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NCT01751971 · ClinicalTrials.gov registry record · NA
Estimating Apnea Phenotypes From Polysomnography: Oxygen
A NA study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 47
- Enrollment target
NCT01751971: Completed NA study, sponsored by Brigham and Women's Hospital.
NCT01751971 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 47 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01751971, a NA study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 47 participants
- Enrollment target
Study Summary
This study seeks to employ advanced methods to estimate the individual factors contributing to sleep apnea from standard recordings made during routine clinical sleep studies. This study focuses on breathing control or "loop gain" as one of the factors contributing to sleep apnea. Increased levels of oxygen in the air is known to make breathing more stable by lowering "loop gain". Here, our goal is to use a new method capable of detecting a reduction in loop gain with oxygen. The investigators also aim to test whether a high loop gain measured at baseline/placebo predicts a greater improvement in sleep apnea with oxygen therapy.
Primary Outcome
Apnea-hypopnea index (AHI) will be compared between oxygen and sham nights. Hypopneas are based on 30% reduction in airflow (no desaturation or arousal criteria). AHI data are exclusive to non-REM supine sleep. The results presented here are for the AHI at each intervention ("per intervention") regardless of the sequence (preferred clinicaltrials.gov format). Please note, however, that the a priori outcome measure was the reduction in AHI with oxygen as a percent of sham values, i.e. (AHI on s
Interventions
- OTHER Sham
- DRUG Inspired oxygen (40%)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 47 participants |
| Start Date | 2012-11 |
| Est. Completion | 2016-07 |
| Phase | NA |
What the finished NCT01751971 record still lists
NCT01751971 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 47 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.
NCT01751971 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01751971 about?
NCT01751971 is a clinical study titled "Estimating Apnea Phenotypes From Polysomnography: Oxygen". This study seeks to employ advanced methods to estimate the individual factors contributing to sleep apnea from standard recordings made during routine clinical sleep studies. This study focuses on breathing control or "loop gain" as one of the factors contributing to sleep apnea. Increased levels o...
What is the current status of trial NCT01751971?
This trial is currently completed. It is a NA study. The enrollment target is 47 participants. The study started on 2012-11. Estimated completion is 2016-07.
What interventions are being tested in trial NCT01751971?
The interventions under investigation include: Sham (OTHER), Inspired oxygen (40%) (DRUG).
Who is sponsoring clinical trial NCT01751971?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01751971's enrollment target sits among peer trials
47 1400th of 2000 higher than 599 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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