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Type 2 Diabetes: full-pipeline trial registry
120 of 328 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #22 of 28,707 conditions by registered trial count.
328 US clinical trials · 120 currently recruiting · #22 of 28,707 conditions by registered trial count
Type 2 Diabetes: 328 US clinical trials tracked, 120 recruiting.
Type 2 Diabetes is the subject of 328 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 60 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes
OPEN 120 | RECR 37% | LATE 60 | EARLY 50 | RANK #22 | SPON 20
Volume-matched condition peers
Nearest open-share peer: Advanced Cancer (37% recruiting · 123 trials)
Type 2 Diabetes lists 120 open slots (37% of 328 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
120 of 328 indexed trials (36.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 328 trials (6.1%). 153 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 328 trials that report a genuine target (sentinel values excluded). 166 of those (50.6%) plan for fewer than 100 participants.
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Type 2 Diabetes research is mostly interventional.
290 interventional and 38 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
328 total, page 6 of 7
Pilot RCT Evaluating Clinical Outcomes of Using Undermyfork Mobile App With Dexcom G7
Scripps Whittier Diabetes Institute
NCT06501612
Social Support Intervention for Older Adults With T2DM
Brittany L Smalls
NCT04568486
Medical Nutrition Therapy and Diabetes Self-Management Education for People With Disabilities
University of Alabama at Birmingham
NCT06049225
Diabetes Group Prenatal Care
Washington University School of Medicine
NCT02444325
A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes
Response Pharmaceuticals
NCT00871936
Nutrition Outreach and Understanding: Research In Serving Hearts Through Healthy Eating And Tailored Support
Amanda Shallcross
NCT06460272
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
Cleveland Clinic Akron General
NCT05174078
Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes
Johns Hopkins Bloomberg School of Public Health
NCT00831194
Pistachios Blood Sugar Control, Heart and Gut Health
Penn State University
NCT04056208
Treatment Burden Screening Questionnaire Pilot Study
University of Minnesota
NCT05870202
Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes
Eli Lilly and Company
NCT00191178
Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT01223196
Improving Diabetes Outcomes Through Lifestyle Change (IDOLc)Study
Massachusetts General Hospital
NCT01665989
Blueberry Consumption and Type 2 Diabetes
Albany Research Institute
NCT02972996
The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00339833
Eliminating Hepatitis C Virus
Icahn School of Medicine at Mount Sinai
NCT03401697
The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
Loma Linda University
NCT01211717
The Impact of Food on Blood Sugar in People With Type 2 Diabetes
HealthPartners Institute
NCT01237314
Dapagliflozin and Measures of Cardiovascular Autonomic Function in Patients With Type 2 Diabetes (T2D)
University of Michigan
NCT02973477
Antioxidant Treatment of Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00609102
Exercise and Pioglitazone for HIV-Metabolic Syndromes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00639457
Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes
In-Young Choi, Ph.D.
NCT00845130
Effect of Saxagliptin on EPCs as a Cellular Biomarker for Evaluating Endothelial Dysfunction in Early T2DM Patients
George Washington University
NCT02024477
Effect of Glycemic Variability on Autonomic Tone in Hospitalized Patients With Type 2 Diabetes
Kathleen Dungan
NCT01409239
Taking Action: a Care for Type 2 Diabetes Intervention for Couples
Carnegie Mellon University
NCT04014582
The VALIDATE-D Study
Brigham and Women's Hospital
NCT01635062
Exercise and Type 2 Diabetes: Gender and Endothelial Function
University of Colorado, Denver
NCT01993121
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Christos Mantzoros
NCT00525629
Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans
University of California, San Diego
NCT01375491
Methylglyoxal Evaluation in Humans
University of Kansas Medical Center
NCT05350553
Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-686117 in Subjects With Type 2 Diabetes
Bristol-Myers Squibb
NCT00508287
The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
Texas Tech University
NCT06016478
Barriers to Physical Activity in People With Type 2 Diabetes
University of Colorado, Denver
NCT01701570
TREAT (Telemedicine for Reach, Education, Access, and Treatment)
University of Pittsburgh
NCT01339208
Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT04791787
The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT04316429
Family Diabetes Prevention Program Pilot Study
Johns Hopkins University
NCT05358444
TARDIS - Photo Elicitation and Intervention
VA Office of Research and Development
NCT06972251
Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 1
Vanderbilt University
NCT00574665
African American Children, Glycemic Control, and Type 2 Diabetes
University of Alabama at Birmingham
NCT01325987
Technology Based Sedentary Reduction Intervention in Patients With Type 2 Diabetes
Vanderbilt University
NCT05691452
The Effect and Safety of a Novel CGM-Based Titration Algorithm for Basal Insulin in T2DM Participants.
University of Virginia
NCT06111508
A Mindfulness-based Intervention for Adolescents With Prediabetes or Type 2 Diabetes
Indiana University
NCT07270900
Blood Flow Responses to an Oral Glucose Tolerance Test in Type 2 Diabetes
University of Kansas Medical Center
NCT00972452
NUTRITION MATTERS: A Food is Medicine Intervention for African-American Adults With Multiple Chronic Conditions
Winston Salem State University
NCT06933940
Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes
AstraZeneca
NCT01204775
Walnut Consumption, Endothelial Function, and Biomarkers
Brigham and Women's Hospital
NCT01884363
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Healthy Subjects
Foundation for the National Institutes of Health
NCT01454973
Diabetes Pueblo Program - Application and Acceptability of Culturally Appropriate Latino Education for Insulin Therapy
Sansum Diabetes Research Institute
NCT04016584
The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance
Massachusetts General Hospital
NCT02509065
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 25 |
| Phase 2 | 25 |
| Phase 3 | 35 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes page
328 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Type 2 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Type 2 Diabetes trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes condition card totals 328 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.