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NCT06903819 · ClinicalTrials.gov registry record · Phase 4
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
A Phase 4 study of Depression and Opioid Use, sponsored by Texas Tech University Health Sciences Center.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 90
- Enrollment target
- 2
- Study locations
NCT06903819 is a Phase 4 study of Depression and Opioid Use that is actively recruiting participants, run by Texas Tech University Health Sciences Center. The registered enrollment target is 90 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (89% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT06903819, a Phase 4 study of Depression and Opioid Use, is actively recruiting participants, sponsored by Texas Tech University Health Sciences Center.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 90 participants
- Enrollment target
- 2
- Study locations
Study Summary
The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic stress disorder (PTSD). The main questions it aims to answer are: Does ketamine reduce pain after surgery compared to standard anesthesia? Does ketamine reduce the amount of opioids patients need for pain control? Does ketamine improve symptoms of depression and PTSD after orthopedic trauma? Researchers will compare patients who receive ketamine during surgery with those who receive standard anesthesia without ketamine to see if ketamine helps improve both physical and psychological recovery. Participants will: Be randomly assigned to receive either a single dose of ketamine or standard anesthesia during surgery. Report their pain using a simple pain scale (Visual Analog Scale, VAS). Complete short surveys about mood and mental health (PHQ-9 for depression and PCL-5 for PTSD) at several time points after surgery. Allow the research team to review their electronic medical records to measure opioid prescriptions during recovery. Attend follow-up visits in clinic or by secure telehealth (e.g., Zoom) at 1-7 days, 2-3 weeks, 6 weeks, 3 months, and 6 months after surgery
Conditions Studied
Interventions
- DRUG Ketamine
- DRUG standard general anesthesia
Study Locations (2)
Texas
- Texas Tech University Health Sciences Center Lubbock - Lubbock
- University Medical Center - Lubbock
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2025-11-06 |
| Est. Completion | 2028-05 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06903819
The ClinicalTrials.gov registry entry for NCT06903819 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 786-participant average among 679 other Depression trials with a reported enrollment target (89% lower). The listed sponsor is Texas Tech University Health Sciences Center, which has 76 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Ketamine is the first listed.
NCT06903819 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06903819 about?
NCT06903819 is a clinical study titled "Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients". The goal of this clinical trial is to learn if ketamine, given during surgery, can help improve recovery for adults with serious orthopedic trauma. The study will test whether ketamine reduces pain, lowers the need for opioids, and improves mental health outcomes like depression and post-traumatic s...
What is the current status of trial NCT06903819?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 90 participants. The study started on 2025-11-06. Estimated completion is 2028-05.
What conditions does trial NCT06903819 study?
This clinical trial studies the following conditions: Depression, Opioid Use, Postoperative Pain, Post Traumatic Stress Disorder (PTSD), Orthopedic Trauma Surgery Patients.
What interventions are being tested in trial NCT06903819?
The interventions under investigation include: Ketamine (DRUG), standard general anesthesia (DRUG).
Who is sponsoring clinical trial NCT06903819?
This trial is sponsored by Texas Tech University Health Sciences Center, which has 76 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06903819 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.