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ClinicalTrials.gov 5 recruiting now early-phase tilt #115 of 28,707 conditions

Unspecified Adult Solid Tumor, Protocol Specific: early-phase trial registry

5 of 112 indexed Unspecified Adult Solid Tumor, Protocol Specific trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #115 of 28,707 conditions by registered trial count.

112 US clinical trials · 5 currently recruiting · #115 of 28,707 conditions by registered trial count

Unspecified Adult Solid Tumor, Protocol Specific: 112 US clinical trials tracked, 5 recruiting.

Unspecified Adult Solid Tumor, Protocol Specific is the subject of 112 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 10 are in Phase 3-4 (later-stage) and 93 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 26 of these trials.

Enrollment posture brief

Registry condition unspecified-adult-solid-tumor-protocol-specific

OPEN 5 | RECR 4% | LATE 10 | EARLY 93 | RANK #115 | SPON 26

Nearest open-share peer: Attention Deficit Disorder With Hyperactivity (5% recruiting · 21 trials)

Healthy Volunteer43.4%Pain, Postoperative40.4%Fatigue30%Type 1 Diabetes Mellitus22.1%Unspecified Adult Solid (th…4%
Open-enrollment share among volume-matched conditions near Unspecified Adult Solid Tumor, Protocol Specific

Unspecified Adult Solid Tumor, Protocol Specific lists 5 open slots (4% of 112 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Unspecified Adult Solid Tumor, Protocol Specific on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Unspecified Adult Solid Tumor, Protocol Specific is recruiting below its size-band peers.

    5 of 112 indexed trials (4.5%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Unspecified Adult Solid Tumor, Protocol Specific research.

    National Cancer Institute (NCI) accounts for 26 of 112 trials (23.2%). 46 distinct sponsors appear on at least one study for this condition label.

  3. Most Unspecified Adult Solid Tumor, Protocol Specific trials plan to enrol fewer than 100 people.

    Median target enrolment is 40 among the 84 trials that report a genuine target (sentinel values excluded). 66 of those (78.6%) plan for fewer than 100 participants.

  4. Unspecified Adult Solid Tumor, Protocol Specific research is mostly interventional.

    107 interventional and 5 observational studies make up this index (95.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 185Phase 28Phase 310

Open and recent trials

112 total, page 1 of 3

RECRUITING 20,000 participants

Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors

Wake Forest University Health Sciences

NCT00900471

RECRUITING 10,000 participants

Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

University of Texas Southwestern Medical Center

NCT00992303

RECRUITING 3,000 participants

Registry of Older Patients With Cancer

UNC Lineberger Comprehensive Cancer Center

NCT01137825

RECRUITING 100 participants

Genomic Profiling in Recommending Treatment for Patients With Metastatic Solid Tumors

Stanford University

NCT02215928

RECRUITING

3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer

Barbara Ann Karmanos Cancer Institute

NCT00935090

ACTIVE NOT RECRUITING NA 1,062 participants

Assessment Tool for Older Patients With Cancer

City of Hope Medical Center

NCT00477958

ACTIVE NOT RECRUITING Phase 1 12 participants

RNR Inhibitor COH29 in Treating Patients With Solid Tumors That Are Refractory to Standard Therapy or For Which No Standard Therapy Exists

City of Hope Medical Center

NCT02112565

COMPLETED Phase 3 1,428 participants

APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer

Heron Therapeutics

NCT00343460

COMPLETED Phase 3 600 participants

Zoledronate in Treating Patients With Solid Tumors That Have Spread to the Bone

Novartis

NCT00003884

COMPLETED Phase 3 502 participants

Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer

Mayo Clinic

NCT00661999

COMPLETED Phase 3 472 participants

Comparison of Nutritional Supplements in Preventing Weight Loss in Patients With Cancer

Radiation Therapy Oncology Group

NCT00053053

COMPLETED Phase 3 376 participants

Levocarnitine in Treating Fatigue in Cancer Patients

ECOG-ACRIN Cancer Research Group

NCT00091169

COMPLETED Phase 2 361 participants

Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer

Roswell Park Cancer Institute

NCT00003816

COMPLETED Phase 3 231 participants

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Alliance for Clinical Trials in Oncology

