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NCT06968832 · ClinicalTrials.gov registry record · NA
Project COMET: Massed Prolonged Exposure for PTSD and SUD
A NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders, sponsored by Rutgers, The State University of New Jersey.
- Recruiting
- Registry status
- NA
- Development phase
- 168
- Enrollment target
- 1
- Study location
NCT06968832: Recruiting NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders, sponsored by Rutgers, The State University of New Jersey.
NCT06968832 is a NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 168 participants, above the 106-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (58% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06968832, a NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.
- RECRUITING
- Registry status
- NA
- Development phase
- 168 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for substance use disorder (SUD). The main questions it aims to answer are: * Does M-PE reduce PTSD symptoms more effectively than trauma treatment as usual (TAU)? * Does M-PE reduce the number of days participants use substances? * How do patient-centered outcomes (such as depression, suicidal thoughts, and quality of life) differ between M-PE and trauma TAU? * Researchers will compare M-PE to treatment as usual to see if M-PE leads to better mental health and substance use outcomes and lower dropout rates. Participants will: * Attend multiple therapy sessions per week (M-PE) or receive usual care * Complete assessments at baseline, during treatment, end-of-treatment, 1-month, 3-month, and 6-month follow-up * Share feedback through surveys and interviews about their experience in the program
Primary Outcome
Measures PTSD symptom severity, score range 0-80, higher scores mean greater symptom severity
Conditions Studied
Interventions
- BEHAVIORAL Massed Prolonged Exposure Therapy (M-PE)
- BEHAVIORAL Standard outpatient SUD care
Study Locations (1)
Florida
- Gateway Community Services - Jacksonville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 168 participants |
| Start Date | 2025-09-02 |
| Est. Completion | 2029-06-30 |
| Phase | NA |
What NCT06968832 shows while recruiting
NCT06968832 is an interventional study that assigns participants to a tested intervention. The registered 168 participants enrollment target is mid-sized for trials with a published cap, above the 106-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (58% higher).
The record links to 4 conditions, with Posttraumatic Stress Disorder (PTSD) appearing as the primary indexed condition, and to 2 interventions - of which Massed Prolonged Exposure Therapy (M-PE) is the first listed.
NCT06968832 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT06968832 about?
NCT06968832 is a clinical study titled "Project COMET: Massed Prolonged Exposure for PTSD and SUD". The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for substance use disorder (SUD). The main questions it aims to answer are: * Does M-PE reduce PTSD sym...
What is the current status of trial NCT06968832?
This trial is currently recruiting. It is a NA study. The enrollment target is 168 participants. The study started on 2025-09-02. Estimated completion is 2029-06-30.
What conditions does trial NCT06968832 study?
This clinical trial studies the following conditions: Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders, Substance Use Disorders (SUD), Comorbidity.
What interventions are being tested in trial NCT06968832?
The interventions under investigation include: Massed Prolonged Exposure Therapy (M-PE) (BEHAVIORAL), Standard outpatient SUD care (BEHAVIORAL).
Who is sponsoring clinical trial NCT06968832?
This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06968832 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Posttraumatic Stress Disorder (PTSD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06968832's enrollment target sits among peer trials
168 7th of 31 higher than 25 of 31 other Posttraumatic Stress Disorder (PTSD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Posttraumatic Stress Disorder (PTSD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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