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Type 2 Diabetes: full-pipeline trial registry
120 of 328 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #22 of 28,707 conditions by registered trial count.
328 US clinical trials · 120 currently recruiting · #22 of 28,707 conditions by registered trial count
Type 2 Diabetes: 328 US clinical trials tracked, 120 recruiting.
Type 2 Diabetes is the subject of 328 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 60 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Enrollment posture brief
Registry condition type-2-diabetes
OPEN 120 | RECR 37% | LATE 60 | EARLY 50 | RANK #22 | SPON 20
Volume-matched condition peers
Nearest open-share peer: Advanced Cancer (37% recruiting · 123 trials)
Type 2 Diabetes lists 120 open slots (37% of 328 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
120 of 328 indexed trials (36.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 328 trials (6.1%). 153 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 328 trials that report a genuine target (sentinel values excluded). 166 of those (50.6%) plan for fewer than 100 participants.
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Type 2 Diabetes research is mostly interventional.
290 interventional and 38 observational studies make up this index (88.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
328 total, page 5 of 7
Evaluation of Evolocumab (AMG 145) Efficacy in Diabetic Adults With Hypercholesterolemia/Mixed Dyslipidemia
Amgen
NCT02739984
Safety and Efficacy Study of Metaglidasen in Type 2 Diabetes in Patients Suboptimally Controlled on Insulin
Gilead Sciences
NCT00353587
An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol
Novartis Pharmaceuticals
NCT03060577
Study to Evaluate the Safety, Tolerability and Efficacy of Three Dose Levels of Mitoglitazone in Type 2 Diabetic Patients
Metabolic Solutions Development Company
NCT01103414
Comparison of Technosphere® Insulin Versus Technosphere Powder (Placebo) in Insulin-Naive Subjects With Type 2 Diabetes Mellitus
Mannkind Corporation
NCT01451398
Impact of SomaSignal Tests on the Choice of Glucose-lowering Medications
University of Colorado, Denver
NCT05166382
Family Model Diabetes Self-Management Education in Faith Based Organizations
University of Arkansas
NCT04256486
A Study of Investigational Dulaglutide Doses in Participants With Type 2 Diabetes on Metformin Monotherapy
Eli Lilly and Company
NCT02973100
Safety and Efficacy of Saxagliptin in Triple Therapy to Treat Subjects With Type 2 Diabetes
AstraZeneca
NCT01619059
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
Albert Einstein College of Medicine
NCT04104243
WelChol® With Metformin in Treating Patients With Type 2 Diabetes
Daiichi Sankyo
NCT00147719
Changing Health Through Food Support for Diabetes
University of California, San Francisco
NCT04959487
Targeting INflammation Using SALsalate in Type 2 Diabetes (TINSAL-T2D)
Joslin Diabetes Center
NCT00392678
Diabetes Support Project: Couples Intervention
State University of New York - Upstate Medical University
NCT01017523
REMEDIES4D: REdesigning MEDication Intensification Effectiveness Study for Diabetes
University of Pittsburgh
NCT01611168
Taking Action Together- A Diabetes Prevention Program
University of California, Berkeley
NCT01039116
Study to Evaluate the Effect of BYDUREON on 24-hour Glucose Control in Metformin Treated Patients With Type 2 Diabetes.
AstraZeneca
NCT02288273
UCSD Take Charge Study
University of California, San Diego
NCT01345500
Trial to Determine the Effects of Bardoxolone Methyl on eGFR in Patients With Type 2 Diabetes and Chronic Kidney Disease
Biogen
NCT00811889
Study To Evaluate 24 Hour Blood Sugar Control (24-hour Mean Weighted Glucose) In Subjects That Are Taking Saxagliptin 5 mg Added Onto Metformin XR 1500 XR mg Compared To Subjects Taking Metformin XR 1500 mg Up-titrated To Metformin XR 2000 mg
AstraZeneca
NCT00918138
A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Safety and Efficacy of KRP-104 in Patients With Type 2 Diabetes Inadequately Controlled on Metformin Alone
ActivX Biosciences
NCT00525330
Physical Health in Midlife: Influences of Adversity and Relationships Over Time
Beth Israel Deaconess Medical Center
NCT01853332
Medically Tailored Groceries and Food Resource Coaching
University of Texas Southwestern Medical Center
NCT06242808
Glycaemic Control of Monthly LAPS-Exendin Versus Placebo in Subjects of Type 2 Diabetes
Hanmi Pharmaceutical Company Limited
NCT02081118
Video Games for Obesity and Diabetes Prevention-Diab & Nano
Baylor College of Medicine
NCT01846377
A Study of Mealtime Insulin LY900014 in Participants With Type 2 Diabetes Using Continuous Glucose Monitoring (PRONTO-Time in Range)
Eli Lilly and Company
NCT04605991
A Trial of INS068 in Patients With Type 2 Diabetes Not Adequately Controlled With One or Two Oral Antidiabetics
Jiangsu HengRui Medicine Co.
NCT04663282
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Daiichi Sankyo
NCT00484419
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
US Department of Veterans Affairs
NCT00108459
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
Emory University
NCT02455076
Pragmatic Impact of Proteomic Risk Stratification in Diabetes Mellitus
University Hospitals Cleveland Medical Center
NCT05182359
Program ACTIVE II: Behavioral Depression Treatment for Type 2 Diabetes
Indiana University
NCT03371940
Automated Insulin Delivery for Inpatients With Dysglycemia
Emory University
NCT06418880
A Safety Study of ARRY-403 in Patients With Type 2 Diabetes
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT00952198
Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes
University of Florida
NCT01883258
Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency
Loyola University
NCT00911625
Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men
Pennington Biomedical Research Center
NCT01787617
Worksite Nutrition Study
Physicians Committee for Responsible Medicine
NCT00481897
Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk in Patients With Type 2 Diabetes
Joslin Diabetes Center
NCT02895867
The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
Walter Reed National Military Medical Center
NCT01738802
Dietary Approaches to Stop Hypertension for Diabetes
Johns Hopkins University
NCT04286555
The Health Influences of Puberty (HIP) Study
University of Colorado, Denver
NCT01775813
A Study to Assess the Effect of Psyllium vs. Wheat Dextrin on Glycemic Control and Inflammatory Markets in Diabetes Mellitus 2
Mayo Clinic
NCT04547790
Randomized Trial to Evaluate the Effectiveness of Nurse Case Management
Johns Hopkins University
NCT00295256
Partners in Care Diabetes Self-management Intervention
University of Hawaii
NCT01235429
Evaluation of a Digital Diabetes Self-Management Education and Support Program
Omada Health
NCT05368454
Progression and Etiology of Cortical Porosity in Diabetic Bone Disease
University of California, San Francisco
NCT04208230
Pharmacokinetic Study of Vildagliptin in Patients With Renal Impairment
Novartis
NCT00567047
Effects of Nasulin Versus Placebo on Blood Glucose Control in Patient Volunteers With Type 2 Diabetes Mellitus
CPEX Pharmaceuticals
NCT00850096
Vitamin D Supplementation on Cardiovascular Risk Factors
Florida International University
NCT01412710
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 25 |
| Phase 2 | 25 |
| Phase 3 | 35 |
| Phase 4 | 25 |
Top Sponsors
Named interventions
Most-linked intervention names on Type 2 Diabetes records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Type 2 Diabetes trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Type 2 Diabetes page
328 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Type 2 Diabetes trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Eli Lilly and Company sponsors the most Type 2 Diabetes trials on record, review their full trial history before evaluating a specific study. See Eli Lilly and Company's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Type 2 Diabetes condition card totals 328 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.