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NCT03843463 · ClinicalTrials.gov registry record · Phase 2
Escitalopram and Language Intervention for Subacute Aphasia
A Phase 2 study of Stroke and Aphasia, sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 88
- Enrollment target
- 3
- Study locations
NCT03843463: Recruiting Phase 2 study of Stroke and Aphasia, sponsored by Johns Hopkins University.
NCT03843463 is a Phase 2 study of Stroke and Aphasia that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 88 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 3 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03843463, a Phase 2 study of Stroke and Aphasia, is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 88 participants
- Enrollment target
- 3
- Study locations
Study Summary
In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post stroke period (i.e., within three months post stroke).
Primary Outcome
Number of correctly named items of 30 total items on the computerized picture naming assessment. Scores ranges from 0 to 30 with higher scores meaning better naming ability.
Interventions
- DRUG Placebo
- DRUG Escitalopram 10mg
- BEHAVIORAL Computer-delivered naming treatment
Study Locations (3)
South Carolina
- Medical University of South Carolina - Charleston
- University of South Carolina - Columbia
Maryland
- Johns Hopkins School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2021-07-18 |
| Est. Completion | 2027-01-18 |
| Phase | Phase 2 |
What NCT03843463 shows while recruiting
NCT03843463 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 88 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Stroke appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT03843463 reports a single indexed study location in South Carolina, Maryland.
Frequently Asked Questions
What is clinical trial NCT03843463 about?
NCT03843463 is a clinical study titled "Escitalopram and Language Intervention for Subacute Aphasia". In this project, the investigators will investigate the effects of a selective serotonin reuptake inhibitor (SSRI), escitalopram, on augmenting language therapy effectiveness, as measured by naming untrained pictures and describing pictures, in individuals with aphasia in the acute and subacute post...
What is the current status of trial NCT03843463?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2021-07-18. Estimated completion is 2027-01-18.
What conditions does trial NCT03843463 study?
This clinical trial studies the following conditions: Stroke, Aphasia.
What interventions are being tested in trial NCT03843463?
The interventions under investigation include: Placebo (DRUG), Escitalopram 10mg (DRUG), Computer-delivered naming treatment (BEHAVIORAL).
Who is sponsoring clinical trial NCT03843463?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03843463 being conducted?
This trial has 3 study locations across Maryland, South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03843463's enrollment target sits among peer trials
88 159th of 454 higher than 295 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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