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ClinicalTrials.gov 218 recruiting now early-phase tilt #9 of 28,963 conditions

Stroke: early-phase trial registry

218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #9 of 28,963 conditions by registered trial count.

456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count

Stroke: 456 US clinical trials tracked, 218 recruiting.

Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.

Open enrollment, early-phase tilt

Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.

218
recruiting participants now
48%
of trials open to enrollment
16
in Phase 3-4 (later-stage)
27
top sponsor: VA Office of Research and Development

Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Stroke is recruiting above its size-band peers.

    218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stroke trials is spread across many organizations.

    VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.

  3. Most Stroke trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.

  4. Stroke research is mostly interventional.

    385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 135Phase 234Phase 37Phase 49

Open and recent trials

456 total, page 1 of 10

RECRUITING 3,892,063 participants

Get With the Guidelines-Stroke Registry

American Heart Association

NCT02693223

RECRUITING 60,000 participants

Stroke Recovery Initiative - Registry for Stroke Research Studies

University of California, San Francisco

NCT03318432

RECRUITING 40,000 participants

Stroke Thrombectomy and Aneurysm Registry

Medical University of South Carolina

NCT04994756

RECRUITING Phase 4 3,500 participants

International Care Bundle Evaluation in Cerebral Hemorrhage Research

Region Skane

NCT06429332

RECRUITING Phase 3 3,200 participants

Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

Icahn School of Medicine at Mount Sinai

NCT04045665

RECRUITING 3,000 participants

Transitions of Care for Stroke Patients

Kiwon Lee MD

NCT06011720

RECRUITING Phase 4 2,270 participants

Anticoagulation for Stroke Prevention In Patients With Recent Episodes of Atrial Fibrillation Occurring Transiently With Stress

Population Health Research Institute

NCT03968393

RECRUITING NA 1,600 participants

The CONFORM Pivotal Trial

Conformal Medical

NCT05147792

RECRUITING Phase 2 1,164 participants

Minocycline in Stroke Study at Maimonides

Joyce Chen

NCT07237048

RECRUITING 1,060 participants

Treatment With Endovascular Intervention for STroke Patients With Existing Disability

University of Cincinnati

NCT05911568

RECRUITING 1,000 participants

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

State University of New York at Buffalo

NCT00682695

RECRUITING 1,000 participants

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

Zeenat Qureshi Stroke Institute

NCT06402968

RECRUITING NA 764 participants

Human-like Robotic Controllers for Enhanced Motor Learning

Shirley Ryan AbilityLab

NCT04578665

RECRUITING Phase 2 728 participants

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

DiaMedica Therapeutics

NCT05065216

RECRUITING 657 participants

Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

University of Cincinnati

NCT05338697

RECRUITING NA 636 participants

GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

W.L.Gore & Associates

NCT03821129

RECRUITING 588 participants

Beacon Tip Sizing Catheter and Slip-Cath Beacon Tip Catheter Study

Cook Research Incorporated

NCT06986954

RECRUITING 581 participants

CoMind Early Feasibility Study

CoMind Technologies Limited

NCT06368648

RECRUITING NA 546 participants

Reducing Blood Pressure in Patients With High Cardiovascular Risk

University of Southern California

NCT05937685

RECRUITING NA 520 participants

Compass 3: A Novel Transition Program to Reduce Disability After Stroke

Washington University School of Medicine

NCT07069660

RECRUITING NA 500 participants

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

University of South Carolina

NCT05370014

RECRUITING NA 500 participants

Neurologic Stem Cell Treatment Study

MD Stem Cells

NCT02795052

RECRUITING 450 participants

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

National Institute of Neurological Disorders and Stroke (NINDS)

