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NCT02216513 · ClinicalTrials.gov registry record · Early Phase 1

Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

A Early Phase 1 study, sponsored by Brigham and Women's Hospital.

Terminated
Registry status
Early Phase 1
Development phase
2
Enrollment target

NCT02216513: Clinical Trial Early Phase 1 study, sponsored by Brigham and Women's Hospital.

NCT02216513 is a Early Phase 1 study that was terminated before completion, run by Brigham and Women's Hospital. The registered enrollment target is 2 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02216513, a Early Phase 1 study, was terminated before completion, sponsored by Brigham and Women's Hospital.

TERMINATED
Registry status
Early Phase 1
Development phase
2 participants
Enrollment target

Study Summary

The investigators will test the central hypothesis that DFO treatment after SAH may improve cerebrovascular regulation, mitigate ischemic neural injury, and serve as an effective neuroprotectant against delayed ischemic injury after SAH.

Primary Outcome

DCI will be defined radiographically as any cerebral infarct on the latest CT scan that was seen within 6 weeks after SAH or before discharge or death, that was not present on admission scan or on the CT scan done within 24 to 48 hours after any aneurysmal treatment procedures. All head CT scans will be reviewed for DCI ascertainment by neuroradiologists blinded to the clinical and TCD data using the standardized protocol.

Interventions

  • DRUG placebo
  • DRUG desferrioxamine (DFO)

Trial Details

FieldValue
Enrollment Target 2 participants
Start Date 2014-09
Est. Completion 2015-07
Phase Early Phase 1
Brigham and Women's Hospital

937 total trials

Why NCT02216513 stopped before completion

NCT02216513 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which placebo is the first listed.

NCT02216513 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02216513 about?

NCT02216513 is a clinical study titled "Deferoxamine to Prevent Delayed Cerebral Ischemia After Subarachnoid Hemorrhage". The investigators will test the central hypothesis that DFO treatment after SAH may improve cerebrovascular regulation, mitigate ischemic neural injury, and serve as an effective neuroprotectant against delayed ischemic injury after SAH.

What is the current status of trial NCT02216513?

This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 2 participants. The study started on 2014-09. Estimated completion is 2015-07.

What interventions are being tested in trial NCT02216513?

The interventions under investigation include: placebo (DRUG), desferrioxamine (DFO) (DRUG).

Who is sponsoring clinical trial NCT02216513?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02216513's enrollment target sits among peer trials

2 1973rd of 2000 higher than 16 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02216513, the US trial registry maintained by the National Library of Medicine. NCT02216513 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.