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NCT06404268 · ClinicalTrials.gov registry record · Phase 1
Facilitating Neuroplastic Changes of Acute Stroke Survivors
A Phase 1 study of Stroke, sponsored by University of Maryland, Baltimore.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 68
- Enrollment target
- 2
- Study locations
NCT06404268: Recruiting Phase 1 study of Stroke, sponsored by University of Maryland, Baltimore.
NCT06404268 is a Phase 1 study of Stroke that is actively recruiting participants, run by University of Maryland, Baltimore. The registered enrollment target is 68 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06404268, a Phase 1 study of Stroke, is actively recruiting participants, sponsored by University of Maryland, Baltimore.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 68 participants
- Enrollment target
- 2
- Study locations
Study Summary
This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-stroke including patients who are paralyzed with no motor output. The early acute stroke rehabilitation device will be evaluated in this clinical trial.
Primary Outcome
The Fugl-Meyer Lower Extremity (FMLE) assessment is a measure of lower extremity (LE) motor and sensory impairments. The FMLE scale ranges from 0 to 34, with higher scores indicating better motor function.
Conditions Studied
Interventions
- DEVICE Motor relearning training
- DEVICE Passive stretching
- DEVICE Gamed-based active movement training
- DEVICE Passive movement
- DEVICE Active movement training
Study Locations (2)
Maryland
- University of Maryland Baltimore - Baltimore
- UMROI - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 68 participants |
| Start Date | 2025-06-01 |
| Est. Completion | 2028-08-31 |
| Phase | Phase 1 |
What NCT06404268 shows while recruiting
NCT06404268 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 68 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 5 interventions - of which Motor relearning training is the first listed.
NCT06404268 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06404268 about?
NCT06404268 is a clinical study titled "Facilitating Neuroplastic Changes of Acute Stroke Survivors". This project will develop a wearable rehabilitation robot suitable for in-bed acute stage rehabilitation. It involves robot-guided motor relearning, passive and active motor-sensory rehabilitation early in the acute stage post-stroke including patients who are paralyzed with no motor output. The ear...
What is the current status of trial NCT06404268?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 68 participants. The study started on 2025-06-01. Estimated completion is 2028-08-31.
What conditions does trial NCT06404268 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT06404268?
The interventions under investigation include: Motor relearning training (DEVICE), Passive stretching (DEVICE), Gamed-based active movement training (DEVICE), Passive movement (DEVICE), Active movement training (DEVICE).
Who is sponsoring clinical trial NCT06404268?
This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06404268 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06404268's enrollment target sits among peer trials
68 191st of 454 higher than 262 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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