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NCT03283163 · ClinicalTrials.gov registry record · NA
Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD
A NA study of Posttraumatic Stress Disorder (PTSD) and Chronic Musculoskeletal Pain, sponsored by VA Office of Research and Development.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT03283163: Completed NA study of Posttraumatic Stress Disorder (PTSD) and Chronic Musculoskeletal Pain, sponsored by VA Office of Research and Development.
NCT03283163 is a NA study of Posttraumatic Stress Disorder (PTSD) and Chronic Musculoskeletal Pain that has completed, run by VA Office of Research and Development. The registered enrollment target is 23 participants, below the 111-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03283163, a NA study of Posttraumatic Stress Disorder (PTSD) and Chronic Musculoskeletal Pain, has completed, sponsored by VA Office of Research and Development.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
The wars in Iraq and Afghanistan are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions from recent deployment-related physical injuries and exposure to psychological trauma. Health behavior change has become increasingly important in treating these conditions and proactively preventing long-term negative health sequelae, in order to benefit these Veterans directly and reduce the growing challenges to the healthcare system. The proposed CDA-2 program of research will use an innovative translational research approach to study whether a chronic progressive -based exercise program will reduce chronic pain symptoms in patients with varying degrees of PTSD symptom severity and to elucidate and modify potential PTSD-related deficiencies in neurobiological and psychological responses to exercise to optimize the physical and psychological benefits of exercise for these individuals.
Primary Outcome
To be administered at: Endpoint Exercise Test Evaluation Session (week 13). The PCL is a 20-item self-report that assesses the extent to which an individual is bothered by each PTSD symptom during the past month using a 5-point Likert-type scale. The PCL-5 is undergoing validation, but the previous PCL based on DSM-IV had good sensitivity (.82) and specificity (.83). Scoring for each item is on a 0-4 scale with higher scores indicating higher symptom severity. A total symptom severity score (ran
Conditions Studied
Interventions
- BEHAVIORAL Exercise Testing and Training
Study Locations (1)
Massachusetts
- VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2014-08-25 |
| Est. Completion | 2022-08-31 |
| Phase | NA |
What the finished NCT03283163 record still lists
NCT03283163 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 111-participant average among 31 other Posttraumatic Stress Disorder (PTSD) trials with a reported enrollment target (79% lower).
The record links to 3 conditions, with Posttraumatic Stress Disorder (PTSD) appearing as the primary indexed condition, and to 1 intervention - of which Exercise Testing and Training is the first listed.
NCT03283163 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT03283163 about?
NCT03283163 is a clinical study titled "Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD". The wars in Iraq and Afghanistan are creating a new generation of Veterans, including an increasing number of women Veterans, who present with comorbid PTSD and chronic pain conditions from recent deployment-related physical injuries and exposure to psychological trauma. Health behavior change has b...
What is the current status of trial NCT03283163?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2014-08-25. Estimated completion is 2022-08-31.
What conditions does trial NCT03283163 study?
This clinical trial studies the following conditions: Posttraumatic Stress Disorder (PTSD), Chronic Musculoskeletal Pain, Mild or Moderate Traumatic Brain Injury.
What interventions are being tested in trial NCT03283163?
The interventions under investigation include: Exercise Testing and Training (BEHAVIORAL).
Who is sponsoring clinical trial NCT03283163?
This trial is sponsored by VA Office of Research and Development, which has 1,668 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03283163 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03283163's enrollment target sits among peer trials
23 28th of 31 higher than 4 of 31 other Posttraumatic Stress Disorder (PTSD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Posttraumatic Stress Disorder (PTSD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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