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Amblyopia clinical trials
Every US clinical trial registered for Amblyopia — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
25 US clinical trials · 13 currently recruiting
The research picture
Amblyopia has 25 registered US clinical trials, 13 of them open to new participants right now — about 52% of the total.
- 13
- recruiting participants now
- 52%
- of trials open to enrollment
- 11
- in Phase 3–4 (later-stage)
- 9
- top sponsor: Jaeb Center for Health Research
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
Jaeb Center for Health Research
NCT04378790
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Luminopia
NCT06429280
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Jaeb Center for Health Research
NCT06524882
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
Jaeb Center for Health Research
NCT06380517
Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games
Nova Southeastern University
NCT05522972
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
The Cleveland Clinic
NCT04310241
Binocular Amblyopia Treatment
Retina Foundation of the Southwest
NCT03288948
Patch-free Occlusion Therapy
Retina Foundation of the Southwest
NCT05440448
Noninvasive Brain Stimulation in Adult Amblyopia
Midwestern University
NCT06712849
Video Treatment for Amblyopia
Retina Foundation of the Southwest
NCT05439200
OCT Eccentric Fixation and Amblyopia in Children
State University of New York College of Optometry
NCT05714449
Amblyopia Treatment for Children Aged 8 to 12 Years
Retina Foundation of the Southwest
NCT07281742
Novel Amblyopia Treatment With Virtual Reality Games
Marjean Ku
NCT06049459
Binocular iPad Sub-Study
Retina Foundation of the Southwest
NCT02365090
Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia
Jaeb Center for Health Research
NCT00000170
Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children
Jaeb Center for Health Research
NCT00091923
Gocheck Kids vs. Welch Allyn Spot Vision Screener
Yale University
NCT04321538
Trial Comparing Part-time Versus Minimal-time Patching for Moderate Amblyopia
Jaeb Center for Health Research
NCT00094679
Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia
Jaeb Center for Health Research
NCT00094744
Levodopa for the Treatment of Residual Amblyopia
Jaeb Center for Health Research
NCT01190813
A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
Barron Associates
NCT03066063
Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
Jaeb Center for Health Research
NCT00944710
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
Rebiscan
NCT01706991
Amblyopia (Lazy Eye) Treatment Study
National Eye Institute (NEI)
NCT00001864
Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia
Dennis Levi
NCT03109314
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 10 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Amblyopia Trial Landscape
ClinicalTrials.gov lists 25 US studies indexed under Amblyopia, and 13 of those are currently open to recruitment — roughly 52% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Amblyopia shows 11 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Amblyopia is led by Jaeb Center for Health Research with 9 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Amblyopia?
PlainTrial tracks 25 US clinical trials for Amblyopia, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Amblyopia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.