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NCT05462704 · ClinicalTrials.gov registry record · Phase 3

Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy

A Phase 3 study of Pregnancy and Iron Deficiency Anemia, sponsored by Women and Infants Hospital of Rhode Island.

Recruiting
Registry status
Phase 3
Development phase
300
Enrollment target
8
Study locations

NCT05462704 is a Phase 3 study of Pregnancy and Iron Deficiency Anemia that is actively recruiting participants, run by Women and Infants Hospital of Rhode Island. The registered enrollment target is 300 participants, below the 871-participant average among 191 other Pregnancy trials with a reported enrollment target (66% lower). The trial reports 8 study locations across 7 states.

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The verdict

NCT05462704, a Phase 3 study of Pregnancy and Iron Deficiency Anemia, is actively recruiting participants, sponsored by Women and Infants Hospital of Rhode Island.

RECRUITING
Registry status
Phase 3
Development phase
300 participants
Enrollment target
8
Study locations

Study Summary

Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=300) to test the central hypothesis that IV iron in pregnant women with IDA (Hb\<11 g/dL and ferritin\<30 ng/mL) at 13 - 30 weeks will be effective, safe and cost-effective in reducing severe maternal morbidity-as measured by maternal anemia at delivery-and will also improve offspring neurodevelopment.

Interventions

  • DRUG Ferric derisomaltose
  • DRUG Ferrous sulfate

Study Locations (8)

Rhode Island

  • Hasbro Children's Hospital - Providence
  • Women & Infants Hospital of Rhode Island - Providence

Alabama

  • University of Alabama Medical Center - Birmingham

Florida

  • GNP Research at Heme-on-Call - Miami

Michigan

  • Michigan University Medical Center - Ann Arbor

Missouri

  • Washington University Medical Center - St Louis

Oregon

  • Oregon Health and Sciences Uiversity Medical Center - Portland

Utah

  • University of Utah Hospital - Salt Lake City

Trial Details

FieldValue
Enrollment Target 300 participants
Start Date 2023-01-17
Est. Completion 2027-03-31
Phase Phase 3

What the Registry Record Tells You About NCT05462704

The ClinicalTrials.gov registry entry for NCT05462704 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 871-participant average among 191 other Pregnancy trials with a reported enrollment target (66% lower). The listed sponsor is Women and Infants Hospital of Rhode Island, which has 65 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Pregnancy appearing as the primary indexed condition, and to 2 interventions - of which Ferric derisomaltose is the first listed.

NCT05462704 reports 8 study locations spanning 7 distinct geographic areas - top geographies include Rhode Island, Alabama, Florida.

Frequently Asked Questions

What is clinical trial NCT05462704 about?

NCT05462704 is a clinical study titled "Intravenous Versus Oral Iron for Treating Iron-Deficiency Anemia in Pregnancy". Double blind, placebo controlled, multicenter randomized trial in pregnant women in the U.S. (N=300) to test the central hypothesis that IV iron in pregnant women with IDA (Hb\<11 g/dL and ferritin\<30 ng/mL) at 13 - 30 weeks will be effective, safe and cost-effective in reducing severe maternal mor...

What is the current status of trial NCT05462704?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 300 participants. The study started on 2023-01-17. Estimated completion is 2027-03-31.

What conditions does trial NCT05462704 study?

This clinical trial studies the following conditions: Pregnancy, Iron Deficiency Anemia.

What interventions are being tested in trial NCT05462704?

The interventions under investigation include: Ferric derisomaltose (DRUG), Ferrous sulfate (DRUG).

Who is sponsoring clinical trial NCT05462704?

This trial is sponsored by Women and Infants Hospital of Rhode Island, which has 65 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05462704 being conducted?

This trial has 8 study locations across Alabama, Florida, Michigan, Missouri, Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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