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NCT00368914 · ClinicalTrials.gov registry record · Phase 1

Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors

A Phase 1 study of Unspecified Adult Solid Tumor, Protocol Specific, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

Completed
Registry status
Phase 1
Development phase
30
Enrollment target
1
Study location

NCT00368914 is a Phase 1 study of Unspecified Adult Solid Tumor, Protocol Specific that has completed, run by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. The registered enrollment target is 30 participants, below the 501-participant average among 83 other Unspecified Adult Solid Tumor, Protocol Specific trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00368914, a Phase 1 study of Unspecified Adult Solid Tumor, Protocol Specific, has completed, sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins.

COMPLETED
Registry status
Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

RATIONALE: Sirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of sirolimus in treating patients with metastatic or unresectable solid tumors.

Interventions

  • OTHER laboratory biomarker analysis
  • PROCEDURE biopsy
  • OTHER pharmacological study
  • DRUG sirolimus

Study Locations (1)

Maryland

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins - Baltimore

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2004-12
Est. Completion 2009-06
Phase Phase 1

What the Registry Record Tells You About NCT00368914

The ClinicalTrials.gov registry entry for NCT00368914 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 501-participant average among 83 other Unspecified Adult Solid Tumor, Protocol Specific trials with a reported enrollment target (94% lower). The listed sponsor is Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Unspecified Adult Solid Tumor, Protocol Specific appearing as the primary indexed condition, and to 4 interventions - of which laboratory biomarker analysis is the first listed.

NCT00368914 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00368914 about?

NCT00368914 is a clinical study titled "Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors". RATIONALE: Sirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase I trial is studying the side effects and best dose of sirolimus in treating patients with metastatic or unresectable solid tumors.

What is the current status of trial NCT00368914?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2004-12. Estimated completion is 2009-06.

What conditions does trial NCT00368914 study?

This clinical trial studies the following conditions: Unspecified Adult Solid Tumor, Protocol Specific.

What interventions are being tested in trial NCT00368914?

The interventions under investigation include: laboratory biomarker analysis (OTHER), biopsy (PROCEDURE), pharmacological study (OTHER), sirolimus (DRUG).

Who is sponsoring clinical trial NCT00368914?

This trial is sponsored by Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, which has 523 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00368914 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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