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Gingivitis: later-stage trial registry
5 of 26 indexed Gingivitis trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #627 of 28,707 conditions by registered trial count.
26 US clinical trials · 5 currently recruiting · #627 of 28,707 conditions by registered trial count
Gingivitis: 26 US clinical trials tracked, 5 recruiting.
Gingivitis is the subject of 26 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Procter and Gamble, running 5 of these trials.
Enrollment posture brief
Registry condition gingivitis
OPEN 5 | RECR 19% | LATE 5 | EARLY 3 | RANK #627 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Colonoscopy (19% recruiting · 21 trials)
Gingivitis lists 5 open slots (19% of 26 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Gingivitis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Gingivitis is recruiting below its size-band peers.
5 of 26 indexed trials (19.2%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Gingivitis research.
Procter and Gamble accounts for 5 of 26 trials (19.2%). 16 distinct sponsors appear on at least one study for this condition label.
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Typical Gingivitis enrolment sits around 97 participants.
Median target enrolment is 97 among the 26 trials that report a genuine target (sentinel values excluded). 14 of those (53.8%) plan for fewer than 100 participants.
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Gingivitis research is mostly interventional.
24 interventional and 2 observational studies make up this index (92.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
26 total, page 1 of 1
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
HALEON
NCT07255040
Imaging-based Assessment of Oral Biofilm and Gingival Health
University of California, Irvine
NCT05470023
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
Children's Hospital Los Angeles
NCT06122805
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
Missouri Department of Health and Senior Services
NCT06890676
Variation in Gingival Inflammatory Responses
University of Washington
NCT05968742
Evaluating Gingivitis and Systemic Biomarkers
Procter and Gamble
NCT06962956
Assessing Gingivitis and Plaque From a Marketed Toothpaste
Procter and Gamble
NCT07158112
Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients
University of Alabama at Birmingham
NCT07164989
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
Procter and Gamble
NCT05594004
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
GlaxoSmithKline
NCT02750943
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06660069
Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque
Johnson & Johnson Consumer Inc. (J&JCI)
NCT04921371
Incentives for Daily Tooth Brushing to Reduce Gingivitis
University of Pennsylvania
NCT02160418
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06933368
Dose-Response Study of Iocide Oral Rinse
Biomedical Development Corporation
NCT01103102
ToothWave Calculus Reduction and Accumulation Prevention Study
Home Skinovations
NCT04596761
Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste
Colgate Palmolive
NCT04033575
ToothWave Plaque and Gingivitis Study
Home Skinovations
NCT03885323
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Colgate Palmolive
NCT06244303
Oral Hygiene Intervention Pilot Study
Leonardo Marchini
NCT02668809
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
Colgate Palmolive
NCT06300866
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Procter and Gamble
NCT07211061
A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice
Procter and Gamble
NCT02543060
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
University of North Carolina, Chapel Hill
NCT02885064
Evaluation of Toothbrush Bristles in Plaque Reduction
Sunstar Americas
NCT04681885
Atlas of Experimental Gingivitis in Humans
University of North Carolina, Chapel Hill
NCT04105569
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Named interventions
Most-linked intervention names on Gingivitis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Gingivitis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Gingivitis page
26 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 5 Gingivitis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Procter and Gamble sponsors the most Gingivitis trials on record, review their full trial history before evaluating a specific study. See Procter and Gamble's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Gingivitis condition card totals 26 registered trials; most-linked intervention Control placebo with no RF; top US site state Indiana. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.