NCT00489411

COMPLETED Phase 3 227 participants

(Valerian) for Improving Sleep in Patients With Cancer Receiving Adjuvant Therapy

Alliance for Clinical Trials in Oncology

NCT00075842

COMPLETED Phase 2 226 participants

Cognitive Behavioral Therapy With or Without Armodafinil in Treating Cancer Survivors With Insomnia and Fatigue After Chemotherapy

Abramson Cancer Center at Penn Medicine

NCT01019187

COMPLETED Phase 3 148 participants

Methylphenidate in Treating Patients With Fatigue Caused by Cancer

Alliance for Clinical Trials in Oncology

NCT00376675

COMPLETED Phase 1 140 participants

Irinotecan in Treating Aging Patients With Solid Tumors

Alliance for Clinical Trials in Oncology

NCT00026195

COMPLETED NA 140 participants

White Wine or Nutritional Supplement in Improving Appetite in Patients With Cancer

Academic and Community Cancer Research United

NCT00936728

COMPLETED Phase 2 109 participants

Docetaxel in Treating Patients With Solid Tumors

Alliance for Clinical Trials in Oncology

NCT00003565

COMPLETED Phase 1 96 participants

PS-341 and Combination Chemotherapy in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00028587

COMPLETED 93 participants

Assessing Older Patients With Cancer

Alliance for Clinical Trials in Oncology

NCT00416481

COMPLETED Phase 1 80 participants

Combination Chemotherapy in Treating Patients With Metastatic or Unresectable Solid Tumors

National Cancer Institute (NCI)

NCT00058253

COMPLETED Phase 1 78 participants

Tanespimycin, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00047047

COMPLETED Phase 1 73 participants

Combination Chemotherapy in Treating Patients With Refractory or Recurrent Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00003004

COMPLETED Early Phase 1 65 participants

Fludeoxyglucose F 18 PET/CT Imaging in Finding Cancer in Patients Undergoing Surgery for Solid Tumors

Ohio State University Comprehensive Cancer Center

NCT00816335

COMPLETED Phase 1 64 participants

Erlotinib and Cetuximab in Treating Patients With Advanced Solid Tumors With Emphasis on Non-Small Cell Lung Cancer

University of California, Davis

NCT00408499

COMPLETED Phase 1 60 participants

2-Methoxyestradiol in Treating Patients With Advanced Solid Tumors

National Cancer Institute (NCI)

NCT00028821

COMPLETED Phase 1 59 participants

Docetaxel, Oxaliplatin, and Fluorouracil in Treating Patients With Metastatic or Unresectable Stomach Cancer, Gastroesophageal Junction Cancer, or Other Solid Tumor

Northwestern University

NCT00711243

COMPLETED Phase 1 54 participants

Suberoylanilide Hydroxamic Acid, Fluorouracil, Leucovorin, and Oxaliplatin in Treating Patients With Progressive Metastatic or Unresectable Colorectal Cancer or Other Solid Tumors

National Cancer Institute (NCI)

NCT00138177

COMPLETED Phase 1 54 participants

Bortezomib and Topotecan Hydrochloride in Treating Patients With Advanced Solid Tumors

City of Hope Medical Center

NCT00541359

COMPLETED Phase 1 52 participants

1-Methyl-D-Tryptophan in Treating Patients With Metastatic or Refractory Solid Tumors That Cannot Be Removed By Surgery

National Cancer Institute (NCI)

NCT00567931

COMPLETED Phase 1 50 participants

EF5 in Treating Patients With Solid Tumors

National Cancer Institute (NCI)

NCT00003282

COMPLETED Phase 1 50 participants

LY231514 in Treating Patients With Locally Advanced or Metastatic Solid Tumors and Varying Degrees of Kidney Function

The University of Texas Health Science Center at San Antonio

NCT00003706

COMPLETED Phase 1 50 participants

Sorafenib and Bortezomib in Treating Patients With Advanced Cancer

National Cancer Institute (NCI)

