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NCT06673329 · ClinicalTrials.gov registry record · Phase 1

Brodalumab in the Treatment of Immune-Related Adverse Events

A Phase 1 study of Breast Cancer and Lung Cancer, sponsored by Brian Henick, MD.

Recruiting
Registry status
Phase 1
Development phase
11
Enrollment target
1
Study location

NCT06673329 is a Phase 1 study of Breast Cancer and Lung Cancer that is actively recruiting participants, run by Brian Henick, MD. The registered enrollment target is 11 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06673329, a Phase 1 study of Breast Cancer and Lung Cancer, is actively recruiting participants, sponsored by Brian Henick, MD.

RECRUITING
Registry status
Phase 1
Development phase
11 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to test the safety and effectiveness of using brodalumab in patients who develop side effects from cancer immune therapy. Immune-related side effects are due to activation of the immune system in patients who previously received immunotherapy and the goal of this study is to help better control these side effects. Brodalumab is often used to treat patients with autoimmune diseases (diseases where the immune system is activated against normal organs) and safe doses and treatment schedules have been determined in these patients. Immune-related side effects appear to closely mirror these autoimmune conditions. Brodalumab has not been approved by the United States Food and Drug Administration (FDA) for use in immunotherapy side effects but it has been approved for treatment of autoimmune conditions.

Interventions

  • DRUG Brodalumab
  • RADIATION CT scan

Study Locations (1)

New York

  • Columbia University Irving Medical Center - New York

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2025-03-11
Est. Completion 2026-11
Phase Phase 1

Sponsor

Brian Henick, MD

2 total trials

What the Registry Record Tells You About NCT06673329

The ClinicalTrials.gov registry entry for NCT06673329 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (100% lower). The listed sponsor is Brian Henick, MD, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Brodalumab is the first listed.

NCT06673329 reports 1 study location spanning 1 distinct geographic area - top geographies include New York.

Frequently Asked Questions

What is clinical trial NCT06673329 about?

NCT06673329 is a clinical study titled "Brodalumab in the Treatment of Immune-Related Adverse Events". The purpose of this study is to test the safety and effectiveness of using brodalumab in patients who develop side effects from cancer immune therapy. Immune-related side effects are due to activation of the immune system in patients who previously received immunotherapy and the goal of this study i...

What is the current status of trial NCT06673329?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2025-03-11. Estimated completion is 2026-11.

What conditions does trial NCT06673329 study?

This clinical trial studies the following conditions: Breast Cancer, Lung Cancer, Pancreatic Cancer, Esophageal Cancer, Colon Cancer.

What interventions are being tested in trial NCT06673329?

The interventions under investigation include: Brodalumab (DRUG), CT scan (RADIATION).

Who is sponsoring clinical trial NCT06673329?

This trial is sponsored by Brian Henick, MD, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06673329 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.