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NCT00002759 · ClinicalTrials.gov registry record · Phase 1

Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma

A Phase 1 study of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific, sponsored by National Cancer Institute (NCI).

Completed
Registry status
Phase 1
Development phase
3
Enrollment target
1
Study location

NCT00002759 is a Phase 1 study of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 3 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00002759, a Phase 1 study of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific, has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
Phase 1
Development phase
3 participants
Enrollment target
1
Study location

Study Summary

Phase I trial to study the effectiveness of irinotecan plus cyclosporine and phenobarbital in treating patients who have solid tumors or lymphoma that is refractory to standard therapy. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Cyclosporine and phenobarbital may enhance the effectiveness of irinotecan.

Interventions

  • DRUG irinotecan hydrochloride
  • DRUG cyclosporine
  • DRUG phenobarbital

Study Locations (1)

Illinois

  • University of Chicago Cancer Research Center - Chicago

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 1996-06
Phase Phase 1

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00002759

The ClinicalTrials.gov registry entry for NCT00002759 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which irinotecan hydrochloride is the first listed.

NCT00002759 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT00002759 about?

NCT00002759 is a clinical study titled "Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma". Phase I trial to study the effectiveness of irinotecan plus cyclosporine and phenobarbital in treating patients who have solid tumors or lymphoma that is refractory to standard therapy. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Cycl...

What is the current status of trial NCT00002759?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 3 participants. The study started on 1996-06.

What conditions does trial NCT00002759 study?

This clinical trial studies the following conditions: Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific, Neutropenia, Small Intestine Cancer, Drug/Agent Toxicity by Tissue/Organ.

What interventions are being tested in trial NCT00002759?

The interventions under investigation include: irinotecan hydrochloride (DRUG), cyclosporine (DRUG), phenobarbital (DRUG).

Who is sponsoring clinical trial NCT00002759?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00002759 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.