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Type 2 Diabetes: full-pipeline trial registry
103 of 289 indexed Type 2 Diabetes trials are currently recruiting.
Corpus placement: #30 of 28,963 conditions by registered trial count.
289 US clinical trials · 103 currently recruiting · #30 of 28,963 conditions by registered trial count
Type 2 Diabetes: 289 US clinical trials tracked, 103 recruiting.
Type 2 Diabetes is the subject of 289 registered US clinical trials on ClinicalTrials.gov, 103 of them currently open to new participants. 56 are in Phase 3-4 (later-stage) and 42 in Phase 1-2 (earlier-stage). The most active sponsor is Eli Lilly and Company, running 20 of these trials.
Open enrollment snapshot
Type 2 Diabetes has 289 registered US clinical trials, 103 of them open to new participants right now, about 36% of the total.
- 103
- recruiting participants now
- 36%
- of trials open to enrollment
- 56
- in Phase 3-4 (later-stage)
- 20
- top sponsor: Eli Lilly and Company
Corpus placement: #30 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Type 2 Diabetes on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Type 2 Diabetes recruits in line with its size-band peers.
103 of 289 indexed trials (35.6%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Type 2 Diabetes trials is spread across many organizations.
Eli Lilly and Company accounts for 20 of 289 trials (6.9%). 140 distinct sponsors appear on at least one study for this condition label.
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Typical Type 2 Diabetes enrolment sits around 96 participants.
Median target enrolment is 96 among the 289 trials that report a genuine target (sentinel values excluded). 145 of those (50.2%) plan for fewer than 100 participants.
-
Type 2 Diabetes research is mostly interventional.
257 interventional and 32 observational studies make up this index (88.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
289 total, page 5 of 6
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Daiichi Sankyo
NCT00484419
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
US Department of Veterans Affairs
NCT00108459
Exenatide Inpatient Trial: A Randomized Controlled Pilot Trial on the Safety and Efficacy of Exenatide (Byetta®) Therapy for the Inpatient Management of Patients With Type 2 Diabetes
Emory University
NCT02455076
Pragmatic Impact of Proteomic Risk Stratification in Diabetes Mellitus
University Hospitals Cleveland Medical Center
NCT05182359
Automated Insulin Delivery for Inpatients With Dysglycemia
Emory University
NCT06418880
A Safety Study of ARRY-403 in Patients With Type 2 Diabetes
Array Biopharma, now a wholly owned subsidiary of Pfizer
NCT00952198
Effect of Aerobic Interval Training on Cardiovascular Function in Type 2 Diabetes
University of Florida
NCT01883258
Glargine Dosing in Hospitalized Patients With Type 2 Diabetes and Renal Insufficiency
Loyola University
NCT00911625
Aerobic Plus Resistance Training and Insulin Sensitivity in African American Men
Pennington Biomedical Research Center
NCT01787617
Worksite Nutrition Study
Physicians Committee for Responsible Medicine
NCT00481897
Effect of Dairy Consumption on Glycemic Control, Body Weight and Cardiovascular Risk in Patients With Type 2 Diabetes
Joslin Diabetes Center
NCT02895867
The Effects of Micronutrients in Combination With Usual Care in Type 2 Diabetes
Walter Reed National Military Medical Center
NCT01738802
Dietary Approaches to Stop Hypertension for Diabetes
Johns Hopkins University
NCT04286555
The Health Influences of Puberty (HIP) Study
University of Colorado, Denver
NCT01775813
Randomized Trial to Evaluate the Effectiveness of Nurse Case Management
Johns Hopkins University
NCT00295256
Partners in Care Diabetes Self-management Intervention
University of Hawaii
NCT01235429
Evaluation of a Digital Diabetes Self-Management Education and Support Program
Omada Health
NCT05368454
Progression and Etiology of Cortical Porosity in Diabetic Bone Disease
University of California, San Francisco
NCT04208230
Pharmacokinetic Study of Vildagliptin in Patients With Renal Impairment
Novartis
NCT00567047
Effects of Nasulin Versus Placebo on Blood Glucose Control in Patient Volunteers With Type 2 Diabetes Mellitus
