started on 2024-01-22. Estimated completion is 2024-04-16.
What conditions does trial NCT06244303 study?
This clinical trial studies the following conditions: Gingivitis, Plaque.
What interventions are being tested in trial NCT06244303?
The interventions under investigation include: manual Tooth Brush + Colgate Total TP (0.454% SnF, 1100 ppm F) (DRUG), manual toothbrush + Colgate dental cream (DRUG).
Who is sponsoring clinical trial NCT06244303?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06244303 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Gingivitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06244303's enrollment target sits among peer trials
82 17th of 25 higher than 9 of 25 other Gingivitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Gingivitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
COMPLETED · Phase 3
-
Imaging-based Assessment of Oral Biofilm and Gingival Health
RECRUITING · NA
-
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
RECRUITING · NA
-
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
RECRUITING · NA
-
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
RECRUITING · NA
-
Variation in Gingival Inflammatory Responses
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03319901 · 82 participants · Phase 1
Venetoclax and Chemotherapy as Frontline Therapy in Older Patients and Patients With Relapsed/Refractory ALL
- NCT03493425 · 82 participants · Phase 2
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
- NCT04105270 · 82 participants · Phase 2
RMT in Combination With Durvalumab + Chemo in Untreated Adenocarcinoma NSCLC. A Randomized Double Blind Phase II Trial
- NCT04428658 · 82 participants · NA
Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI