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Type 2 Diabetes: full-pipeline trial registry
103 of 289 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #30 of 28,963 conditions by registered trial count.
289 US clinical trials · 103 currently recruiting · #30 of 28,963 conditions by registered trial count
Type 2 Diabetes: 289 US clinical trials tracked, 103 recruiting.
Type 2 Diabetes is the subject of 289 registered US clinical trials on ClinicalTrials.gov, 103 of them currently open to new participants. 56 are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Open enrollment snapshot
Type 2 Diabetes has 289 registered US clinical trials, 103 of them open to new participants right now, about 36% of the total.
- 103
- recruiting participants now
- 36%
- of trials open to enrollment
- 56
- in Phase 3-4 (later-stage)
- 20
- top sponsor: Eli Lilly and Company
Corpus placement: #30 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
103 of 289 indexed trials (35.6%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 289 trials (6.9%). 140 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 289 trials that report a genuine target (sentinel values excluded). 145 of those (50.2%) plan for fewer than 100 participants.
-
Type 2 Diabetes research is mostly interventional.
257 interventional and 32 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
289 total, page 6 of 6
TREAT (Telemedicine for Reach, Education, Access, and Treatment)
University of Pittsburgh
NCT01339208
Effect of Ketogenic Diet on Glucose Metabolism and Energy Expenditure in Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT04791787
The Impact of Consumption of Eggs in the Context of Plant-Based Diets on Endothelial Function, Diet Quality, and Cardio-Metabolic Risk Factors in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT04316429
Family Diabetes Prevention Program Pilot Study
Johns Hopkins University
NCT05358444
TARDIS - Photo Elicitation and Intervention
VA Office of Research and Development
NCT06972251
Metabolic Causes of Thrombosis in Type 2 Diabetes - Question 1
Vanderbilt University
NCT00574665
African American Children, Glycemic Control, and Type 2 Diabetes
University of Alabama at Birmingham
NCT01325987
Technology Based Sedentary Reduction Intervention in Patients With Type 2 Diabetes
Vanderbilt University
NCT05691452
The Effect and Safety of a Novel CGM-Based Titration Algorithm for Basal Insulin in T2DM Participants.
University of Virginia
NCT06111508
A Mindfulness-based Intervention for Adolescents With Prediabetes or Type 2 Diabetes
Indiana University
NCT07270900
Blood Flow Responses to an Oral Glucose Tolerance Test in Type 2 Diabetes
University of Kansas Medical Center
NCT00972452
NUTRITION MATTERS: A Food is Medicine Intervention for African-American Adults With Multiple Chronic Conditions
Winston Salem State University
NCT06933940
Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes
AstraZeneca
NCT01204775
Walnut Consumption, Endothelial Function, and Biomarkers
Brigham and Women's Hospital
NCT01884363
Characterization of the Variability of Insulin Secretory Parameters in the Meal Tolerance and the Maximal Stimulation Tests of Healthy Subjects
Foundation for the National Institutes of Health
NCT01454973
The Set-Point Study: Evaluating Effects of Changing Glucose Target on Bionic Pancreas Performance
Massachusetts General Hospital
NCT02509065
Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT01142297
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02960659
INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes
Ohio University
NCT01087567
Impact of Exenatide on Cardiovascular Exercise Performance in Type 2 Diabetes
University of Colorado, Denver
NCT01364584
Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes
University of Chicago
NCT01136785
Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function
University of California, San Diego
NCT01671514
Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.
University of Chicago
NCT00720889
The Effect of Exercise on Hepatic Glucose Metabolism
Vanderbilt University
NCT01783275
Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT04025281
A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care
University of Texas Southwestern Medical Center
NCT00939250
Impact of Exenatide on Sleep in Type 2 Diabetes
University of Chicago
NCT01136798
Continuous Glucose Monitoring in Youth With Type 2 Diabetes
Yale University
NCT02293577
24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine
Eli Lilly and Company
NCT00551538
Using Continuous Glucose Monitoring to Understand the Glycemic Impact of Food
HealthPartners Institute
NCT00818077
Nutrition-Focused Approach During CGM Initiation: A Qualitative Study
HealthPartners Institute
NCT05988957
Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes
University of Massachusetts, Worcester
NCT02132442
To Evaluate the Hormonal Response to Low Blood Sugar After a Single Oral Dose of AZD1656 Suspension
AstraZeneca
NCT00790153
Exercise and Diabetes - an Observational Study of Exercise and Blood Glucose Control
Sansum Diabetes Research Institute
NCT02190669
Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
Tulane University School of Medicine
NCT02796170
Diabetes Homeless Medication Support Single Arm Treatment Development Trial
Hennepin Healthcare Research Institute
NCT04678284
Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
Minneapolis Veterans Affairs Medical Center
NCT01469104
Intervention Mapping to Adapt a Mindfulness-based Intervention for Adults With Diabetes and Emotional Distress
University of Alabama at Birmingham
NCT03987841
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
The University of Texas Health Science Center at San Antonio
NCT05093517
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 21 |
| Phase 3 | 34 |
| Phase 4 | 22 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Type 2 Diabetes right now
103 recruiting of 289 indexed (36% open).
Phase mix: 56 late (III/IV) vs 42 early (I/II) (balanced across stages).
Top sponsor: Eli Lilly and Company (20 trials), 9 others listed. 39 shown below, recruiting first. #30 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Type 2 Diabetes?
PlainTrial tracks 289 US clinical trials for Type 2 Diabetes, of which 103 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Type 2 Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.