NCT00303797

COMPLETED Phase 1 47 participants

Docetaxel and Irinotecan in Treating Patients With Advanced Solid Tumors

Yale University

NCT00004923

COMPLETED Phase 1 45 participants

Bortezomib and Paclitaxel in Treating Patients With Locally Advanced or Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT00030368

COMPLETED Phase 1 45 participants

Calcitriol Plus Paclitaxel in Treating Patients With Advanced Solid Tumors

University of Pittsburgh

NCT00009802

COMPLETED Phase 2 44 participants

S0916, MLN1202 in Treating Patients With Bone Metastases

SWOG Cancer Research Network

NCT01015560

COMPLETED Phase 1 44 participants

Combination Therapy With Oral 9-Nitrocamptothecin & Oral Etoposide

H. Lee Moffitt Cancer Center and Research Institute

NCT00006047

COMPLETED Phase 1 44 participants

PI-88 in Treating Patients With an Advanced Malignancy (Cancer) or Stage IV Melanoma

Cellxpert Biotechnology

NCT00073892

COMPLETED Phase 1 44 participants

Tirapazamine, Carboplatin, and Paclitaxel in Treating Patients With Advanced Malignant Solid Tumors

City of Hope Medical Center

NCT00005078

COMPLETED Phase 1 43 participants

Safingol and Cisplatin in Treating Patients With Locally Advanced or Metastatic Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00084812

COMPLETED Phase 1 40 participants

L-778,123 in Treating Patients With Recurrent or Refractory Solid Tumors

Memorial Sloan Kettering Cancer Center

NCT00003430

COMPLETED Phase 1 40 participants

Imatinib Mesylate and Bevacizumab in Treating Patients With Advanced Melanoma or Other Advanced Cancers

National Cancer Institute (NCI)

NCT00074308

COMPLETED Phase 1 40 participants

Sorafenib and Temsirolimus in Treating Patients With Unresectable or Metastatic Solid Tumors

National Cancer Institute (NCI)

NCT00255658

COMPLETED Phase 1 40 participants

UMCC 2003-064 Resveratrol in Preventing Cancer in Healthy Participants

National Cancer Institute (NCI)

NCT00098969

COMPLETED Phase 1 40 participants

GTI-2040 and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors

National Cancer Institute (NCI)

NCT00078962

COMPLETED Phase 1 40 participants

Ro 31-7453 in Treating Patients With Locally Advanced or Metastatic Solid Tumor

Memorial Sloan Kettering Cancer Center

NCT00003755

COMPLETED Phase 1 38 participants

Hydroxychloroquine and Temozolomide in Treating Patients With Metastatic or Unresectable Solid Tumors

Abramson Cancer Center at Penn Medicine

NCT00714181

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Phase Distribution

PhaseTrial count
Phase 1 85
Phase 2 8
Phase 3 10

Named interventions

Most-linked intervention names on Unspecified Adult Solid Tumor, Protocol Specific records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

laboratory biomarker analysis Other
18 trials
pharmacological study Other
17 trials
irinotecan hydrochloride Drug
9 trials
paclitaxel Drug
9 trials
docetaxel Drug
9 trials
gemcitabine hydrochloride Drug
8 trials
cisplatin Drug
8 trials
placebo Other
7 trials

US sites by state

Facility locations filed on Unspecified Adult Solid Tumor, Protocol Specific trials. A trial with sites in several states counts in each.

California 28 trials
New York 22 trials
Minnesota 14 trials
Florida 14 trials
Illinois 13 trials
Pennsylvania 12 trials
Texas 10 trials
Maryland 10 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Unspecified Adult Solid Tumor, Protocol Specific page

112 registered trials, 5 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 5 Unspecified Adult Solid Tumor, Protocol Specific trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • National Cancer Institute (NCI) sponsors the most Unspecified Adult Solid Tumor, Protocol Specific trials on record, review their full trial history before evaluating a specific study. See National Cancer Institute (NCI)'s trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Unspecified Adult Solid Tumor, Protocol Specific condition card totals 112 registered trials; most-linked intervention laboratory biomarker analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.