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NCT06458153 · ClinicalTrials.gov registry record · NA
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
A NA study of Stroke and Cerebellum, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT06458153: Recruiting NA study of Stroke and Cerebellum, sponsored by University of Pittsburgh.
NCT06458153 is a NA study of Stroke and Cerebellum that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 100 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06458153, a NA study of Stroke and Cerebellum, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's sensory systems show changes in their activity related to speech? 2. To what extent do these regions help listeners detect and correct speech errors? 3. What is the role of the cerebellum (a part of the brain in the back of the head) in these activities? Participants will be asked to complete several experimental sessions involving behavioral speech and related tests and non-invasive brain imaging using electroencephalography (EEG) and functional magnetic resonance imaging (fMRI).
Primary Outcome
The dependent variables (across voxels) are blood oxygenated level dependent fMRI measurements made during task performance. We will contrast measured activations in regions of interest for the LISTEN-SELF vs. PRODUCE and LISTEN-OTHER vs. PRODUCE conditions. Encoding models will predict activity in regions-of-interest (ROIs) based on a set of speech features.
Conditions Studied
Interventions
- BEHAVIORAL Neural responses to speech functional localizer
- BEHAVIORAL Neural responses to silent articulation
- BEHAVIORAL Neural responses to self vs. externally generated speech
- BEHAVIORAL Event-related potentials for speech
- BEHAVIORAL Neural responses to induced speech errors
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2025-05-27 |
| Est. Completion | 2028-07 |
| Phase | NA |
What NCT06458153 shows while recruiting
NCT06458153 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 5 interventions - of which Neural responses to speech functional localizer is the first listed.
NCT06458153 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT06458153 about?
NCT06458153 is a clinical study titled "Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke". The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes. The main questions it aims to answer are: 1. What regions of the brain's...
What is the current status of trial NCT06458153?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-05-27. Estimated completion is 2028-07.
What conditions does trial NCT06458153 study?
This clinical trial studies the following conditions: Stroke, Cerebellum.
What interventions are being tested in trial NCT06458153?
The interventions under investigation include: Neural responses to speech functional localizer (BEHAVIORAL), Neural responses to silent articulation (BEHAVIORAL), Neural responses to self vs. externally generated speech (BEHAVIORAL), Event-related potentials for speech (BEHAVIORAL), Neural responses to induced speech errors (BEHAVIORAL).
Who is sponsoring clinical trial NCT06458153?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06458153 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06458153's enrollment target sits among peer trials
100 135th of 454 higher than 309 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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