Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02805309 · ClinicalTrials.gov registry record · NA
Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement
A NA study of Aortic Valve Stenosis, sponsored by Brigham and Women's Hospital.
- Completed
- Registry status
- NA
- Development phase
- 64
- Enrollment target
- 3
- Study locations
NCT02805309: Completed NA study of Aortic Valve Stenosis, sponsored by Brigham and Women's Hospital.
NCT02805309 is a NA study of Aortic Valve Stenosis that has completed, run by Brigham and Women's Hospital. The registered enrollment target is 64 participants, below the 1,041-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (94% lower). The trial reports 3 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02805309, a NA study of Aortic Valve Stenosis, has completed, sponsored by Brigham and Women's Hospital.
- COMPLETED
- Registry status
- NA
- Development phase
- 64 participants
- Enrollment target
- 3
- Study locations
Study Summary
Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older adults with severe symptomatic aortic stenosis who are considered high risk for surgical aortic valve replacement. Despite symptomatic and survival benefits, many patients experience functional decline after TAVR. This pilot study aims to test the feasibility of a home-based exercise intervention targeting endurance, strength, and balance as well as cognitive behavioral intervention to improve physical functioning and disability after TAVR.
Primary Outcome
The LLFDI is a validated patient-reported outcome questionnaire that measures both functional limitations (inability to perform physical tasks - Activity Limitation Domain score, range: 0-100) and disability (inability to perform major life tasks and social roles - Participation Restriction Domain score, range: 0-100). For both scales, higher values indicate better function (lower limitation or lower disability). Two domain scores are analyzed separately.
Conditions Studied
Interventions
- BEHAVIORAL Exercise
- BEHAVIORAL Cognitive behavioral interventions
- BEHAVIORAL Attention control education program
Study Locations (3)
Massachusetts
- Brigham and Women's Hospital - Boston
- Hebrew SeniorLife - Boston
- Beth Israel Deaconess Medical Center - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 64 participants |
| Start Date | 2017-08-01 |
| Est. Completion | 2020-05-06 |
| Phase | NA |
What the finished NCT02805309 record still lists
NCT02805309 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 64 participants, a relatively small participant target, below the 1,041-participant average among 30 other Aortic Valve Stenosis trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Aortic Valve Stenosis appearing as the primary indexed condition, and to 3 interventions - of which Exercise is the first listed.
NCT02805309 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT02805309 about?
NCT02805309 is a clinical study titled "Home-Based Exercise Program For Recovery After Transcatheter Aortic Valve Replacement". Transcatheter aortic valve replacement (TAVR) is a minimally invasive procedure for older adults with severe symptomatic aortic stenosis who are considered high risk for surgical aortic valve replacement. Despite symptomatic and survival benefits, many patients experience functional decline after TA...
What is the current status of trial NCT02805309?
This trial is currently completed. It is a NA study. The enrollment target is 64 participants. The study started on 2017-08-01. Estimated completion is 2020-05-06.
What conditions does trial NCT02805309 study?
This clinical trial studies the following conditions: Aortic Valve Stenosis.
What interventions are being tested in trial NCT02805309?
The interventions under investigation include: Exercise (BEHAVIORAL), Cognitive behavioral interventions (BEHAVIORAL), Attention control education program (BEHAVIORAL).
Who is sponsoring clinical trial NCT02805309?
This trial is sponsored by Brigham and Women's Hospital, which has 937 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02805309 being conducted?
This trial has 3 study locations across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Aortic Valve Stenosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02805309's enrollment target sits among peer trials
64 23rd of 30 higher than 8 of 30 other Aortic Valve Stenosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Aortic Valve Stenosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Imaging Histone Deacetylase in the Heart
RECRUITING · NA
-
MRI in Transcatheter Aortic Valve Replacement Patients
RECRUITING · NA
-
ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves
RECRUITING · NA
-
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
RECRUITING · NA
-
Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial
RECRUITING · NA
-
CardioHeartConnect: Commercially Available Fitness for Cardiac Rehabilitation
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01853631 · 64 participants · Phase 1
Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)
- NCT03739502 · 64 participants · Phase 2
A Randomized Phase II Study of Hyperbaric Oxygen in Improving Engraftment in Umbilical Cord Blood Stem Cell Transplant
- NCT03739814 · 64 participants · Phase 2
Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia
- NCT03866408 · 64 participants · Early Phase 1
Insulin Regulation of Lipolysis and Lipolysis Proteins
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI