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NCT07029438 · ClinicalTrials.gov registry record · Phase 4
Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis
A Phase 4 study, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 4
- Development phase
- 228
- Enrollment target
NCT07029438: Completed Phase 4 study, sponsored by Colgate Palmolive.
NCT07029438 is a Phase 4 study that has completed, run by Colgate Palmolive. The registered enrollment target is 228 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (56% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07029438, a Phase 4 study, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 228 participants
- Enrollment target
Study Summary
The objective of this clinical research study is to evaluate the efficacy of floss to an essential oil alcohol-containing mouthwash, an essential oil alcohol-free mouthwash, and a CPC+Zn alcohol-free mouthwash in reducing dental plaque and gingivitis.
Primary Outcome
MGI will be visually assessed for six sites for each graded tooth (mesiofacial, facial, distofacial, mesiolingual, lingual, distolingual). Interproximal MGI includes the mesiofacial, distofacial, mesiolingual, and distolingual sites. Higher scores indicate a worse outcome, per below. 0 = no inflammation; no redness 1. = mild inflammation; slight changes in color and texture, but not in all portions of gingival marginal or papillary 2. = mild inflammation; slight changes in color and texture in
Interventions
- DEVICE Toothbrush
- DRUG Mouthwash
- DEVICE Floss
- DRUG Toothpaste
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 228 participants |
| Start Date | 2025-07-07 |
| Est. Completion | 2025-10-16 |
| Phase | Phase 4 |
What the finished NCT07029438 record still lists
NCT07029438 is an interventional study that assigns participants to a tested intervention. The registered 228 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (56% lower).
The record links to 0 conditions, and to 4 interventions - of which Toothbrush is the first listed.
NCT07029438 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07029438 about?
NCT07029438 is a clinical study titled "Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis". The objective of this clinical research study is to evaluate the efficacy of floss to an essential oil alcohol-containing mouthwash, an essential oil alcohol-free mouthwash, and a CPC+Zn alcohol-free mouthwash in reducing dental plaque and gingivitis.
What is the current status of trial NCT07029438?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 228 participants. The study started on 2025-07-07. Estimated completion is 2025-10-16.
What interventions are being tested in trial NCT07029438?
The interventions under investigation include: Toothbrush (DEVICE), Mouthwash (DRUG), Floss (DEVICE), Toothpaste (DRUG).
Who is sponsoring clinical trial NCT07029438?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07029438's enrollment target sits among peer trials
228 374th of 2000 higher than 1,625 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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