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Type 2 Diabetes: full-pipeline trial registry
120 of 328 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #22 of 28,707 conditions by registered trial count.
328 US clinical trials · 120 currently recruiting · #22 of 28,707 conditions by registered trial count
Type 2 Diabetes: 328 US clinical trials tracked, 120 recruiting.
Type 2 Diabetes is the subject of 328 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 60 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes
OPEN 120 | RECR 37% | LATE 60 | EARLY 50 | RANK #22 | SPON 20
Volume-matched condition peers
Nearest open-share peer: Advanced Cancer (37% recruiting · 123 trials)
Type 2 Diabetes lists 120 open slots (37% of 328 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
120 of 328 indexed trials (36.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 328 trials (6.1%). 153 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 328 trials that report a genuine target (sentinel values excluded). 166 of those (50.6%) plan for fewer than 100 participants.
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Type 2 Diabetes research is mostly interventional.
290 interventional and 38 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
328 total, page 7 of 7
Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT01142297
Title: Therapeutic Targets in African-American Youth With Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02960659
The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans
Purdue University
NCT05349916
INSPIRE Diabetes Study: Basal Bolus Insulin as Primary Treatment of Type 2 Diabetes
Ohio University
NCT01087567
Impact of Exenatide on Cardiovascular Exercise Performance in Type 2 Diabetes
University of Colorado, Denver
NCT01364584
Effects of Continuous Positive Airway Pressure (CPAP) Treatment on Glucose Control in Patients With Type 2 Diabetes
University of Chicago
NCT01136785
Effects of Dark Chocolate on Exercise Capacity, and Mitochondrial Structure and Function
University of California, San Diego
NCT01671514
Glucose Metabolism and Sleep in People With Family History of Type 2 Diabetes.
University of Chicago
NCT00720889
The Effect of Exercise on Hepatic Glucose Metabolism
Vanderbilt University
NCT01783275
Post-prandial Effects of Extra Virgin Olive Oil on Endothelial Function in Adults at Risk for Type 2 Diabetes
Griffin Hospital
NCT04025281
A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care
University of Texas Southwestern Medical Center
NCT00939250
An Emotion-Focused Intervention for Glycemic Control in T2D
University of Chicago
NCT03553680
Initiating Mealtime Ultra-Rapid Acting Insulin (Afrezza) in Uncontrolled Type 2 Diabetes Patients
Model Clinical Research
NCT03324776
Impact of Exenatide on Sleep in Type 2 Diabetes
University of Chicago
NCT01136798
Continuous Glucose Monitoring in Youth With Type 2 Diabetes
Yale University
NCT02293577
24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine
Eli Lilly and Company
NCT00551538
Using Continuous Glucose Monitoring to Understand the Glycemic Impact of Food
HealthPartners Institute
NCT00818077
Nutrition-Focused Approach During CGM Initiation: A Qualitative Study
HealthPartners Institute
NCT05988957
Hypoglycemia and Autonomic Nervous System Function- B2
Brigham and Women's Hospital
NCT03422471
Hepatic Dysfunction, Vitamin D Status, and Glycemic Control in Diabetes
University of Massachusetts, Worcester
NCT02132442
To Evaluate the Hormonal Response to Low Blood Sugar After a Single Oral Dose of AZD1656 Suspension
AstraZeneca
NCT00790153
Exercise and Diabetes - an Observational Study of Exercise and Blood Glucose Control
Sansum Diabetes Research Institute
NCT02190669
Inhibition of Urinary Angiotensinogen and the Reduction of Blood Pressure by SGLT2 Inhibition in Patients With Type 2 Diabetes
Tulane University School of Medicine
NCT02796170
Diabetes Homeless Medication Support Single Arm Treatment Development Trial
Hennepin Healthcare Research Institute
NCT04678284
Almond Butter and Fasting Glucose
Penn State University
NCT03826472
Metabolic Response to 3-day Fast Versus Carbohydrate-free Diet in Type 2 Diabetes
Minneapolis Veterans Affairs Medical Center
NCT01469104
Intervention Mapping to Adapt a Mindfulness-based Intervention for Adults With Diabetes and Emotional Distress
University of Alabama at Birmingham
NCT03987841
Effect of Novel Glucagon Receptor Antagonist REMD-477 on Glucose and Adipocyte Metabolism in T2DM
The University of Texas Health Science Center at San Antonio
NCT05093517
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 25 |
| Phase 2 | 25 |
| Phase 3 | 35 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes page
328 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Type 2 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Type 2 Diabetes trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes condition card totals 328 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.