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Posttraumatic Stress Disorder (PTSD): early-phase trial registry
21 of 32 indexed Posttraumatic Stress Disorder (PTSD) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #477 of 28,707 conditions by registered trial count.
32 US clinical trials · 21 currently recruiting · #477 of 28,707 conditions by registered trial count
Posttraumatic Stress Disorder (PTSD): 32 US clinical trials tracked, 21 recruiting.
Posttraumatic Stress Disorder (PTSD) is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 21 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 7 of these trials.
Enrollment posture brief
Registry condition posttraumatic-stress-disorder-ptsd
OPEN 21 | RECR 66% | LATE 2 | EARLY 9 | RANK #477 | SPON 7
Volume-matched condition peers
Nearest open-share peer: Hematopoietic and Lymphoid System Neoplasm (66% recruiting · 32 trials)
Posttraumatic Stress Disorder (PTSD) lists 21 open slots (66% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Posttraumatic Stress Disorder (PTSD) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Posttraumatic Stress Disorder (PTSD) is recruiting above its size-band peers.
21 of 32 indexed trials (65.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Posttraumatic Stress Disorder (PTSD) research.
VA Office of Research and Development accounts for 7 of 32 trials (21.9%). 20 distinct sponsors appear on at least one study for this condition label.
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Typical Posttraumatic Stress Disorder (PTSD) enrolment sits around 94 participants.
Median target enrolment is 94 among the 32 trials that report a genuine target (sentinel values excluded). 18 of those (56.3%) plan for fewer than 100 participants.
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Posttraumatic Stress Disorder (PTSD) research is mostly interventional.
32 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
32 total, page 1 of 1
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
VA Office of Research and Development
NCT06162741
Inflammatory Challenge and Fear
University of California, San Francisco
NCT06630884
Examining Intranasal Oxytocin Augmentation of Brief Couples Therapy for Veterans With PTSD
VA Office of Research and Development
NCT06194851
Mindful Self-Compassion to Address PTSD and Substance Use in Unhoused Women
University of California, Los Angeles
NCT06646692
Shared Decision Making in PTSD Treatment
The University of Texas Health Science Center at San Antonio
NCT06953687
Augmenting Massed Cognitive Processing Therapy (CPT) to Prevent Suicide Risk Among Patients With PTSD
Ohio State University
NCT07238192
Project COMET: Massed Prolonged Exposure for PTSD and SUD
Rutgers, The State University of New Jersey
NCT06968832
Treatment for PTSD and Tinnitus
The University of Texas Health Science Center at San Antonio
NCT07106593
A Neurosensory Account of Anxiety and Stress (Study 2)
The University of Texas Health Science Center, Houston
NCT07079839
A Neurosensory Account of Anxiety and Stress (Study 1)
The University of Texas Health Science Center, Houston
NCT05895006
Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD
The University of Texas Health Science Center, Houston
NCT07116109
Evaluating Treatments for Suicidal Veterans With PTSD
VA Office of Research and Development
NCT05974631
NightWare and Cardiovascular Health in Veterans With PTSD
VA Office of Research and Development
NCT06419959
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Texas Tech University Health Sciences Center
NCT06903819
Integrated Treatment for Opioid Use Disorder and PTSD
Medical University of South Carolina
NCT06641115
Suvorexant for Treatment of AUD and PTSD
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06679062
Methylphenidate for the Treatment of PTSD With Associated Neurocognitive Complaints
VA Office of Research and Development
NCT05776056
Cognitive Processing Therapy (CPT) for Perinatal Posttraumatic Stress Disorder (PTSD)
University of Texas at Austin
NCT07060144
Targeted Accelerated TMS for Post-Traumatic Stress Disorder
Brigham and Women's Hospital
NCT07245641
Open Pilot Trial of Adapted Cognitive Processing Therapy for Comorbid PTSD and Opioid Use Disorder
The City College of New York
NCT06872164
Effect of Sublingual Formulation of Dexmedetomidine Hydrochloride (HCl) (BXCL501) - Outpatient Study
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
NCT06335407
The Impact of Vocational Rehabilitation on Mentally III Veterans
VA Office of Research and Development
NCT00333801
fMRI Predictors of Treatment Response in Posttraumatic Stress Disorder (PTSD)
Research Foundation for Mental Hygiene
NCT01576510
Brain Imaging of Psychotherapy for Posttraumatic Stress Disorder (PTSD)
Stanford University
NCT01507948
Occupational Therapy Driving Intervention for Returning Combat Veterans.
University of Florida
NCT02764983
Effectiveness of a Driving Intervention on Safe Community Mobility for Returning Combat Veterans
University of Florida
NCT02765672
Acupuncture for the Treatment of Posttraumatic Stress Among Military Personnel
Henry M. Jackson Foundation for the Advancement of Military Medicine
NCT00320138
Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders
Seattle Institute for Biomedical and Clinical Research
NCT02322047
Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence
Yale University
NCT01847469
Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
VA Office of Research and Development
NCT03283163
Oxytocin and Affect Processing in Posttraumatic Stress Disorder
Yale University
NCT02546570
A Clinical Trial for Post Traumatic Stress Disorder
Antonia New
NCT00554177
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 5 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Posttraumatic Stress Disorder (PTSD) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Posttraumatic Stress Disorder (PTSD) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Posttraumatic Stress Disorder (PTSD) page
32 registered trials, 21 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 21 Posttraumatic Stress Disorder (PTSD) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Posttraumatic Stress Disorder (PTSD) trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Posttraumatic Stress Disorder (PTSD) condition card totals 32 registered trials; most-linked intervention Cognitive Processing Therapy; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.