Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Amblyopia: later-stage trial registry
13 of 25 indexed Amblyopia trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #652 of 28,707 conditions by registered trial count.
25 US clinical trials · 13 currently recruiting · #652 of 28,707 conditions by registered trial count
Amblyopia: 25 US clinical trials tracked, 13 recruiting.
Amblyopia is the subject of 25 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Jaeb Center for Health Research, running 9 of these trials.
Enrollment posture brief
Registry condition amblyopia
OPEN 13 | RECR 52% | LATE 11 | EARLY 0 | RANK #652 | SPON 9
Volume-matched condition peers
Nearest open-share peer: Basal Cell Carcinoma (52% recruiting · 25 trials)
Amblyopia lists 13 open slots (52% of 25 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Amblyopia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Amblyopia is recruiting above its size-band peers.
13 of 25 indexed trials (52%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Amblyopia research.
Jaeb Center for Health Research accounts for 9 of 25 trials (36%). 13 distinct sponsors appear on at least one study for this condition label.
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Typical Amblyopia enrolment sits around 120 participants.
Median target enrolment is 120 among the 25 trials that report a genuine target (sentinel values excluded). 12 of those (48%) plan for fewer than 100 participants.
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Amblyopia research is mostly interventional.
21 interventional and 4 observational studies make up this index (84% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
25 total, page 1 of 1
A Randomized Trial to Evaluate Sequential vs Simultaneous Patching
Jaeb Center for Health Research
NCT04378790
Clinical Data Registry of Amblyopia Patients on Luminopia Treatment
Luminopia
NCT06429280
Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age
Jaeb Center for Health Research
NCT06524882
Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age
Jaeb Center for Health Research
NCT06380517
Establishing New Treatment Approaches for Amblyopia: Perceptual Learning and Video Games
Nova Southeastern University
NCT05522972
Visual Function Abnormalities in Strabismus and Amblyopia and Response to Therapy
The Cleveland Clinic
NCT04310241
Binocular Amblyopia Treatment
Retina Foundation of the Southwest
NCT03288948
Patch-free Occlusion Therapy
Retina Foundation of the Southwest
NCT05440448
Noninvasive Brain Stimulation in Adult Amblyopia
Midwestern University
NCT06712849
Video Treatment for Amblyopia
Retina Foundation of the Southwest
NCT05439200
OCT Eccentric Fixation and Amblyopia in Children
State University of New York College of Optometry
NCT05714449
Amblyopia Treatment for Children Aged 8 to 12 Years
Retina Foundation of the Southwest
NCT07281742
Novel Amblyopia Treatment With Virtual Reality Games
Marjean Ku
NCT06049459
Binocular iPad Sub-Study
Retina Foundation of the Southwest
NCT02365090
Occlusion Versus Pharmacologic Therapy for Moderate Amblyopia
Jaeb Center for Health Research
NCT00000170
Trial to Evaluate 2 Hours of Daily Patching for Amblyopia in Children
Jaeb Center for Health Research
NCT00091923
Gocheck Kids vs. Welch Allyn Spot Vision Screener
Yale University
NCT04321538
Trial Comparing Part-time Versus Minimal-time Patching for Moderate Amblyopia
Jaeb Center for Health Research
NCT00094679
Trial Comparing Part-time Versus Full-time Patching for Severe Amblyopia
Jaeb Center for Health Research
NCT00094744
Levodopa for the Treatment of Residual Amblyopia
Jaeb Center for Health Research
NCT01190813
A New Approach to Vision Therapy Based on Naturalistic 3-D Computer Gaming
Barron Associates
NCT03066063
Augmenting Atropine Treatment for Amblyopia in Children 3 to < 8 Years Old
Jaeb Center for Health Research
NCT00944710
Amblyopia and Strabismus Detection Using a Pediatric Vision Scanner
Rebiscan
NCT01706991
Amblyopia (Lazy Eye) Treatment Study
National Eye Institute (NEI)
NCT00001864
Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia
Dennis Levi
NCT03109314
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 10 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Amblyopia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Amblyopia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Amblyopia page
25 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 13 Amblyopia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Jaeb Center for Health Research sponsors the most Amblyopia trials on record, review their full trial history before evaluating a specific study. See Jaeb Center for Health Research's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Amblyopia condition card totals 25 registered trials; most-linked intervention Eye patch; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.