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NCT02194621 · ClinicalTrials.gov registry record · Phase 4

Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria

A Phase 4 study, sponsored by Colgate Palmolive.

Completed
Registry status
Phase 4
Development phase
128
Enrollment target

NCT02194621 is a Phase 4 study that has completed, run by Colgate Palmolive. The registered enrollment target is 128 participants.

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The verdict

NCT02194621, a Phase 4 study, has completed, sponsored by Colgate Palmolive.

COMPLETED
Registry status
Phase 4
Development phase
128 participants
Enrollment target

Study Summary

The primary objective was to evaluate the antibacterial effects of two toothpastes containing 0.3% triclosan, 2% copolymer and 0.234% sodium fluoride in a silica base as compared to a control regular fluoride toothpaste on anaerobic and malodor bacteria 12 hours after 13 days of product use. A secondary objective was to demonstrate that a toothpaste containing 0.3% triclosan, 2% copolymer, 0.234% sodium fluoride and a flavor with odor-masking ingredients in silica base (Colgate Total Toothpaste-Flavor Option 1) provides a level of antibacterial efficacy that is "equivalent" to a toothpaste containing 0.3% triclosan, 2% copolymer, 0.234% sodium fluoride and a regular flavor in silica base (Colgate Total Toothpaste-Flavor Option 2) after 13 days of product use.

Interventions

  • DRUG Total Flavor option 1
  • DRUG Total Flavor option 2
  • DRUG Placebo toothpaste: Crest Cavity Protection toothpaste

Trial Details

FieldValue
Enrollment Target 128 participants
Start Date 2014-01
Est. Completion 2014-03
Phase Phase 4

Sponsor

Colgate Palmolive

51 total trials

What the Registry Record Tells You About NCT02194621

The ClinicalTrials.gov registry entry for NCT02194621 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Colgate Palmolive, which has 51 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Total Flavor option 1 is the first listed.

NCT02194621 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02194621 about?

NCT02194621 is a clinical study titled "Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria". The primary objective was to evaluate the antibacterial effects of two toothpastes containing 0.3% triclosan, 2% copolymer and 0.234% sodium fluoride in a silica base as compared to a control regular fluoride toothpaste on anaerobic and malodor bacteria 12 hours after 13 days of product use. A secon...

What is the current status of trial NCT02194621?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 128 participants. The study started on 2014-01. Estimated completion is 2014-03.

What interventions are being tested in trial NCT02194621?

The interventions under investigation include: Total Flavor option 1 (DRUG), Total Flavor option 2 (DRUG), Placebo toothpaste: Crest Cavity Protection toothpaste (DRUG).

Who is sponsoring clinical trial NCT02194621?

This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.