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ClinicalTrials.gov 5 recruiting now early-phase tilt #115 of 28,707 conditions

Unspecified Adult Solid Tumor, Protocol Specific: early-phase trial registry

5 of 112 indexed Unspecified Adult Solid Tumor, Protocol Specific trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #115 of 28,707 conditions by registered trial count.

112 US clinical trials · 5 currently recruiting · #115 of 28,707 conditions by registered trial count

Unspecified Adult Solid Tumor, Protocol Specific: 112 US clinical trials tracked, 5 recruiting.

Unspecified Adult Solid Tumor, Protocol Specific is the subject of 112 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 93 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 26 of these trials.

Enrollment posture brief

Registry condition unspecified-adult-solid-tumor-protocol-specific

OPEN 5 | RECR 4% | LATE 10 | EARLY 93 | RANK #115 | SPON 26

Nearest open-share peer: Attention Deficit Disorder With Hyperactivity (5% recruiting · 21 trials)

Healthy Volunteer43.4%Pain, Postoperative40.4%Fatigue30%Type 1 Diabetes Mellitus22.1%Unspecified Adult Solid (th…4%
Open-enrollment share among volume-matched conditions near Unspecified Adult Solid Tumor, Protocol Specific

Unspecified Adult Solid Tumor, Protocol Specific lists 5 open slots (4% of 112 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Unspecified Adult Solid Tumor, Protocol Specific on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Unspecified Adult Solid Tumor, Protocol Specific is recruiting below its size-band peers.

    5 of 112 indexed trials (4.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Unspecified Adult Solid Tumor, Protocol Specific research.

    National Cancer Institute (NCI) accounts for 26 of 112 trials (23.2%). 46 distinct sponsors appear on at least one study for this condition label.

  3. Most Unspecified Adult Solid Tumor, Protocol Specific trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 84 trials that report a genuine target (sentinel values excluded). 66 of those (78.6%) plan for fewer than 100 participants.

  4. Unspecified Adult Solid Tumor, Protocol Specific research is mostly interventional.

    107 interventional and 5 observational studies make up this index (95.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 185Phase 28Phase 310

Open and recent trials

112 total, page 2 of 3

COMPLETED Phase 1 38 participants

Everolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Unresectable Solid Tumors Refractory to Standard Therapy

Mayo Clinic

NCT00949949

COMPLETED Phase 2 35 participants

Stereotactic Body Radiation Therapy and Vertebroplasty in Treating Patients With Localized Spinal Metastasis

University of Texas Southwestern Medical Center

NCT00855803

COMPLETED Phase 1 33 participants

Lenalidomide and Docetaxel in Treating Patients With Advanced Solid Tumors

Case Comprehensive Cancer Center

NCT00253344

COMPLETED Phase 1 30 participants

Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00368914

COMPLETED Phase 1 30 participants

Cisplatin and Everolimus in Treating Patients With Advanced Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00423865

COMPLETED Phase 1 30 participants

Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors

University of California, Davis

NCT00389584

COMPLETED Phase 1 29 participants

Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors

University of Nebraska

NCT01206465

COMPLETED Phase 1 29 participants

Safety, Pharmacokinetics and Pharmacodynamics of BEZ235 Plus MEK162 in Selected Advanced Solid Tumor Patients

Pfizer

NCT01337765

COMPLETED Phase 1 28 participants

O(6)-Benzylguanine and Carmustine in Treating Patients With Solid Tumors

Case Comprehensive Cancer Center

NCT00002604

COMPLETED Phase 1 28 participants

BMS-214662 Plus Trastuzumab in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00022529

COMPLETED Phase 2 27 participants

Bevacizumab in Pats w/ Recurrent ST Brain Metas Who Have Failed Whole Brain Radiation Therapy

Northwestern University

NCT01898130

COMPLETED Phase 1 27 participants

1-Methyl-D-Tryptophan and Docetaxel in Treating Patients With Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT01191216

COMPLETED Phase 1 27 participants

Intraperitoneal Paclitaxel Albumin-Stabilized Nanoparticle Formulation in Treating Patients With Advanced Cancer of the Peritoneal Cavity

City of Hope Medical Center

NCT00825201

COMPLETED Phase 1 26 participants

Alisertib and Gemcitabine Hydrochloride in Treating Patients With Solid Tumors or Pancreatic Cancer

Edward Kim

NCT01924260

COMPLETED Phase 1 26 participants

Dovitinib Lactate, Gemcitabine Hydrochloride, and Capecitabine in Treating Patients With Advanced or Metastatic Solid Tumors, Pancreatic Cancer and Biliary Cancers

Roswell Park Cancer Institute

NCT01497392

COMPLETED Phase 1 25 participants

Combination Chemotherapy With or Without Filgrastim in Treating Patients With Advanced Solid Tumors

University of Pittsburgh

NCT00008125

COMPLETED Phase 1 25 participants

Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Responded to Treatment

City of Hope Medical Center

NCT00544284

COMPLETED Phase 1 25 participants

Perillyl Alcohol in Treating Patients With Refractory Cancer

National Cancer Institute (NCI)

NCT00002862

COMPLETED Phase 1 25 participants

Topotecan Plus Sargramostim in Treating Patients With Advanced Cancer

Yale University

NCT00002950

COMPLETED Phase 1 24 participants

Decitabine in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00030615

COMPLETED Phase 1 24 participants

Chemotherapy Given With Amifostine and Filgrastim in Treating Patients With Recurrent or Metastatic Cancer

