Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

2026 data Public-data reference. official source

Pregnancy

Open-data reference.

194 US clinical trials · 77 currently recruiting

Active & Recent Trials

RECRUITING 25,000 participants

Clinical Follow-up of Pregnant Subjects Undergoing NIPT

Sequenom

NCT04595201

RECRUITING 5,000 participants

Effects of Oncological Treatment During Pregnancy on Mother and Child

University Hospital, Gasthuisberg

NCT00330447

RECRUITING NA 4,700 participants

Michigan Contraceptive Access, Research, and Evaluation Study Children: Phase 1

University of Michigan

NCT04371900

RECRUITING NA 3,000 participants

Rhode Island Community-based Maternal Support Services

Women and Infants Hospital of Rhode Island

NCT07446374

RECRUITING 2,821 participants

Healthy Start: Exploring the Fuel-mediated Programming of Neonatal Growth

University of Colorado, Denver

NCT02273297

RECRUITING NA 1,320 participants

Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

Massachusetts General Hospital

NCT06557005

RECRUITING 1,250 participants

Study of Placental Function in Healthy and Pathological Pregnancies

University of Colorado, Denver

NCT02321007

RECRUITING 1,000 participants

UCLA Perinatal Biospecimen Repository

Yalda Afshar, MD, PhD

NCT05035160

RECRUITING 1,000 participants

A Study of a Test for Postpartum Depression at Home

University of Virginia

NCT07186309

RECRUITING NA 840 participants

Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women

Duke University

NCT04985903

RECRUITING NA 795 participants

CHIME: Comparing Health Interventions for Maternal Equity

Stanford University

NCT06724172

RECRUITING 725 participants

Kesimpta (Ofatumumab) Pregnancy Registry

Novartis Pharmaceuticals

NCT05634967

RECRUITING 600 participants

A Repository to Study Host-Microbiome Interactions in Health and Disease

National Institute of Allergy and Infectious Diseases (NIAID)

NCT05656378

RECRUITING NA 600 participants

Perelel Prenatal Supplements vs. Generic Prenatal Supplements and Health of Mother and Baby (SUPPORT)

University of Pittsburgh

NCT07046845

RECRUITING NA 570 participants

Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

University of Michigan

NCT05000645

RECRUITING NA 564 participants

CGM for Management of Type 2 Diabetes in Pregnancy

University of Alabama at Birmingham

NCT06628453

RECRUITING 550 participants

External Trigeminal Nerve Stimulation for Migraine Treatment in Pregnancy

Cefaly Technology

NCT06788977

RECRUITING NA 550 participants

Better Birth Outcomes Through Technology, Education, and Reporting

Ohio State University

NCT06261398

RECRUITING 500 participants

Clinical Validation of a Predictive Test for Postpartum Depression

University of Virginia

NCT06831968

RECRUITING 500 participants

Prospective Collection of Whole Blood Specimens From RhD Negative Pregnant Women

Devyser

NCT06690099

RECRUITING 500 participants

Hemophilia A Research Program

University of Washington

NCT07414511

RECRUITING 500 participants

Pregnancies Complicated by Fetal Anomalies

University of Tennessee

NCT02505464

RECRUITING 400 participants

Assessment of Early Pregnancy MAB Completion

University of Washington

NCT06893484

RECRUITING NA 400 participants

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Emory University

NCT05910580

RECRUITING NA 400 participants

Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication

University of Maryland, College Park

NCT06053515

RECRUITING NA 384 participants

Cocooned Moms Study

InovCares Connected Comprehensive Healthcare Corporation

NCT06968650

RECRUITING NA 300 participants

Advanced Fetal Imaging - Phase II

Boston Children's Hospital

NCT02840019

RECRUITING Phase 3 300 participants

Different Medications to Induce Labor

Icahn School of Medicine at Mount Sinai

NCT06259097

RECRUITING Phase 3 300 participants

Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

Women and Infants Hospital of Rhode Island

NCT05462704

RECRUITING NA 300 participants

Pregnancy Exercise Mode Effect on Childhood Obesity

East Carolina University

NCT04805502

RECRUITING 200 participants

Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project

University of California, San Diego

NCT02103361

RECRUITING NA 200 participants

Postnatal Exercise to Activate Baby's Brown Fat

Joslin Diabetes Center

NCT07467694

RECRUITING NA 200 participants

Educational, Social Support, and Nutritional Interventions and Their Cumulative Effect on Pregnancy Outcomes and Quality of Life in Teen and Adult Women With Phenylketonuria

Emory University

NCT01659749

RECRUITING 200 participants

Longitudinal Study of Intra-Uterine Growth Restriction

University of Colorado, Denver

NCT02382601

RECRUITING NA 200 participants

Optimizing Timing of Cesarean Delivery Consent on Labor and Delivery

Duke University

NCT07117708

RECRUITING 200 participants

Maternal And Infant Antipsychotic Study

Icahn School of Medicine at Mount Sinai

NCT06049953

RECRUITING NA 180 participants

Impact of the NeuroCuple Device on Pain Management After Cesarean Delivery

Inova Health Care Services

NCT07185425

RECRUITING Early Phase 1 162 participants

Induction of Labor in Morbidly Obese Patients

University of Maryland, Baltimore

NCT06199154

RECRUITING 160 participants

Vitamin D Dynamics in Women

Cornell University

NCT02705287

RECRUITING NA 150 participants

Automated Insulin for Management of Intrapartum Glycemia

University of California, San Francis

NCT06883344

RECRUITING NA 150 participants

Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

University of Missouri-Columbia

NCT06741735

RECRUITING NA 144 participants

Healthy Mom Zone Gestational Weight Gain Management Intervention 2.0

Penn State University

NCT05807594

RECRUITING 140 participants

The Early and Late Contribution of Fasting and Postprandial Triglycerides on Newborn Subcutaneous and Intrahepatic Fat in Pregnancy

University of Colorado, Denver

NCT04394806

RECRUITING Phase 4 120 participants

Oral Iron Supplementation on Alternate Vs. Consecutive Days for Iron Deficiency Anemia in Pregnancy

Southern Illinois University

NCT06492512

RECRUITING 110 participants

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

International Maternal Pediatric Adolescent AIDS Clinical Trials Group

NCT07207876

RECRUITING NA 108 participants

Gastric Emptying of Water and Sports Drink in Labor

Beth Israel Deaconess Medical Center

NCT04229043

RECRUITING NA 100 participants

Enhancing Care & Outcomes for Patients During the First Postpartum Year

University of Maryland, Baltimore

NCT06615076

RECRUITING NA 100 participants

Impact of Patient Selected Visual Art in the Hospital Room During Antepartum Admission on Hospital Satisfaction Scores and Patient Experience

Albany Medical College

NCT06790043

RECRUITING 100 participants

Avalglucosidase Alfa Pregnancy Study

Sanofi

NCT05734521

RECRUITING 90 participants

Retinal Vascular Changes During Pregnancy

Vanderbilt University Medical Center

NCT06311617

RECRUITING 84 participants

Effects of High Altitude on AMPK Activation

University of Colorado, Denver

NCT02391519

RECRUITING 80 participants

Midwest Birth Outcomes and Indigenous American Pregnancy

Sanford Health

NCT06008561

RECRUITING 75 participants

Study of Ultomiris® (Ravulizumab) Safety in Pregnancy

Alexion Pharmaceuticals

NCT06312644

RECRUITING NA 75 participants

Understanding the Role of Doulas in Supporting People With PMADs

University of Montana

NCT05763537

RECRUITING NA 70 participants

CGM Adherence Compared to Finger-stick Glucose Monitoring in Pregnancies With Type 2 Pregestational Diabetes

Thomas Jefferson University

NCT07184775

RECRUITING NA 60 participants

Feasibility of an ADAPTive Intervention to Improve Food Security and Maternal-Child Health

Wake Forest University Health Sciences

NCT06942598

RECRUITING Phase 2 60 participants

Progesterone to Enhance the Efficacy and Success of Expectantly Managed Preterm Severe/Superimposed Preeclampsia

University of Mississippi Medical Center

NCT02989025

RECRUITING NA 60 participants

Effectiveness of Interventions to Promote Physical Activity During Pregnancy

University of Central Florida

NCT07223112

RECRUITING 60 participants

Placental Imaging Techniques

Carilion Clinic

NCT06861309

RECRUITING NA 60 participants

Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)

University of Texas at Austin

NCT07060144

RECRUITING NA 50 participants

Mitigating Response to Stressors in Pregnant Women

Nova Southeastern University

NCT06718907

RECRUITING Phase 3 50 participants

Ropivacaine and Fentanyl for Labor Epidural Initiation

University of California, San Francis

NCT07076368

RECRUITING 50 participants

Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

University of Tennessee Graduate School of Medicine

NCT06802861

RECRUITING 50 participants

Pregnancy Surveillance Program of Patients Exposed to Epidiolex/Epidyolex During Pregnancy

Jazz Pharmaceuticals

NCT06113237

RECRUITING NA 48 participants

Maternal Smoking Cessation and Pediatric Obesity Prevention

State University of New York at Buffalo

NCT03514602

RECRUITING 46 participants

Pregnant Women With and Without Crohns Disease to Explore the Role of Plastics and Toxins in Intestinal Inflammation

Icahn School of Medicine at Mount Sinai

NCT06001450

RECRUITING NA 40 participants

Prenatal Study in Healthy Pregnant Women

Perelel

NCT07226414

RECRUITING NA 40 participants

Therapeutic Omegas for Triglyceride Suppression

University of Colorado, Denver

NCT04349475

RECRUITING NA 40 participants

Substance Use in Pregnant People - Optimizing Retention in Treatment

Washington University School of Medicine

NCT07104123

RECRUITING NA 37 participants

Technology-Enhanced Therapy vs. Medication Monitoring for Buprenorphine Retention in Pregnant Persons

Medical University of South Carolina

NCT06999811

RECRUITING 30 participants

Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy

Endeavor Health

NCT06314009

RECRUITING NA 30 participants

Preliminary Effectiveness of Enhanced Text Message + Incentives

University of Kansas Medical Center

NCT07420621

RECRUITING 25 participants

Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants

Amivas

NCT05285735

RECRUITING 20 participants

Bempedoic Acid Pregnancy Surveillance Program

Esperion Therapeutics

NCT05103254

RECRUITING NA 15 participants

Peroneal Electrical Nerve Stimulation in Pregnancy for Restless Legs Syndrome

Rhode Island Hospital

NCT07144631

RECRUITING NA 15 participants

Maternal Fetal Device Performance Twins

GE Healthcare

NCT06835647

RECRUITING 10 participants

Maternal and Postnatal Outcomes Study (MOS): A Global Observational Registry Assessing the Safety of Elfabrio® in Women With Fabry Disease and Their Infants During Pregnancy and Breastfeeding

Chiesi Farmaceutici S.p.A.

NCT06941025

ACTIVE NOT RECRUITING NA 4,633 participants

Michigan Contraceptive Access, Research, and Evaluation Study: Phase 1

University of Michigan

NCT03673007

ACTIVE NOT RECRUITING NA 4,232 participants

Mother and Infant Home Visiting Program Evaluation

MDRC

NCT02069782

ACTIVE NOT RECRUITING 2,050 participants

Maternal Obesity, Breast Milk Composition, and Infant Growth

University of Minnesota

NCT03301753

ACTIVE NOT RECRUITING 861 participants

A Study to Assess the Pregnancy Outcome in Women Exposed to Dayvigo® During Pregnancy Compared to an Unexposed Control Population

Eisai

NCT06744673

ACTIVE NOT RECRUITING NA 450 participants

upREACH Perinatal Home Visitation Program

Baylor College of Medicine

NCT06133829

ACTIVE NOT RECRUITING 450 participants

Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy

The Miriam Hospital

NCT02917876

ACTIVE NOT RECRUITING NA 284 participants

The Expecting Study

Arkansas Children's Hospital Research Institute

NCT02125149

ACTIVE NOT RECRUITING NA 276 participants

Prenatal Starting Early Program mHealth

NYU Langone Health

NCT06087133

ACTIVE NOT RECRUITING NA 262 participants

Positive Airway Pressure, Sleep Apnea, and the Placenta (PAP-SAP)

The Miriam Hospital

NCT02412696

ACTIVE NOT RECRUITING NA 250 participants

Calcium Carbonate on Labor Induction

Wake Forest University Health Sciences

NCT06352775

ACTIVE NOT RECRUITING NA 194 participants

Modulating Early Life Microbiome Through Dietary Intervention in Crohn's Disease

Icahn School of Medicine at Mount Sinai

NCT03850600

ACTIVE NOT RECRUITING NA 168 participants

Improving Maternal and Child Health Through Prenatal Fatty Acid Supplementation

University of Chicago

NCT02647723

ACTIVE NOT RECRUITING 150 participants

Maternal Stress and Blood Sugar Metabolization

Sanford Health

NCT05798377

ACTIVE NOT RECRUITING NA 117 participants

Group Versus Traditional Prenatal Care for Diabetes

Washington University School of Medicine

NCT03301792

ACTIVE NOT RECRUITING 100 participants

A Study to Assess Maternal and Fetal Outcomes After Taking Prucalopride During Pregnancy

Takeda

NCT04961840

ACTIVE NOT RECRUITING NA 70 participants

A Multimedia Presentation to Augment the Informed Consent Process for Anesthesia for Patients Undergoing Scheduled Caesarian Delivery

Northwestern University

NCT06945250

ACTIVE NOT RECRUITING NA 50 participants

Development of a Lifestyle Physical Activity Intervention to Reduce Risk for Perinatal Cannabis Use - RCT

Butler Hospital

NCT06239701

ACTIVE NOT RECRUITING NA 40 participants

Effects of Increased Maternal Choline Intake on Child Cognitive Development

Cornell University

NCT04987099

ACTIVE NOT RECRUITING NA 20 participants

Enhancing Mental and Physical Health of Women Veterans

VA Office of Research and Development

NCT05050266

ACTIVE NOT RECRUITING NA 17 participants

Hearty Meals for Mom- Pilot Study of Meal Delivery for Cardiometabolic Health During Pregnancy

University of Alabama at Birmingham

NCT05512247

COMPLETED 30,570 participants

Establishment of a Perinatal Database and a Bank of Biological Materials

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT00339235

COMPLETED NA 11,108 participants

Fetal ST Segment and T Wave Analysis in Labor

The George Washington University Biostatistics Center

NCT01131260

COMPLETED 10,038 participants

Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01322529

Phase Distribution

PhaseTrial count
Early Phase 1 8
Phase 2 4
Phase 3 9
Phase 4 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pregnancy Trial Landscape

ClinicalTrials.gov lists 194 US studies indexed under Pregnancy, and 77 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Pregnancy shows 11 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Pregnancy is led by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) with 8 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 100 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pregnancy?

PlainTrial tracks 194 US clinical trials for Pregnancy, of which 77 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pregnancy?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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