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NCT01728974 · ClinicalTrials.gov registry record · NA
Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study A
A NA study, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 26
- Enrollment target
NCT01728974 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 26 participants.
The verdict
NCT01728974, a NA study, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 26 participants
- Enrollment target
Study Summary
In obstructive sleep apnea, the upper airway recurrently closes during sleep. The mechanisms that lead to airway closure are not completely understood. While the airway of some people narrows and airflow decreases during inspiration due to increasing inspiratory effort, others maintain constant airflow throughout inspiration. Airway neuromuscular reflexes may protect against airway narrowing that occurs due to increasing inspiratory effort. To test this hypothesis, the investigators will initially measure airway neuromuscular reflex and inspiratory flow and then attenuate neuromuscular reflex through topical pharyngeal anesthesia to observe the effects on inspiratory flow.
Interventions
- OTHER Pharyngeal topical anesthesia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 26 participants |
| Start Date | 2012-12-08 |
| Est. Completion | 2018-12-26 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01728974
The ClinicalTrials.gov registry entry for NCT01728974 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 26 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Brigham and Women's Hospital, which has 937 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Pharyngeal topical anesthesia is the first listed.
NCT01728974 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01728974 about?
NCT01728974 is a clinical study titled "Mechanisms of Pharyngeal Collapse in Sleep Apnea, Study A". In obstructive sleep apnea, the upper airway recurrently closes during sleep. The mechanisms that lead to airway closure are not completely understood. While the airway of some people narrows and airflow decreases during inspiration due to increasing inspiratory effort, others maintain constant airf...
What is the current status of trial NCT01728974?
This trial is currently completed. It is a NA study. The enrollment target is 26 participants. The study started on 2012-12-08. Estimated completion is 2018-12-26.
What interventions are being tested in trial NCT01728974?
The interventions under investigation include: Pharyngeal topical anesthesia (OTHER).
Who is sponsoring clinical trial NCT01728974?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
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