Brigham and Women's Hospital

937 total trials 145 currently recruiting 608 completed

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.

Trial Pipeline

937 total, page 16 of 19

COMPLETED Phase 4

The Efficacy of Diclofenac Gel for Breakthrough Pain and the Neuropathic Components of Pain in Knee Osteoarthritis

NCT01383954

TERMINATED NA

Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion

NCT01383876

COMPLETED

Prediction of Findings From the Ongoing CAROLINA Trial Using Healthcare Database Analyses

NCT03648424

COMPLETED Phase 3

Optimizing Protein Intake in Older Americans With Mobility Limitations

NCT01275365

COMPLETED Phase 2

Sorbent Therapy of the Cutaneous Porphyrias

NCT01422915

COMPLETED

Use and Effectiveness of a Model Integrative Care Clinic in an Academic Hospital: Study 1-Survey

NCT01353560

COMPLETED Phase 3

A Risk Based Approach to Improving Chronic Kidney Disease Management

NCT01203813

COMPLETED Phase 1

Oral OKT3 for the Treatment of Active Ulcerative Colitis

NCT01287195

COMPLETED Phase 4

Oxytocin And Uterotonic Agent Use For Cesarean Delivery

NCT01549223

COMPLETED

Prediction of Outcomes Following Total Knee Replacement

NCT01370421

COMPLETED Phase 3

Blacks and Exacerbations on Long Acting Beta Agonists (LABA) vs. Tiotropium (BELT)

NCT01290874

COMPLETED NA

Multi-Center Medication Reconciliation Quality Improvement Study

NCT01337063

COMPLETED NA

Demonstration of Near Zero Antibiotic Prescribing for Acute Bronchitis

NCT01240174

COMPLETED NA

Sleep Apnea Intervention for Cardiovascular Disease Reduction

NCT01261390

COMPLETED Phase 3

Study of Vitamin D and Uric Acid Lowering on Kidney and Blood Vessel Function

NCT01320722

COMPLETED Phase 4

Integrated Dual Exercise and Lexiscan Positron Emission Tomography: IDEALPET

NCT01109992

COMPLETED NA

Hypoglycemia and the Mineralocorticoid Receptor

NCT01394627

COMPLETED Phase 4

Milnacipran in the Treatment of Widespread, Non-Joint Pain in Rheumatoid Arthritis

NCT01207453

COMPLETED NA

Development of a Sign-Out Tool to Improve Handoffs in Care

NCT01398761

COMPLETED Phase 4

Barbed Suture vs Smooth Suture for Vaginal Cuff Closure

NCT01262573

COMPLETED

Quantification of Human Adipogenesis

NCT01257997

COMPLETED NA

Effects of Intravenous Lidocaine on Endometriosis Pain

NCT01968694

COMPLETED Phase 2

Effects of cKit Inhibition by Imatinib in Patients With Severe Refractory Asthma (KIA)

NCT01097694

COMPLETED NA

Integrating Patient Generated Family Health History From Varied Electronic Health Record (EHR) Entry Portals

NCT00977847

COMPLETED NA

Light Sensitization Study

NCT01327040

COMPLETED NA

An Automatic Notification System for Test Results Finalized After Discharge

NCT01153451

COMPLETED Phase 4

Clinical Trial of a Silver Eluting Dressing System

NCT01229358

COMPLETED Phase 3

Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation

NCT00970489

COMPLETED NA

Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake

NCT01399632

COMPLETED NA

Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain

NCT01351805

COMPLETED NA

VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-3 TriaL

NCT01696435

COMPLETED NA

Positive Airway Pressure for the Treatment of Asthma

NCT01154699

TERMINATED NA

Novel Pathways to Manage Inflammation and Atherosclerosis in Dialysis Patients: Role of Nicotinic Acid

NCT01159054

COMPLETED Phase 3

Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis

NCT01132118

TERMINATED NA

Assessment of Renin Inhibition on Insulin Sensitivity, Diastolic Function and Aortic Compliance

NCT01252238

COMPLETED NA

Improving Glycemic Control on GMS: A Quality Improvement Study

NCT00271700

COMPLETED

Altered Brain GABA and Glutamate in Restless Legs Syndrome

NCT01109537

TERMINATED Phase 4

Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients

NCT01437943

COMPLETED NA

Effect of Eplerenone on Postprandial Inflammatory Response in Healthy Adults

NCT01786551

COMPLETED NA

Vitamin D Supplementation Reduces Renin-Angiotensin System Activity in Obesity

NCT01068418

COMPLETED Phase 2

Heart Biomarker Evaluation in Apnea Treatment

NCT01086800

COMPLETED NA

Risk Evaluation and Education for Alzheimer's Disease (REVEAL) IV

NCT01434667

COMPLETED Phase 4

Effect of Estradiol+Drospirenone Versus Estradiol+MPA on Endothelial Function

NCT01109979

COMPLETED NA

Human Circadian Sensitivity to Very Short Light Pulses

NCT01330992

COMPLETED Phase 2

Diabetes Prevention in Women With a Recent History of Gestational Diabetes Mellitus (GDM)

NCT01158131

COMPLETED NA

Face Transplantation for Treatment of Severe Facial Deformity

NCT01281267

COMPLETED NA

A Brief Intervention to Improve Cost-effective Resource Use Among Medicine Housestaff

NCT01303263

COMPLETED NA

Does Emotional Support Decrease In Vitro Fertilization Stress?

NCT01406028

COMPLETED NA

Melatonin Treatment for Induced Transient Insomnia

NCT00950885

COMPLETED Phase 3

Randomized Trial: Maternal Vitamin D Supplementation to Prevent Childhood Asthma (VDAART)

NCT00920621

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What the Pipeline for Brigham and Women's Hospital Shows

According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.

The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.