Roswell Park Cancer Institute

NCT00003294

COMPLETED Phase 1 24 participants

Flavopiridol, Gemcitabine, and Irinotecan in Treating Patients With Unresectable or Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT00079352

COMPLETED Phase 2 24 participants

Vaccine Therapy, Interleukin-2, and Sargramostim in Treating Patients With Advanced Tumors

Georgetown University

NCT00003125

COMPLETED Phase 1 24 participants

3-Dimensional Conformal Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Recurrent Tumors

Fox Chase Cancer Center

NCT01470365

COMPLETED Phase 1 24 participants

Temsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT00112476

COMPLETED Phase 1 23 participants

ABT-888 in Patients With Refractory Solid Tumors or Hematologic Cancer

National Institutes of Health Clinical Center (CC)

NCT00387608

COMPLETED Phase 1 22 participants

Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

Case Comprehensive Cancer Center

NCT00006465

COMPLETED Phase 1 21 participants

Fenretinide in Treating Patients With Metastatic or Unresectable Malignant Solid Tumors

California Cancer Consortium

NCT00387504

COMPLETED Phase 1 21 participants

Irinotecan and Paclitaxel in Treating Patients With Metastatic or Recurrent Cancer

University of Chicago

NCT00002939

COMPLETED Phase 1 19 participants

An Open-Label Study to Assess the Pharmacokinetics and Safety of HALAVEN in Subjects With Cancer Who Also Have Impaired Renal Function

Eisai

NCT01418677

COMPLETED Phase 1 15 participants

Calcitriol, Ketoconazole, and Dexamethasone in Treating Patients With Metastatic or Unresectable Solid Tumors

Roswell Park Cancer Institute

NCT00238225

COMPLETED Phase 1 13 participants

Nanosomal Docetaxel Lipid Suspension in Treating Patients With Advanced Solid Tumors

University of Southern California

NCT01957995

COMPLETED Phase 1 12 participants

SU6668 in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00024206

COMPLETED Phase 1 9 participants

BMS-599626 in Treating Patients With Metastatic Solid Tumors

Jonsson Comprehensive Cancer Center

NCT00093730

COMPLETED Phase 1 3 participants

Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma

National Cancer Institute (NCI)

NCT00002759

COMPLETED Phase 1

PS-341 in Treating Patients With Advanced Solid Tumors or Lymphoma

NYU Langone Health

NCT00004002

COMPLETED Phase 1

Indole-3-Carbinol in Preventing Cancer in Healthy Participants

University of Kansas

NCT00100958

COMPLETED NA

Patient Education in Preventing Nausea and Vomiting in Cancer Patients Receiving Chemotherapy

University of Rochester

NCT00005994

COMPLETED Phase 2

Vaccine Therapy in Treating Patients With Metastatic Cancer

National Cancer Institute (NCI)

NCT00021164

COMPLETED Phase 1

BMS-247550 and Gemcitabine in Treating Patients With Advanced Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00043095

COMPLETED Phase 1

3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer

Vion Pharmaceuticals

NCT00016874

COMPLETED Phase 1

BMS-247550 in Treating Patients With Cancers That Have Not Responded to Previous Therapy

National Cancer Institute (NCI)

NCT00020371

COMPLETED Phase 1

Perifosine in Treating Patients With Refractory Solid Tumors or Hematologic Cancer

National Cancer Institute (NCI)

NCT00019656

COMPLETED Phase 1

UCN-01 in Treating Patients With Advanced Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00003289

COMPLETED Phase 1

SU5416, Irinotecan, and Cisplatin in Treating Patients With Advanced Solid Tumors

Ohio State University Comprehensive Cancer Center

NCT00006000

COMPLETED Phase 1

Perifosine in Treating Patients With Advanced Solid Tumors

University of Wisconsin, Madison

NCT00005794

COMPLETED Phase 1

Temozolomide Plus PEG-Interferon Alfa-2B in Treating Patients With Advanced Solid Tumors

Dartmouth-Hitchcock Medical Center

NCT00014261

COMPLETED Phase 1

Vaccine Therapy in Treating Patients With Advanced Cancer

Jonsson Comprehensive Cancer Center

NCT00004881

COMPLETED Phase 1

PS-341 in Treating Patients With Advanced Cancer

Mayo Clinic

NCT00006362

COMPLETED Phase 1

Fluorouracil Plus UCN-01 in Treating Patients With Advanced or Refractory Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00004059

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Phase Distribution

PhaseTrial count
Phase 1 85
Phase 2 8
Phase 3 10

Named interventions

Most-linked intervention names on Unspecified Adult Solid Tumor, Protocol Specific records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

laboratory biomarker analysis Other
18 trials
pharmacological study Other
17 trials
irinotecan hydrochloride Drug
9 trials
paclitaxel Drug
9 trials
docetaxel Drug
9 trials
gemcitabine hydrochloride Drug
8 trials
cisplatin Drug
8 trials
placebo Other
7 trials

US sites by state

Facility locations filed on Unspecified Adult Solid Tumor, Protocol Specific trials. A trial with sites in several states counts in each.

California 28 trials
New York 22 trials
Minnesota 14 trials
Florida 14 trials
Illinois 13 trials
Pennsylvania 12 trials
Texas 10 trials
Maryland 10 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Unspecified Adult Solid Tumor, Protocol Specific page

112 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Unspecified Adult Solid Tumor, Protocol Specific trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • National Cancer Institute (NCI) sponsors the most Unspecified Adult Solid Tumor, Protocol Specific trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Unspecified Adult Solid Tumor, Protocol Specific condition card totals 112 registered trials; most-linked intervention laboratory biomarker analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.