Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07050355 · ClinicalTrials.gov registry record · NA
Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking
A NA study of Stroke and Depression - Major Depressive Disorder, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 96
- Enrollment target
- 2
- Study locations
NCT07050355 is a NA study of Stroke and Depression - Major Depressive Disorder that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 96 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 2 study locations across 2 states.
The verdict
NCT07050355, a NA study of Stroke and Depression - Major Depressive Disorder, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 96 participants
- Enrollment target
- 2
- Study locations
Study Summary
Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD). Investigators propose to determine the efficacy of combining two known anti-depressant treatments shown to be effective in non-stroke depression, aerobic exercise (AEx) and repetitive transcranial magnetic stimulation (rTMS), on post-stroke depressive symptoms. This project is based on the idea that depression negatively affects the potential for the brain to adapt in response to treatment such that rehabilitation may not produce the same changes that it does in non-depressed individuals. Investigators believe that effective treatment for PSD will result in a virtuous cycle whereby reducing depression enhances response to rehabilitation, thereby facilitating functional gains. That is, effectively treating depression will enable individuals to better recover from stroke.
Conditions Studied
Interventions
- DEVICE rTMS
- BEHAVIORAL AEx
Study Locations (2)
North Carolina
- Duke University School of Medicine - Durham
South Carolina
- Medical University of South Carolina - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2024-11-01 |
| Est. Completion | 2029-08-31 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07050355
The ClinicalTrials.gov registry entry for NCT07050355 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which rTMS is the first listed.
NCT07050355 reports 2 study locations spanning 2 distinct geographic areas - top geographies include North Carolina, South Carolina.
Frequently Asked Questions
What is clinical trial NCT07050355 about?
NCT07050355 is a clinical study titled "Combining rTMS & Aerobic Exercise to Treat Depression and Improve Post-Stroke Walking". Investigators primary aim is to carry out a two-site, randomized, double-blind, sham-controlled, phase II trial to systematically examine the potential for aerobic exercise (AEx) to enhance the anti-depressant benefits of rTMS in individuals with post-stroke depression (PSD). Investigators propose ...
What is the current status of trial NCT07050355?
This trial is currently recruiting. It is a NA study. The enrollment target is 96 participants. The study started on 2024-11-01. Estimated completion is 2029-08-31.
What conditions does trial NCT07050355 study?
This clinical trial studies the following conditions: Stroke, Depression - Major Depressive Disorder, Walking Impairment.
What interventions are being tested in trial NCT07050355?
The interventions under investigation include: rTMS (DEVICE), AEx (BEHAVIORAL).
Who is sponsoring clinical trial NCT07050355?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07050355 being conducted?
This trial has 2 study locations across North Carolina, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Tracking a Tactile Signal Along the Nervous System
RECRUITING · NA
-
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
RECRUITING · NA
-
Strategy Training for Individuals With Unilateral Neglect
RECRUITING · NA
-
Weight Loss and ExeRcise
RECRUITING · NA
-
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
RECRUITING · NA
-
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
RECRUITING · NA
Explore more on PlainTrial
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.