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NCT02339506 · ClinicalTrials.gov registry record · NA
Stress and the Nervous System
A NA study of Stress, Physiological and Autonomic Nervous System, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT02339506: Completed NA study of Stress, Physiological and Autonomic Nervous System, sponsored by Brigham and Women's Hospital.
NCT02339506 is a NA study of Stress, Physiological and Autonomic Nervous System that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 23 participants, below the 351-participant average among 9 other Stress, Physiological trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02339506, a NA study of Stress, Physiological and Autonomic Nervous System, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
Models of stress such as hypoglycemia have identified that stress results the next day in decreased baroreflex sensitivity. This project will test the hypothesis that these delayed changes in autonomic nervous system function are secondary to a rise in ACTH. The investigators will infuse cosyntropin versus placebo in a double-blind, crossover study in healthy adults and measure the delayed effects on the autonomic system as measured by cardiovagal baroreflex sensitivity.
Primary Outcome
Cardiovagal baroreflex sensitivity will be measured with the Modified Oxford Technique before, during, and after drug infusions, to evaluate the effects of cosyntropin infusions.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Cosyntropin
Study Locations (1)
Massachusetts
- Brigham and Women's Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2015-04 |
| Est. Completion | 2020-11 |
| Phase | NA |
What the finished NCT02339506 record still lists
NCT02339506 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 351-participant average among 9 other Stress, Physiological trials with a reported enrollment target (93% lower).
The record links to 3 conditions, with Stress, Physiological appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02339506 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02339506 about?
NCT02339506 is a clinical study titled "Stress and the Nervous System". Models of stress such as hypoglycemia have identified that stress results the next day in decreased baroreflex sensitivity. This project will test the hypothesis that these delayed changes in autonomic nervous system function are secondary to a rise in ACTH. The investigators will infuse cosyntropin...
What is the current status of trial NCT02339506?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2015-04. Estimated completion is 2020-11.
What conditions does trial NCT02339506 study?
This clinical trial studies the following conditions: Stress, Physiological, Autonomic Nervous System, Baroreflex.
What interventions are being tested in trial NCT02339506?
The interventions under investigation include: Placebo (DRUG), Cosyntropin (DRUG).
Who is sponsoring clinical trial NCT02339506?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02339506 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02339506's enrollment target sits among peer trials
23 9th of 9 higher than 1 of 9 other Stress, Physiological trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stress, Physiological trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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