CPEX Pharmaceuticals
NCT00850096
Vitamin D Supplementation on Cardiovascular Risk Factors
Florida International University
NCT01412710
Pilot RCT Evaluating Clinical Outcomes of Using Undermyfork Mobile App With Dexcom G7
Scripps Whittier Diabetes Institute
NCT06501612
Social Support Intervention for Older Adults With T2DM
Brittany L Smalls
NCT04568486
Medical Nutrition Therapy and Diabetes Self-Management Education for People With Disabilities
University of Alabama at Birmingham
NCT06049225
Diabetes Group Prenatal Care
Washington University School of Medicine
NCT02444325
A Comparison of SLx-4090 in Combination With Metformin Versus Metformin Therapy Alone in Patients With Type 2 Diabetes
Response Pharmaceuticals
NCT00871936
Food as Medicine: A Quasi-Randomized Control Trial of Healthy Foods for Chronic Disease Management
Cleveland Clinic Akron General
NCT05174078
Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes
Johns Hopkins Bloomberg School of Public Health
NCT00831194
Pistachios Blood Sugar Control, Heart and Gut Health
Penn State University
NCT04056208
Treatment Burden Screening Questionnaire Pilot Study
University of Minnesota
NCT05870202
Effects of Insulin in Perceived Mood Symptoms in Patients With Type 2 Diabetes
Eli Lilly and Company
NCT00191178
Effect of Pioglitazone on TIMP-3 and TACE in Type 2 Diabetes
The University of Texas Health Science Center at San Antonio
NCT01223196
Improving Diabetes Outcomes Through Lifestyle Change (IDOLc)Study
Massachusetts General Hospital
NCT01665989
The Effects of Anti-Inflammatory Treatment on Insulin Resistance in Healthy Volunteers
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00339833
The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
Loma Linda University
NCT01211717
The Impact of Food on Blood Sugar in People With Type 2 Diabetes
HealthPartners Institute
NCT01237314
Antioxidant Treatment of Type 2 Diabetes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00609102
Exercise and Pioglitazone for HIV-Metabolic Syndromes
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00639457
Quantitative in Vivo Biomarkers of Oxidative Stress in Diabetes
In-Young Choi, Ph.D.
NCT00845130
Effect of Saxagliptin on EPCs as a Cellular Biomarker for Evaluating Endothelial Dysfunction in Early T2DM Patients
George Washington University
NCT02024477
Effect of Glycemic Variability on Autonomic Tone in Hospitalized Patients With Type 2 Diabetes
Kathleen Dungan
NCT01409239
Taking Action: a Care for Type 2 Diabetes Intervention for Couples
Carnegie Mellon University
NCT04014582
The VALIDATE-D Study
Brigham and Women's Hospital
NCT01635062
Exercise and Type 2 Diabetes: Gender and Endothelial Function
University of Colorado, Denver
NCT01993121
The Metabolic Effects of Short-term Walnut Consumption in Subjects With the Metabolic Syndrome
Christos Mantzoros
NCT00525629
Examination of the Anti-inflammatory and Insulin Sensitizing Properties of Doxycycline in Humans
University of California, San Diego
NCT01375491
Methylglyoxal Evaluation in Humans
University of Kansas Medical Center
NCT05350553
Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of BMS-686117 in Subjects With Type 2 Diabetes
Bristol-Myers Squibb
NCT00508287
The Effect of 4 Weeks of L-Citrulline Supplementation on Macro- and Microvascular Function in Type 2 Diabetes
Texas Tech University
NCT06016478
Barriers to Physical Activity in People With Type 2 Diabetes
University of Colorado, Denver
NCT01701570
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 21 |
| Phase 2 | 21 |
| Phase 3 | 34 |
| Phase 4 | 22 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Type 2 Diabetes right now
103 recruiting of 289 indexed (36% open).
Phase mix: 56 late (III/IV) vs 42 early (I/II) (balanced across stages).
Top sponsor: Eli Lilly and Company (20 trials), 9 others listed. 50 shown below, recruiting first. #30 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Type 2 Diabetes?
PlainTrial tracks 289 US clinical trials for Type 2 Diabetes, of which 103 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Type 2 Diabetes?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.