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Thyroid Cancer
Open-data reference.
48 US clinical trials · 25 currently recruiting
Active & Recent Trials
Integrated Cancer Repository for Cancer Research
University of Nebraska
NCT02012699
Studies on Tumors of the Thyroid
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT00001160
Environmental Factors and Thyroid Cancer
Icahn School of Medicine at Mount Sinai
NCT05172921
Global Real World Data in Patients With Advanced Thyroid Cancer on Standard of Care and Specialized Interventions- Registry of Oncologic Outcomes With Testing and Treatment.
M.D. Anderson Cancer Center
NCT06507878
Use of a Decision Aid to Resolve Uncertainty About Radioactive Iodine Treatment in Patients With Intermediate Risk Thyroid Cancer
Georgetown University
NCT06980103
Improving Care for Rural Patients With Solid Tumors
University of Colorado, Denver
NCT04916990
A Study to Learn About the Study Medicine Called PF-07799933 in People With Advanced Solid Tumors With BRAF Alterations.
Pfizer
NCT05355701
Hereditary Risk Factors for Thyroid Cancer
Dana-Farber Cancer Institute
NCT02747888
New MRI Biomarkers in Head and Neck Cancers
Memorial Sloan Kettering Cancer Center
NCT03483337
A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors
Pfizer
NCT05538130
A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT05733013
Artificial Tears to Prevent Nasolacrimal Duct Obstruction in Patients Treated With Radioactive Iodine for Thyroid Cancer
Vanderbilt University Medical Center
NCT05999630
SLV-154 Treatment of Metastatic Solid Tumors
Solve Therapeutics
NCT06771219
Comparison of I-124 PET/CT for the Diagnosis of Thyroid Cancer
Thomas Hope
NCT06961084
Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery
Thomas Jefferson University
NCT06918223
I-124 PET/CT Imaging and Dosimetry for RAI-Naïve or Refractory Thyroid Cancer
Miami Cancer Research Center
NCT06443866
Zanzalintinib for the Treatment of Advanced Thyroid Cancer Before Surgery
M.D. Anderson Cancer Center
NCT06959511
Lenvatinib 24 mg/Day Versus 10 mg/Day to Treat Symptomatic or Progressive Radioactive Iodine Resistant (RAIR) Differentiated Thyroid Cancer (DTC)
Washington University School of Medicine
NCT07092514
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03841617
Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC
Massachusetts General Hospital
NCT05668962
A Study of Avutometinib and Defactinib in People With Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT06007924
TRAIL Study: Feasibility and Pilot
Dartmouth-Hitchcock Medical Center
NCT06220656
XL092 and Cemiplimab in BRAF WT Thyroid Cancer
UNC Lineberger Comprehensive Cancer Center
NCT06902376
Brodalumab in the Treatment of Immune-Related Adverse Events
Brian Henick, MD
NCT06673329
Personalized Treatment in Thyroid Disorders
Johns Hopkins University
NCT03517579
Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial
Brigham and Women's Hospital
NCT07255482
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health
University of Alabama at Birmingham
NCT04000880
Measuring Patient Expectations for Thyroid Surgery
Memorial Sloan Kettering Cancer Center
NCT01412762
A Study of Optical Imaging With Light From Radiotracers in Cancer Patients
Memorial Sloan Kettering Cancer Center
NCT03484884
TH1902 in Patients With Advanced Solid Tumors
Theratechnologies
NCT04706962
Pembrolizumab With Chemotherapy for Poorly Chemo-responsive Thyroid and Salivary Gland Tumors
University of Chicago
NCT03360890
Evaluating the Combination of Everolimus and Sorafenib in the Treatment of Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT01141309
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
The Cleveland Clinic
NCT04495985
Vemurafenib Neoadjuvant Trial in Locally Advanced Thyroid Cancer
M.D. Anderson Cancer Center
NCT01709292
PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT04544111
Study of Cemiplimab Combined With Dabrafenib and Trametinib in People With Anaplastic Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT04238624
Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer
Stanford University
NCT05119296
RAI Plus Immunotherapy for Recurrent/Metastatic Thyroid Cancers
Memorial Sloan Kettering Cancer Center
NCT03215095
Laser Ablation of Papillary Thyroid Microcarcinoma
Memorial Sloan Kettering Cancer Center
NCT04623801
A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer
Dana-Farber Cancer Institute
NCT02657551
Study of PET Imaging With 18F-TFB in Patients With Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT03196518
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Trial of Lenvatinib (E7080) in 131I-Refractory Differentiated Thyroid Cancer (DTC)
Eisai
NCT01321554
Efficacy of XL184 (Cabozantinib) in Advanced Medullary Thyroid Cancer
Exelixis
NCT00704730
Decision Making and Psychological Outcomes in Low-Risk Papillary Thyroid Cancer
Memorial Sloan Kettering Cancer Center
NCT03300284
Molecular Testing to Direct Extent of Initial Thyroid Surgery
University of Pittsburgh
NCT02947035
Effect of Childhood Radioiodine Therapy on Salivary Function
Boston Children's Hospital
NCT02375451
Study of Irofulven Plus Capecitabine in Patients With Advanced Thyroid Cancer
Eisai
NCT00124527
Energy Metabolism in Thyroidectomized Patients
Virginia Commonwealth University
NCT04782856
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 7 |
| Phase 2 | 17 |
| Phase 3 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Thyroid Cancer Trial Landscape
ClinicalTrials.gov lists 48 US studies indexed under Thyroid Cancer, and 25 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Thyroid Cancer shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 24 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Thyroid Cancer is led by Memorial Sloan Kettering Cancer Center with 12 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 48 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Thyroid Cancer?
PlainTrial tracks 48 US clinical trials for Thyroid Cancer, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Thyroid Cancer?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.