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NCT07207876 · ClinicalTrials.gov registry record

Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy

A clinical trial of Pregnancy, sponsored by International Maternal Pediatric Adolescent AIDS Clinical Trials Group.

Recruiting
Registry status
110
Enrollment target
9
Study locations

NCT07207876: Recruiting study of Pregnancy, sponsored by International Maternal Pediatric Adolescent AIDS Clinical Trials Group.

NCT07207876 is a study of Pregnancy that is actively recruiting participants, run by International Maternal Pediatric Adolescent AIDS Clinical Trials Group. The registered enrollment target is 110 participants, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (87% lower). The trial reports 9 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07207876, a study of Pregnancy, is actively recruiting participants, sponsored by International Maternal Pediatric Adolescent AIDS Clinical Trials Group.

RECRUITING
Registry status
110 participants
Enrollment target
9
Study locations

Study Summary

IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study clinical care providers will be enrolled at study sites located in the United States. Approximately 22 infants of pregnant participants receiving benzathine penicillin G will also be enrolled.

Primary Outcome

Arm 1A

Conditions Studied

Interventions

  • DRUG Ceftriaxon
  • DRUG Benzathine penicillin G

Study Locations (9)

New York

  • Site 5040, SUNY Stony Brook NICHD CRS - Stony Brook
  • Site 5114, Bronx-Lebanon Hospital Center NICHD CRS - The Bronx
  • Site 5013, Jacobi Med. Ctr. Bronx NICHD CRS - The Bronx

California

  • Site 5048, USC - Maternal Child Adolescent/Adult Center - Los Angeles
  • Site 5112, David Geffen School of Medicine at UCLA NICHD CRS - Los Angeles

Illinois

  • Site 5083, Rush Univ. Cook County Hosp. Chicago NICHD CRS - Chicago
  • Site 4001, Lurie Children's Hospital of Chicago (LCH) CRS - Chicago

Texas

  • Site 5128, Baylor College of Medicine/Texas Children's Hospital NICHD CRS - Houston

Other

  • Site 5129, IMPAACT/Gamma Project/UPR Pediatric HIV/AIDS Research CRS - San Juan

Trial Details

FieldValue
Enrollment Target 110 participants
Start Date 2026-02-16
Est. Completion 2027-04-30

What NCT07207876 shows while recruiting

NCT07207876 is an observational study that tracks outcomes without assigning an intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, below the 872-participant average among 191 other Pregnancy trials with a reported enrollment target (87% lower).

The record links to 1 condition, with Pregnancy appearing as the primary indexed condition, and to 2 interventions - of which Ceftriaxon is the first listed.

NCT07207876 lists 9 locations in 5 states (New York, California, Illinois).

Frequently Asked Questions

What is clinical trial NCT07207876 about?

NCT07207876 is a clinical study titled "Study of Ceftriaxone and Benzathine Penicillin G During Pregnancy". IMPAACT 2044 is a study to characterize the pharmacokinetics (PK) and safety of ceftriaxone and benzathine penicillin G during pregnancy. Up to 78 pregnant women receiving (1) ceftriaxone for indications other than syphilis or (2) benzathine penicillin G for treatment of syphilis from non-study clin...

What is the current status of trial NCT07207876?

This trial is currently recruiting. The enrollment target is 110 participants. The study started on 2026-02-16. Estimated completion is 2027-04-30.

What conditions does trial NCT07207876 study?

This clinical trial studies the following conditions: Pregnancy.

What interventions are being tested in trial NCT07207876?

The interventions under investigation include: Ceftriaxon (DRUG), Benzathine penicillin G (DRUG).

Who is sponsoring clinical trial NCT07207876?

This trial is sponsored by International Maternal Pediatric Adolescent AIDS Clinical Trials Group, which has 17 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07207876 being conducted?

This trial has 9 study locations across California, Illinois, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pregnancy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07207876's enrollment target sits among peer trials

110 114th of 191 higher than 78 of 191 other Pregnancy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pregnancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07207876, the US trial registry maintained by the National Library of Medicine. NCT07207876 (mid enrollment · multi site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.