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NCT04829071 · ClinicalTrials.gov registry record · Early Phase 1

Cognition and Motor Learning Post-stroke

A Early Phase 1 study of Stroke and CVA (Cerebrovascular Accident), sponsored by University of Southern California.

Recruiting
Registry status
Early Phase 1
Development phase
65
Enrollment target
1
Study location

NCT04829071: Recruiting Early Phase 1 study of Stroke and CVA (Cerebrovascular Accident), sponsored by University of Southern California.

NCT04829071 is a Early Phase 1 study of Stroke and CVA (Cerebrovascular Accident) that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 65 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04829071, a Early Phase 1 study of Stroke and CVA (Cerebrovascular Accident), is actively recruiting participants, sponsored by University of Southern California.

RECRUITING
Registry status
Early Phase 1
Development phase
65 participants
Enrollment target
1
Study location

Study Summary

This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological assessments, and brain imaging techniques to determine the impact of post-stroke cognitive impairment severity on two forms of motor learning (explicit and implicit) and examine the role of the dorsolateral prefrontal cortex in the relationship between cognition and explicit motor learning. Ultimately, this work may lead to the development of a more comprehensive, effective treatment approach to improve walking dysfunction in older adults post-stroke.

Primary Outcome

characterized as a comparison between the right and left step lengths; captured to quantify change in performance with biofeedback or split belt walking

Interventions

  • BEHAVIORAL Explicit motor learning
  • BEHAVIORAL Implicit motor learning

Study Locations (1)

California

  • Center for Health Professions - Los Angeles

Trial Details

FieldValue
Enrollment Target 65 participants
Start Date 2023-01-16
Est. Completion 2026-12-14
Phase Early Phase 1
University of Southern California

617 total trials

What NCT04829071 shows while recruiting

NCT04829071 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 65 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).

The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Explicit motor learning is the first listed.

NCT04829071 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT04829071 about?

NCT04829071 is a clinical study titled "Cognition and Motor Learning Post-stroke". This project seeks to determine how post-stroke cognitive impairment moderates motor learning during walking in older adults with chronic stroke and identify brain structural markers that mediate this relationship. The chosen experimental design integrates biomechanical analyses, neuropsychological ...

What is the current status of trial NCT04829071?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 65 participants. The study started on 2023-01-16. Estimated completion is 2026-12-14.

What conditions does trial NCT04829071 study?

This clinical trial studies the following conditions: Stroke, CVA (Cerebrovascular Accident).

What interventions are being tested in trial NCT04829071?

The interventions under investigation include: Explicit motor learning (BEHAVIORAL), Implicit motor learning (BEHAVIORAL).

Who is sponsoring clinical trial NCT04829071?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04829071 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04829071's enrollment target sits among peer trials

65 195th of 454 higher than 258 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04829071, the US trial registry maintained by the National Library of Medicine. NCT04829071 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.