Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 17 of 19

COMPLETED NA

Evaluation of a Yoga Intervention for Post-Traumatic Stress Disorder

NCT00962403

COMPLETED NA

Substance Abuse Treatment for High Risk Chronic Pain Patients on Opioid Therapy

NCT00988962

COMPLETED NA

Implementing a Comprehensive Handoff Program to Improve Patient Safety

NCT01130987

COMPLETED Phase 3

Trial of Lycopene/Ateronon for Secondary Prevention of Coronary Heart Disease

NCT00939237

TERMINATED Phase 4

A Trial of Intravenous Calcium and Myocardial Diastolic Dysfunction During Separation From Cardiopulmonary Bypass

NCT00955266

COMPLETED Early Phase 1

Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement

NCT01376011

COMPLETED NA

Ear Electro-stimulation for Chronic Pelvic Pain

NCT01345331

COMPLETED NA

Effect of Daily Low Dose Aspirin on Exhaled Inflammatory Mediators in Normal Subjects

NCT00898222

COMPLETED NA

Effects of Daytime Eszopiclone Administration in Shift Workers

NCT00900159

COMPLETED NA

Discharge ALERT: Quality Improvement Initiative

NCT00853463

COMPLETED

Intrathecal Therapy for Chronic Non-Cancer Pain: An Analysis of Its Efficacy

NCT01564069

COMPLETED NA

Fire Fighter Fatigue Management Program: Operation Healthy Sleep

NCT01988129

TERMINATED NA

Patient Rheumatoid Arthritis Social Support Study

NCT01525654

TERMINATED NA

Goal-directed Fluid Resuscitation in Acute Pancreatitis

NCT00853515

COMPLETED Phase 4

BK Treatment Study

NCT01034176

COMPLETED NA

Mineralocorticoid Receptor and Obesity Induced Cardiovascular Complications

NCT01406015

COMPLETED Phase 4

Opioid Treatment for Chronic Low Back Pain and the Impact of Mood Symptoms

NCT01502644

COMPLETED

Diabetes Prevention in Women With a Recent History of Gestational Diabetes (Focus Groups)

NCT01102530

COMPLETED Early Phase 1

The Effect of Eszopiclone on the Arousal Threshold in Sleep Apnea Syndrome

NCT01102270

COMPLETED NA

Flavanol-Rich Cocoa and Cerebral Blood Flow

NCT00825695

COMPLETED Phase 1

Treatment of Bronchial Asthma With Borage and Echium Seed Oils

NCT00806442

COMPLETED NA

Living Well With Rheumatoid Arthritis

NCT00869349

COMPLETED

Characterization of Immunological Profile of Renal Transplant Patients Undergoing Induction Treatment With Thymoglobulin vs. IL-2 Receptor Antagonist Basiliximab

NCT00842699

COMPLETED Phase 4

Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients

NCT01591382

COMPLETED NA

Role of Mineralocorticoid Receptor in Diabetic Cardiovascular Disease

NCT00865124

COMPLETED Phase 4

An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)

NCT01338636

COMPLETED Phase 3

Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging

NCT00729430

COMPLETED Phase 2

Topical Dexamethasone and Tacrolimus for the Treatment of Oral Chronic Graft-Versus-Host Disease

NCT00686855

COMPLETED NA

Evaluation of a Yoga Program in Schools

NCT01348893

TERMINATED

HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy

NCT00709397

TERMINATED NA

The Effects of Different Long-acting Bronchodilator Medications on Asthma Patients With Different Genetic Variations

NCT00706446

COMPLETED NA

Efficacy of the Pre-Admission Medication List (PAML) Builder Reminder Prompts

NCT00657462

TERMINATED Phase 2

Rho Kinase (ROCK) Inhibition in Carotid Atherosclerosis

NCT00670202

COMPLETED Early Phase 1

Modulation of Cerebral Blood Flow Using Iron Chelators

NCT01365104

COMPLETED NA

Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy

NCT00818766

COMPLETED NA

Effect of Amount and Type of Dietary Carbohydrates on Risk for Cardiovascular Heart Disease and Diabetes

NCT00608049

COMPLETED

Cocoa, Polyphenols, and the Kidney in Healthy Subjects and in Subjects With Hypertension and Diabetes Mellitus

NCT00639665

COMPLETED

Caspofungin or Micafungin as Empiric Antifungal Therapy for Persistent Fever and Neutropenia

NCT00723073

COMPLETED NA

How Different Beta-2 Receptor Genotypes Affect an Asthmatic's Response to Regular Salmeterol Treatment

NCT00595361

COMPLETED

Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease

NCT00595114

COMPLETED Phase 3

Evaluating Ways to Improve Medication Use Among People With Osteoporosis

NCT00567294

COMPLETED Phase 1

Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma

NCT00571298

COMPLETED Phase 4

A Randomized Evaluation of First-dollar Coverage for Post-MI Secondary Preventive Therapies

NCT00566774

TERMINATED Phase 2

A Safety/Efficacy Study of Intracoronary Integrilin to Improve Balloon Angioplasty Outcomes for the Treatment of Heart Attacks

NCT00719914

COMPLETED Phase 3

Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome

NCT00723801

COMPLETED Phase 1

Mepolizumab As a Steroid-sparing Treatment Option in the Churg Strauss Syndrome

NCT00527566

COMPLETED NA

Falls - Tailoring Interventions for Patient Safety

NCT00675935

COMPLETED

3 Screen Electronic Alert

NCT00550082

COMPLETED NA

Study of New Antibiotic Regimen for the Treatment of Uncomplicated Cellulitis in Emergency Department Patients

NCT00676130

COMPLETED Phase 4

A Randomized Clinical Trial To Study Losartan On Endothelial Dysfunction and Insulin Resistance In Obese Patients

NCT00675987

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.