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NCT06968832 · ClinicalTrials.gov registry record · NA

Project COMET: Massed Prolonged Exposure for PTSD and SUD

A NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders, sponsored by Rutgers, The State University of New Jersey.

Recruiting
Registry status
NA
Development phase
168
Enrollment target
1
Study location

NCT06968832 is a NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders that is actively recruiting participants, run by Rutgers, The State University of New Jersey. The registered enrollment target is 168 participants, above the 105-participant average among 17 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (60% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT06968832, a NA study of Posttraumatic Stress Disorder (PTSD) and Trauma and Stressor Related Disorders, is actively recruiting participants, sponsored by Rutgers, The State University of New Jersey.

RECRUITING
Registry status
NA
Development phase
168 participants
Enrollment target
1
Study location

Study Summary

The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for substance use disorder (SUD). The main questions it aims to answer are: * Does M-PE reduce PTSD symptoms more effectively than trauma treatment as usual (TAU)? * Does M-PE reduce the number of days participants use substances? * How do patient-centered outcomes (such as depression, suicidal thoughts, and quality of life) differ between M-PE and trauma TAU? * Researchers will compare M-PE to treatment as usual to see if M-PE leads to better mental health and substance use outcomes and lower dropout rates. Participants will: * Attend multiple therapy sessions per week (M-PE) or receive usual care * Complete assessments at baseline, during treatment, end-of-treatment, 1-month, 3-month, and 6-month follow-up * Share feedback through surveys and interviews about their experience in the program

Conditions Studied

Posttraumatic Stress Disorder (PTSD) Trauma and Stressor Related Disorders Substance Use Disorders (SUD) Comorbidity

Interventions

  • BEHAVIORAL Massed Prolonged Exposure Therapy (M-PE)
  • BEHAVIORAL Standard outpatient SUD care

Study Locations (1)

Florida

  • Gateway Community Services - Jacksonville

Trial Details

FieldValue
Enrollment Target 168 participants
Start Date 2025-09-02
Est. Completion 2029-06-30
Phase NA

Sponsor

Rutgers, The State University of New Jersey

413 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06968832

The ClinicalTrials.gov registry entry for NCT06968832 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 168 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 105-participant average among 17 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (60% higher). The listed sponsor is Rutgers, The State University of New Jersey, which has 413 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Posttraumatic Stress Disorder (PTSD) appearing as the primary indexed condition, and to 2 interventions - of which Massed Prolonged Exposure Therapy (M-PE) is the first listed.

NCT06968832 reports 1 study location spanning 1 distinct geographic area - top geographies include Florida.

Frequently Asked Questions

What is clinical trial NCT06968832 about?

NCT06968832 is a clinical study titled "Project COMET: Massed Prolonged Exposure for PTSD and SUD". The goal of this clinical trial is to learn if Massed Prolonged Exposure Therapy (M-PE) can improve PTSD symptoms and reduce substance use in adults receiving intensive outpatient (IOP) treatment for substance use disorder (SUD). The main questions it aims to answer are: * Does M-PE reduce PTSD sym...

What is the current status of trial NCT06968832?

This trial is currently recruiting. It is a NA study. The enrollment target is 168 participants. The study started on 2025-09-02. Estimated completion is 2029-06-30.

What conditions does trial NCT06968832 study?

This clinical trial studies the following conditions: Posttraumatic Stress Disorder (PTSD), Trauma and Stressor Related Disorders, Substance Use Disorders (SUD), Comorbidity.

What interventions are being tested in trial NCT06968832?

The interventions under investigation include: Massed Prolonged Exposure Therapy (M-PE) (BEHAVIORAL), Standard outpatient SUD care (BEHAVIORAL).

Who is sponsoring clinical trial NCT06968832?

This trial is sponsored by Rutgers, The State University of New Jersey, which has 413 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06968832 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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