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ClinicalTrials.gov 12 recruiting now early-phase tilt

Cardiac Arrest: early-phase trial registry

12 of 32 indexed Cardiac Arrest trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #477 of 28,707 conditions by registered trial count.

32 US clinical trials · 12 currently recruiting · #477 of 28,707 conditions by registered trial count

Cardiac Arrest: 32 US clinical trials tracked, 12 recruiting.

Cardiac Arrest is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Children's Hospital of Philadelphia, running 3 of these trials.

Enrollment posture brief

Registry condition cardiac-arrest

OPEN 12 | RECR 38% | LATE 1 | EARLY 9 | RANK #477 | SPON 3

Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)

Hematopoietic and Lymphoid S65.6%Acute Respiratory Distress S43.8%Cardiac Arrest (this)38%Astigmatism28.1%Cardiovascular Risk Factor21.9%
Open-enrollment share among volume-matched conditions near Cardiac Arrest

Cardiac Arrest lists 12 open slots (38% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cardiac Arrest on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cardiac Arrest is recruiting below its size-band peers.

    12 of 32 indexed trials (37.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cardiac Arrest trials is spread across many organizations.

    Children's Hospital of Philadelphia accounts for 3 of 32 trials (9.4%). 27 distinct sponsors appear on at least one study for this condition label.

  3. Typical Cardiac Arrest enrolment sits around 130 participants.

    Median target enrolment is 130 among the 32 trials that report a genuine target (sentinel values excluded). 16 of those (50%) plan for fewer than 100 participants.

  4. Cardiac Arrest splits between interventional and observational designs.

    19 interventional and 13 observational studies make up this index (59.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 22Phase 31

Open and recent trials

32 total, page 1 of 1

RECRUITING 7,000 participants

Quality of Pediatric Resuscitation in a Multicenter Collaborative

Children's Hospital of Philadelphia

NCT02708134

RECRUITING NA 1,060 participants

Hospital Airway Resuscitation Trial

Montefiore Medical Center

NCT05520762

RECRUITING 1,000 participants

Resuscitative TEE Collaborative Registry

University of Pennsylvania

NCT04972526

RECRUITING 600 participants

Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

Boston Medical Center

NCT03261089

RECRUITING Phase 3 585 participants

Early Amiodarone in Shockable Cardiac Arrest

Oregon Health and Science University

NCT06680869

RECRUITING 400 participants

Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)

MaineHealth

NCT02664831

RECRUITING Phase 2 342 participants

Surviving PEA in Roanoke (SPEAR) Study

Carol Bernier

NCT05283850

RECRUITING NA 240 participants

Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study

KidSIM Simulation Program

NCT05868239

RECRUITING Phase 1 178 participants

Post-CA Neuroprotection With Magnesium

NYU Langone Health

NCT06455514

RECRUITING Phase 1 53 participants

Hydrogen's Feasibility and Safety as a Therapy in ECPR

Boston Children's Hospital

NCT05574296

RECRUITING Phase 1 30 participants

Packed Red Blood Cell Transfusion During Cardiac Arrest

NYU Langone Health

NCT06462027

RECRUITING 25 participants

Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest

Byron Drumheller

NCT06511999

ACTIVE NOT RECRUITING NA 30,000 participants

A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning

AgileMD

NCT05893420

ACTIVE NOT RECRUITING 50 participants

fMRI in CardiaC arrEst With Uncertain Prognosis

Brigham and Women's Hospital

NCT06423768

COMPLETED NA 1,001 participants

Code Blue Outcomes & Process Improvement Through Leadership Optimization Using Teleintensivists-Simulation

Intermountain Health Care

NCT03000829

COMPLETED NA 900 participants

SmartCPR Trial: An Analysis of a Waveform-Based Automated External Defibrillation (AED) Algorithm on Survival From Out-of-Hospital Ventricular Fibrillation

New York City Fire Department

NCT00535106

COMPLETED 813 participants

Vfib by ECG or Echo During Cardiac Arrest

Romolo Gaspari

NCT04906252

COMPLETED 793 participants

REASON 1 Trial: Sonography in Cardiac Arrest

University of Massachusetts, Worcester

NCT01446471

COMPLETED 280 participants

Reoxygenation After Cardiac Arrest (REOX Study)

The Cooper Health System

NCT01881243

COMPLETED Phase 1 130 participants

Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation

University of Texas Southwestern Medical Center

NCT00628550

COMPLETED 89 participants

Quantitative Measurement of Cardiopulmonary Resuscitation (CPR) During In Hospital Cardiac Arrest

Children's Hospital of Philadelphia

NCT00628693

COMPLETED 70 participants

A Prospective Analysis of the Effect of Therapeutic Hypothermia After Cardiac Arrest

Advocate Hospital System

NCT00676598

COMPLETED Phase 1 50 participants

Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest

Beth Israel Deaconess Medical Center

NCT00676585

COMPLETED NA 50 participants

A Comparison of CPR Outcomes Between Traditional and Endomorphic Manikins With and Without Equipment

North Dakota State University

NCT04283214

COMPLETED Phase 2 48 participants

Ubiquinol as a Metabolic Resuscitator in Post-Cardiac Arrest

Beth Israel Deaconess Medical Center

NCT02934555

COMPLETED 32 participants

Out-of-hospital Cardiac Arrest (OHCA) Biomarkers

University of Florida

NCT03112486

COMPLETED NA 16 participants

Family-Authored ICU Diaries to Reduce Fear in Patients Experiencing a Cardiac Arrest (FAID Fear)

Columbia University

NCT05144477

COMPLETED Phase 1 16 participants

Reoxygenation After Cardiac Arrest II (REOX II Study)

The Cooper Health System

NCT02698826

COMPLETED NA 14 participants

Open Pilot Trial of a Mind-body Program for Cardiac Arrest Survivors and Their Caregivers

Massachusetts General Hospital

NCT06517394

COMPLETED NA 6 participants

NEURESCUE Device as an Adjunct to In-Hospital Cardiac Arrest (ARISE)

neurescue

NCT05444049

COMPLETED 4 participants

Measurement of the Quality of Pediatric CPR

Children's Hospital of Philadelphia

NCT01265316

COMPLETED Phase 1 2 participants

Washington Study of Hemofiltration After Out-of-Hospital Cardiac Arrest

University of Washington

NCT01509040

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 2
Phase 3 1

Named interventions

Most-linked intervention names on Cardiac Arrest records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Protocol for rapid FiO2 optimization Other
1 trials
FAID Fear Intervention Behavioral
1 trials
There is no intervention for this study. Device
1 trials
Cardiopulmonary Resuscitation Other
1 trials
Simulated "observation" by ICU physician Other
1 trials
Tele-intensivist consultation Other
1 trials
Ubiquinol Drug
1 trials
Recovering Together after Cardiac Arrest Behavioral
1 trials

US sites by state

Facility locations filed on Cardiac Arrest trials. A trial with sites in several states counts in each.

Massachusetts 10 trials
Pennsylvania 8 trials
New York 7 trials
Florida 4 trials
California 4 trials
Missouri 3 trials
Indiana 3 trials
Connecticut 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cardiac Arrest page

32 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cardiac Arrest condition card totals 32 registered trials; most-linked intervention Protocol for rapid FiO2 optimization; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.