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NCT01437943 · ClinicalTrials.gov registry record · Phase 4
Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients
A Phase 4 study, sponsored by Brigham and Women's Hospital.
- Terminated
- Registry status
- Phase 4
- Development phase
- 10
- Enrollment target
NCT01437943: Clinical Trial Phase 4 study, sponsored by Brigham and Women's Hospital.
NCT01437943 is a Phase 4 study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 10 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01437943, a Phase 4 study, was terminated before completion, sponsored by Brigham and Women's Hospital.
- TERMINATED
- Registry status
- Phase 4
- Development phase
- 10 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the effect of a short-term aliskiren treatment on kidney metabolism in patients at high risk for developing kidney dysfunction (i.e. kidney transplanted patients). The study is aimed at evaluating if any effect on kidney metabolism \[using proton MR Spectroscopy(1H-MRS)\] can be detected following a 6 months treatment with aliskiren regardless of its anti-hypertensive role. 1H-MRS can record a larger number of chemical species (up to 40) in the kidney, and monitor changes according to the pathologic state and health of the transplanted kidney.
Primary Outcome
Evaluation of aliskiren on kidney metabolism by P-MR spectroscopy
Interventions
- DRUG Placebo
- DRUG Aliskiren
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2010-04 |
| Est. Completion | 2012-01 |
| Phase | Phase 4 |
Why NCT01437943 stopped before completion
NCT01437943 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01437943 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01437943 about?
NCT01437943 is a clinical study titled "Effect of Short Term Aliskiren Treatment in Kidney Transplant Patients". The purpose of this study is to evaluate the effect of a short-term aliskiren treatment on kidney metabolism in patients at high risk for developing kidney dysfunction (i.e. kidney transplanted patients). The study is aimed at evaluating if any effect on kidney metabolism \[using proton MR Spectrosc...
What is the current status of trial NCT01437943?
This trial is currently terminated. It is a Phase 4 study. The enrollment target is 10 participants. The study started on 2010-04. Estimated completion is 2012-01.
What interventions are being tested in trial NCT01437943?
The interventions under investigation include: Placebo (DRUG), Aliskiren (DRUG).
Who is sponsoring clinical trial NCT01437943?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01437943's enrollment target sits among peer trials
10 1940th of 2000 higher than 33 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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