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NCT01712269 · ClinicalTrials.gov registry record · NA
Assessment of Sleep Apnea and Its Causes Before and After Weight Loss Surgery
A NA study, sponsored by Brigham and Women's Hospital.
- Terminated
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT01712269: Clinical Trial NA study, sponsored by Brigham and Women's Hospital.
NCT01712269 is a NA study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01712269, a NA study, was terminated before completion, sponsored by Brigham and Women's Hospital.
- TERMINATED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
The central aim of this research project is to determine how the ever-growing problem of obesity in the western world contributes to the pathophysiology of obstructive sleep apnea (OSA). To complete this aim, the investigators will determine the impact of obesity on the mechanisms underlying OSA. This will be achieved by making physiological measurements of 4 physiological traits known to cause OSA as well as the patients sleep apnea severity, before and after weight-loss surgery (i.e. bariatric surgery).
Primary Outcome
Our published method estimates 4 important physiological traits causing OSA: 1) pharyngeal anatomy, 2) loop gain, 3) the ability of the upper airway to dilate/stiffen in response to increases in ventilatory drive, and 4) arousal threshold. These variables are measured using a single maneuver in which CPAP is dropped from an optimum to various suboptimum pressures during sleep. Each individual's set of traits is then entered into a physiological model of OSA that graphically illustrates the relat
Interventions
- PROCEDURE Weight-loss (bariatric) surgery
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2012-10 |
| Est. Completion | 2017-01 |
| Phase | NA |
Why NCT01712269 stopped before completion
NCT01712269 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Weight-loss (bariatric) surgery is the first listed.
NCT01712269 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01712269 about?
NCT01712269 is a clinical study titled "Assessment of Sleep Apnea and Its Causes Before and After Weight Loss Surgery". The central aim of this research project is to determine how the ever-growing problem of obesity in the western world contributes to the pathophysiology of obstructive sleep apnea (OSA). To complete this aim, the investigators will determine the impact of obesity on the mechanisms underlying OSA. Th...
What is the current status of trial NCT01712269?
This trial is currently terminated. It is a NA study. The enrollment target is 10 participants. The study started on 2012-10. Estimated completion is 2017-01.
What interventions are being tested in trial NCT01712269?
The interventions under investigation include: Weight-loss (bariatric) surgery (PROCEDURE).
Who is sponsoring clinical trial NCT01712269?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01712269's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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