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NCT06872164 · ClinicalTrials.gov registry record · NA

Open Pilot Trial of Adapted Cognitive Processing Therapy for Comorbid PTSD and Opioid Use Disorder

A NA study of Opioid Use Disorder and Posttraumatic Stress Disorder (PTSD), sponsored by The City College of New York.

Recruiting
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT06872164: Recruiting NA study of Opioid Use Disorder and Posttraumatic Stress Disorder (PTSD), sponsored by The City College of New York.

NCT06872164 is a NA study of Opioid Use Disorder and Posttraumatic Stress Disorder (PTSD) that is actively recruiting participants, run by The City College of New York. The registered enrollment target is 15 participants, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06872164, a NA study of Opioid Use Disorder and Posttraumatic Stress Disorder (PTSD), is actively recruiting participants, sponsored by The City College of New York.

RECRUITING
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

The goal of this open pilot trial is to learn if an adapted version of Cognitive Processing Therapy (CPT), delivered through telehealth, can treat posttraumatic stress disorder (PTSD) in adults who use syringe services programs. The main questions it aims to answer are: * Can the intervention be done in syringe services programs? * Are syringe services program clients and staff open to the intervention? * Can the intervention lower PTSD symptoms and help participants keep taking their medication for opioid use disorder (ex. Buprenorphine or methadone)? Participants will: * Attend 4-18 tele-delivered CPT sessions at the syringe services program * Complete between-session CPT practice with the support of SSP-based "coaches" * Meet with research staff monthly to complete surveys of their PTSD symptoms, drug use, and mental health

Primary Outcome

Proportion of persons eligible to enroll in the study of all possible SSP clients approached during 6-month recruitment period. Assessed using count data of individuals failing screen.

Interventions

  • BEHAVIORAL Cognitive Processing Therapy

Study Locations (1)

New York

  • OnPoint - New York

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2025-11-17
Est. Completion 2026-09
Phase NA
The City College of New York

7 total trials

What NCT06872164 shows while recruiting

NCT06872164 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 4,656-participant average among 257 other Opioid Use Disorder trials with a reported enrollment target (100% lower).

The record links to 2 conditions, with Opioid Use Disorder appearing as the primary indexed condition, and to 1 intervention - of which Cognitive Processing Therapy is the first listed.

NCT06872164 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT06872164 about?

NCT06872164 is a clinical study titled "Open Pilot Trial of Adapted Cognitive Processing Therapy for Comorbid PTSD and Opioid Use Disorder". The goal of this open pilot trial is to learn if an adapted version of Cognitive Processing Therapy (CPT), delivered through telehealth, can treat posttraumatic stress disorder (PTSD) in adults who use syringe services programs. The main questions it aims to answer are: * Can the intervention be do...

What is the current status of trial NCT06872164?

This trial is currently recruiting. It is a NA study. The enrollment target is 15 participants. The study started on 2025-11-17. Estimated completion is 2026-09.

What conditions does trial NCT06872164 study?

This clinical trial studies the following conditions: Opioid Use Disorder, Posttraumatic Stress Disorder (PTSD).

What interventions are being tested in trial NCT06872164?

The interventions under investigation include: Cognitive Processing Therapy (BEHAVIORAL).

Who is sponsoring clinical trial NCT06872164?

This trial is sponsored by The City College of New York, which has 7 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06872164 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Opioid Use Disorder

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06872164's enrollment target sits among peer trials

15 242nd of 257 higher than 11 of 257 other Opioid Use Disorder trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Opioid Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06872164, the US trial registry maintained by the National Library of Medicine. NCT06872164 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.