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NCT01072188 · ClinicalTrials.gov registry record · Phase 3
Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste
A Phase 3 study of Hypersensitivity, sponsored by Colgate Palmolive.
- Completed
- Registry status
- Phase 3
- Development phase
- 45
- Enrollment target
- 1
- Study location
NCT01072188: Completed Phase 3 study of Hypersensitivity, sponsored by Colgate Palmolive.
NCT01072188 is a Phase 3 study of Hypersensitivity that has completed, run by Colgate Palmolive. The registered enrollment target is 45 participants, below the 179-participant average among 8 other Hypersensitivity trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01072188, a Phase 3 study of Hypersensitivity, has completed, sponsored by Colgate Palmolive.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 45 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this study is to evaluate the clinical efficacy of a prophylaxis paste containing 10% arginine bicarbonate on dentinal hypersensitivity reduction when applied as a pre-procedure to a professional dental cleaning.
Primary Outcome
Units on a scale: Measured with an electronic force sensing probe (Yeaple Probe): 10, 20, 30, 40, up to 50 grams of force are applied to hypersensitive tooth until pain elicited. Grams of force needed to elicit pain are recorded as hypersensitivity score for the tooth. The higher the score, the higher the hypersensitivity.
Conditions Studied
Interventions
- DEVICE Arginine/Calcium Carbonate
- DEVICE Nupro - Fluoride Free
Study Locations (1)
Pennsylvania
- Contract Dental Evaluations - Langhorne
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 45 participants |
| Start Date | 2008-07 |
| Est. Completion | 2008-08 |
| Phase | Phase 3 |
What the finished NCT01072188 record still lists
NCT01072188 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 45 participants, a relatively small participant target, below the 179-participant average among 8 other Hypersensitivity trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Hypersensitivity appearing as the primary indexed condition, and to 2 interventions - of which Arginine/Calcium Carbonate is the first listed.
NCT01072188 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01072188 about?
NCT01072188 is a clinical study titled "Clinical Efficacy of 10% Arginine Bicarbonate Prophylaxis Paste". The objective of this study is to evaluate the clinical efficacy of a prophylaxis paste containing 10% arginine bicarbonate on dentinal hypersensitivity reduction when applied as a pre-procedure to a professional dental cleaning.
What is the current status of trial NCT01072188?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 45 participants. The study started on 2008-07. Estimated completion is 2008-08.
What conditions does trial NCT01072188 study?
This clinical trial studies the following conditions: Hypersensitivity.
What interventions are being tested in trial NCT01072188?
The interventions under investigation include: Arginine/Calcium Carbonate (DEVICE), Nupro - Fluoride Free (DEVICE).
Who is sponsoring clinical trial NCT01072188?
This trial is sponsored by Colgate Palmolive, which has 51 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01072188 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypersensitivity
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01072188's enrollment target sits among peer trials
45 8th of 8 higher than 1 of 8 other Hypersensitivity trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hypersensitivity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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