NCT06615973

RECRUITING 424 participants

Cognition and Imaging With Tigertriever

Rapid Medical

NCT05531461

RECRUITING 400 participants

Inpatient Stroke Recovery Using Sensors

Shirley Ryan AbilityLab

NCT04219670

RECRUITING NA 388 participants

Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence

University of Tennessee

NCT06374277

RECRUITING NA 360 participants

Optimizing the Prehospital Use of Stroke Systems of Care-Reacting to Changing Paradigms-Implementation (OPUS-i)

Temple University

NCT06530693

RECRUITING 350 participants

StrokeCog-BBB to Study Cognitive Outcomes Following Stroke

Stanford University

NCT06116630

RECRUITING NA 350 participants

Neurocognitive Mechanisms of Sentence Production Impairment in Aphasia

University of Maryland, College Park

NCT06405594

RECRUITING 300 participants

ReadMap: Reading in Stroke Alexia and Typical Aging

Georgetown University

NCT06700005

RECRUITING 300 participants

Diagnostic Performance Study of the EMVision Emu™ Brain Scanner in the Detection of Intracranial Hemorrhage in Suspected Stroke Patients

EMVision Medical Devices

NCT06999122

RECRUITING 300 participants

Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis- Magnetic Resonance Imaging

Yale University

NCT05907629

RECRUITING NA 288 participants

A Closed Loop Neural Activity Triggered Stroke Rehabilitation Device

University of Wisconsin, Madison

NCT02098265

RECRUITING NA 275 participants

SDOH-Homecare Intervention Focus Team (SHIFT) Trial to Improve Stroke Outcomes

Columbia University

NCT06397937

RECRUITING 250 participants

C-STAR Movement Database

Shirley Ryan AbilityLab

NCT05471375

RECRUITING 250 participants

Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis

University of California, Los Angeles

NCT05518305

RECRUITING 240 participants

Traumatic Brain Injury and Stroke Long Term Outcome

Centre for Neuro Skills

NCT03399929

RECRUITING NA 220 participants

Efficacy and Sustainability of a Carepartner-Integrated Telerehabilitation Program for Persons With Stroke

Emory University

NCT06655402

RECRUITING NA 202 participants

Telerehabilitation In The Home After Stroke

University of California, Los Angeles

NCT06682429

RECRUITING NA 202 participants

Pilot/Pivotal Study of DBS+Rehab After Stroke

Enspire DBS Therapy

NCT05701280

RECRUITING 200 participants

The SLEEPR Study: SLEep Effects on Post-stroke Rehabilitation

State University of New York - Upstate Medical University

NCT05012605

RECRUITING NA 200 participants

Pharmacogenomics in Stroke: Feasibility of CYP2C19 Testing

University of Alabama at Birmingham

NCT06943586

RECRUITING 199 participants

The Beneficial Effects of Naps on Motor Learning

National Institute of Neurological Disorders and Stroke (NINDS)

NCT04312126

RECRUITING NA 156 participants

HIT-Stroke Trial 2

University of Cincinnati

NCT06268041

RECRUITING NA 150 participants

Cardiac Rehabilitation of Stroke Survivors (SRP-CROSS)

Hackensack Meridian Health

NCT05651945

RECRUITING 150 participants

Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future

International Consortium of Circulatory Assist Clinicians

NCT06039176

RECRUITING NA 150 participants

Locomotor Recovery and Compensation Post-stroke (LRC)

Indiana University

NCT05081713

RECRUITING NA 150 participants

Testing the Effectiveness of a Novel Intervention to Improve Medication Adherence in Stroke Survivors

Massachusetts General Hospital

NCT07414732

RECRUITING NA 135 participants

Language Processing and TMS

Medical College of Wisconsin

NCT05425615

RECRUITING NA 130 participants

EMPOWER: Effects of Weight Loss and Exercise Post-stroke

Medical University of South Carolina

NCT05901675

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Phase Distribution

PhaseTrial count
Phase 1 35
Phase 2 34
Phase 3 7
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Stroke right now

218 recruiting of 456 indexed (48% open).

Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).

Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Stroke?

PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stroke?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.