Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03637699 · ClinicalTrials.gov registry record · NA

A Positive Psychology Intervention for Patients With Multiple Sclerosis

A NA study, sponsored by Brigham and Women's Hospital.

Completed
Registry status
NA
Development phase
30
Enrollment target

NCT03637699: Completed NA study, sponsored by Brigham and Women's Hospital.

NCT03637699 is a NA study that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03637699, a NA study, has completed, sponsored by Brigham and Women's Hospital.

COMPLETED
Registry status
NA
Development phase
30 participants
Enrollment target

Study Summary

Positive psychology (PP) uses targeted activities to increase the frequency and intensity of positive emotional experiences such as positive affect. Examples of PP activities include recalling positive life events and performing acts of kindness. This pilot study will examine the tolerability and efficacy of a PP training program to increase positive affect in patients with multiple sclerosis (MS). In the intervention phase, subjects randomized to the intervention group will complete five weeks of PP exercises, one exercise per week. Subjects will also have weekly calls with the study trainer. The control group will have no study activities. In the extension phase, subjects in the control group will complete PP training as described above. The investigators will examine the tolerability of the program by calculating the proportion of subjects who complete the program. The investigators will also examine exercise-specific ratings of ease and utility to measure the acceptability of each exercise. Finally, the investigators will evaluate the efficacy of PP training by comparing subjects in the intervention and control groups on measures of positive affect, emotional function, health-related quality of life (HRQOL) and self-reported functional activities such as work. If successful, this study will advance the use of PP as a low cost, innovative and effective tool for increasing positive affect, decreasing depression and anxiety and improving HRQOL in patients with MS.

Primary Outcome

Measured by percentage of PP exercises completed by subjects.

Interventions

  • BEHAVIORAL Positive Psychology

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2018-03-12
Est. Completion 2019-04-09
Phase NA
Brigham and Women's Hospital

937 total trials

What the finished NCT03637699 record still lists

NCT03637699 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Positive Psychology is the first listed.

NCT03637699 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT03637699 about?

NCT03637699 is a clinical study titled "A Positive Psychology Intervention for Patients With Multiple Sclerosis". Positive psychology (PP) uses targeted activities to increase the frequency and intensity of positive emotional experiences such as positive affect. Examples of PP activities include recalling positive life events and performing acts of kindness. This pilot study will examine the tolerability and ef...

What is the current status of trial NCT03637699?

This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2018-03-12. Estimated completion is 2019-04-09.

What interventions are being tested in trial NCT03637699?

The interventions under investigation include: Positive Psychology (BEHAVIORAL).

Who is sponsoring clinical trial NCT03637699?

This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT03637699's enrollment target sits among peer trials

30 1593rd of 2000 higher than 299 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00977977 · 30 participants · Phase 2

    Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

  • NCT01459107 · 30 participants · Phase 2

    Human Upper Extremity Allotransplantation

  • NCT01666080 · 30 participants · NA

    Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)

  • NCT01720836 · 30 participants · Phase 1

    Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT03637699, the US trial registry maintained by the National Library of Medicine. NCT03637699 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.