Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04477330 · ClinicalTrials.gov registry record · NA

Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal

A NA study of Stroke, sponsored by University of Illinois at Chicago.

Recruiting
Registry status
NA
Development phase
100
Enrollment target
1
Study location

NCT04477330: Recruiting NA study of Stroke, sponsored by University of Illinois at Chicago.

NCT04477330 is a NA study of Stroke that is actively recruiting participants, run by University of Illinois at Chicago. The registered enrollment target is 100 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04477330, a NA study of Stroke, is actively recruiting participants, sponsored by University of Illinois at Chicago.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged as a promising adjuvant to conventional rehabilitation. This project focuses on the development of a long term gait rehabilitation protocol using brain stimulation to improve walking outcomes in people with stroke. The project will also aim to understand the neural mechanisms that are associated with response to the intervention.

Primary Outcome

Self-selected and fastest gait speed will be measured as the average of 3 trials of the 10-m walk test (10MWT).

Conditions Studied

Interventions

  • OTHER Transcranial direct current stimulation (tDCS)
  • OTHER Ankle motor training
  • BEHAVIORAL High intensity interval speed based treadmill training (HIISTT)

Study Locations (1)

Illinois

  • Physical Therapy - Chicago

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2020-09-01
Est. Completion 2025-12-31
Phase NA
University of Illinois at Chicago

430 total trials

What NCT04477330 shows while recruiting

NCT04477330 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).

The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 3 interventions - of which Transcranial direct current stimulation (tDCS) is the first listed.

NCT04477330 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT04477330 about?

NCT04477330 is a clinical study titled "Cortical Priming to Optimize Gait Rehabilitation in Stroke: a Renewal". Achieving functional ambulation post stroke continues to be a challenge for stroke survivors, clinicians, and researchers. In the effort to enhance outcomes of motor training, cortical priming using brain stimulation has emerged as a promising adjuvant to conventional rehabilitation. This project fo...

What is the current status of trial NCT04477330?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2020-09-01. Estimated completion is 2025-12-31.

What conditions does trial NCT04477330 study?

This clinical trial studies the following conditions: Stroke.

What interventions are being tested in trial NCT04477330?

The interventions under investigation include: Transcranial direct current stimulation (tDCS) (OTHER), Ankle motor training (OTHER), High intensity interval speed based treadmill training (HIISTT) (BEHAVIORAL).

Who is sponsoring clinical trial NCT04477330?

This trial is sponsored by University of Illinois at Chicago, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04477330 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04477330's enrollment target sits among peer trials

100 135th of 454 higher than 309 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01048281 · 100 participants

    Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

  • NCT01161199 · 100 participants

    The Use of Leukapheresis to Support HIV Pathogenesis Studies

  • NCT01327690 · 100 participants · Early Phase 1

    Mental Health in Veterans and Families After Group Therapies

  • NCT01730781 · 100 participants

    Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT04477330, the US trial registry maintained by the National Library of Medicine. NCT04477330 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.