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NCT05656378 · ClinicalTrials.gov registry record
A Repository to Study Host-Microbiome Interactions in Health and Disease
A clinical trial of Pregnancy and Healthy (Controls), sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Recruiting
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT05656378: Recruiting study of Pregnancy and Healthy (Controls), sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT05656378 is a study of Pregnancy and Healthy (Controls) that is actively recruiting participants, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 600 participants, below the 870-participant average among 191 other Pregnancy trials with a reported enrollment target (31% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05656378, a study of Pregnancy and Healthy (Controls), is actively recruiting participants, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, they need samples of the microbiome living on the bodies of many people. The purpose of this natural history study is to collect microbiome samples in a repository. These samples will be used for future research. Objective: To collect microbiome samples from the body that can be used for future research. Eligibility: People of any age. Only those older than 3 years will be seen at the NIH clinic. Design: Participants will fill out a questionnaire. Topics will include their medical history and foods they eat. Participants will be asked to give 1 or more of the following: Stool, urine, saliva, vaginal fluid, and breastmilk. These samples can be collected at home and sent to the researchers. Cells from participants cheek, nose, mouth, skin, rectum, and/or vagina. The cells may be collected by rubbing the area with a sterile cotton swab. These procedures can also be done at home. Blood. Blood may be drawn using a needle inserted into a vein in the arm. For young children, blood may be collected by a prick on the heel or finger. Intestinal tissue samples. These may be collected from participants who are having an endoscopy or colonoscopy for other reasons. Skin tissue samples. These may be collected from participants who are having biopsies for other reasons.
Primary Outcome
To provide samples for use in secondary research for evaluation of assay validation, optimization of techniques for collection, storage, processing and analyzing samples, control samples for research tests in other studies, and identification of potential targets from which clinical trials can be designed to better understand or mitigate microbiome associated diseases
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2023-03-09 |
| Est. Completion | 2032-01-01 |
What NCT05656378 shows while recruiting
NCT05656378 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 870-participant average among 191 other Pregnancy trials with a reported enrollment target (31% lower).
The record links to 4 conditions, with Pregnancy appearing as the primary indexed condition, and to 0 interventions.
NCT05656378 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05656378 about?
NCT05656378 is a clinical study titled "A Repository to Study Host-Microbiome Interactions in Health and Disease". Background: The microbiome is the bacteria and other microorganisms that live inside and on the body. The microbiome is important for our health. Researchers study how the microbiome help people stay healthy. They study how the microbiome affects the body when people get sick. To do this research, ...
What is the current status of trial NCT05656378?
This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2023-03-09. Estimated completion is 2032-01-01.
What conditions does trial NCT05656378 study?
This clinical trial studies the following conditions: Pregnancy, Healthy (Controls), Pediatric Illnesses, Inflammatory Diseases.
Who is sponsoring clinical trial NCT05656378?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05656378 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pregnancy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05656378's enrollment target sits among peer trials
600 37th of 191 higher than 153 of 191 other Pregnancy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pregnancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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