Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Gingivitis
Open-data reference.
26 US clinical trials · 5 currently recruiting
Active & Recent Trials
A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation
HALEON
NCT07255040
Imaging-based Assessment of Oral Biofilm and Gingival Health
University of California, Irvine
NCT05470023
Effectiveness of Dual Light Electric Toothbrush vs. Manual Toothbrush in Orthodontic Patients Undergoing Oral Surgery
Children's Hospital Los Angeles
NCT06122805
Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control
Missouri Department of Health and Senior Services
NCT06890676
Variation in Gingival Inflammatory Responses
University of Washington
NCT05968742
Evaluating Gingivitis and Systemic Biomarkers
Procter and Gamble
NCT06962956
Assessing Gingivitis and Plaque From a Marketed Toothpaste
Procter and Gamble
NCT07158112
Motivational Interviewing to Improve Oral Hygiene in Adolescent Orthodontic Patients
University of Alabama at Birmingham
NCT07164989
A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health
Procter and Gamble
NCT05594004
Potential of Stannous Fluoride Toothpaste to Reduce Gum Disease
GlaxoSmithKline
NCT02750943
A Study to Evaluate the Efficacy of a Stannous Fluoride Toothpaste With a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06660069
Six Week Study of Experimental Mouth Rinses: Effect on Gingivitis and Plaque
Johnson & Johnson Consumer Inc. (J&JCI)
NCT04921371
Incentives for Daily Tooth Brushing to Reduce Gingivitis
University of Pennsylvania
NCT02160418
A Clinical Study to Evaluate the Efficacy of a Cetylpyridinium Chloride Mouthwash in Improving Gingival Health and Reducing Plaque Accumulation
HALEON
NCT06933368
Dose-Response Study of Iocide Oral Rinse
Biomedical Development Corporation
NCT01103102
ToothWave Calculus Reduction and Accumulation Prevention Study
Home Skinovations
NCT04596761
Clinical Investigation of a Toothpaste Containing Stannous Fluoride as Compared to Colgate Fluoride Toothpaste
Colgate Palmolive
NCT04033575
ToothWave Plaque and Gingivitis Study
Home Skinovations
NCT03885323
Clinical Research Study to Assess the Efficacy of Two Brushing Regimens in the Reduction of Established Dental Plaque and Gingivitis.
Colgate Palmolive
NCT06244303
Oral Hygiene Intervention Pilot Study
Leonardo Marchini
NCT02668809
Gingivitis Reduction After Use of 0.45% Stannous Fluoride Toothpaste
Colgate Palmolive
NCT06300866
A Study is to Evaluate a Regimen on Gingivitis Using Traditional and Novel Assessment Methods
Procter and Gamble
NCT07211061
A Pilot Study to Evaluate a Method for Plaque When Comparing Stannous Fluoride Toothpaste to a Regular Dentifrice
Procter and Gamble
NCT02543060
Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors
University of North Carolina, Chapel Hill
NCT02885064
Evaluation of Toothbrush Bristles in Plaque Reduction
Sunstar Americas
NCT04681885
Atlas of Experimental Gingivitis in Humans
University of North Carolina, Chapel Hill
NCT04105569
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 1 |
| Phase 3 | 2 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Gingivitis Trial Landscape
ClinicalTrials.gov lists 26 US studies indexed under Gingivitis, and 5 of those are currently open to recruitment — roughly 19% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Gingivitis shows 5 late-stage studies (Phase 3 and Phase 4 combined) alongside 3 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Gingivitis is led by Procter and Gamble with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Gingivitis?
PlainTrial tracks 26 US clinical trials for Gingivitis, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Gingivitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.