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NCT07116109 · ClinicalTrials.gov registry record · NA
Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD
A NA study of Chronic Pain and Posttraumatic Stress Disorder (PTSD), sponsored by The University of Texas Health Science Center, Houston.
- Recruiting
- Registry status
- NA
- Development phase
- 146
- Enrollment target
- 1
- Study location
NCT07116109: Recruiting NA study of Chronic Pain and Posttraumatic Stress Disorder (PTSD), sponsored by The University of Texas Health Science Center, Houston.
NCT07116109 is a NA study of Chronic Pain and Posttraumatic Stress Disorder (PTSD) that is actively recruiting participants, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 146 participants, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07116109, a NA study of Chronic Pain and Posttraumatic Stress Disorder (PTSD), is actively recruiting participants, sponsored by The University of Texas Health Science Center, Houston.
- RECRUITING
- Registry status
- NA
- Development phase
- 146 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to examine comparative effectiveness of two home-based telemedicine delivered interventions: transcranial Direct Current Stimulation (tDCS) combined with Massed Prolonged Exposure (Massed-PE) vs. Sham tDCS combined with Massed PE, focusing on pain and PTSD outcomes, to determine the comparative effectiveness of the two interventions on process outcomes of patient satisfaction, treatment attrition, and treatment compliance and to explore changes in blood biomarkers associated with stress and inflammatory processes related to pain and PTSD symptom improvements following treatment.
Primary Outcome
The DVPRS is a validated 11-point numeric rating scale and is scored from 0(no pain at all) to 10(worst pain ever possible), higher scores indicate greater pain severity.
Conditions Studied
Interventions
- DEVICE Transcranial Direct Current Stimulation (tDCS)
- BEHAVIORAL Massed-Prolonged Exposure (PE)
- DEVICE Sham Transcranial Direct Current Stimulation (tDCS)
Study Locations (1)
Texas
- The University of Texas Health Science Center at Houston - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 146 participants |
| Start Date | 2025-07-01 |
| Est. Completion | 2029-06-30 |
| Phase | NA |
What NCT07116109 shows while recruiting
NCT07116109 is an interventional study that assigns participants to a tested intervention. The registered 146 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 301 other Chronic Pain trials with a reported enrollment target (81% lower).
The record links to 2 conditions, with Chronic Pain appearing as the primary indexed condition, and to 3 interventions - of which Transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT07116109 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07116109 about?
NCT07116109 is a clinical study titled "Neuromodulation + Prolonged Exposure Therapy: Evaluation of a Technology-Enhanced, Integrated Treatment for Pain and PTSD". The purpose of this study is to examine comparative effectiveness of two home-based telemedicine delivered interventions: transcranial Direct Current Stimulation (tDCS) combined with Massed Prolonged Exposure (Massed-PE) vs. Sham tDCS combined with Massed PE, focusing on pain and PTSD outcomes, to d...
What is the current status of trial NCT07116109?
This trial is currently recruiting. It is a NA study. The enrollment target is 146 participants. The study started on 2025-07-01. Estimated completion is 2029-06-30.
What conditions does trial NCT07116109 study?
This clinical trial studies the following conditions: Chronic Pain, Posttraumatic Stress Disorder (PTSD).
What interventions are being tested in trial NCT07116109?
The interventions under investigation include: Transcranial Direct Current Stimulation (tDCS) (DEVICE), Massed-Prolonged Exposure (PE) (BEHAVIORAL), Sham Transcranial Direct Current Stimulation (tDCS) (DEVICE).
Who is sponsoring clinical trial NCT07116109?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07116109 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Chronic Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07116109's enrollment target sits among peer trials
146 108th of 301 higher than 194 of 301 other Chronic Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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