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Astigmatism clinical trials
Every US clinical trial registered for Astigmatism — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
32 US clinical trials · 9 currently recruiting
The research picture
Astigmatism has 32 registered US clinical trials, 9 of them open to new participants right now — about 28% of the total.
- 9
- recruiting participants now
- 28%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 5
- top sponsor: Alcon Research
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
Stanford University
NCT02576483
North American Comfilcon A Clinical Study
CooperVision International Limited (CVIL)
NCT06902584
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
Hoopes Vision
NCT07201298
Contoura With Phorcides Compared to Wavefront Optimized LASIK
Daniel Terveen
NCT05486546
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
Stanford University
NCT07078799
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
Center For Sight
NCT07140653
Patient Reported Outcomes With WaveLight Plus LASIK
Mann Eye Institute
NCT07084844
Clinical Evaluation of WaveLight Plus LASIK
Laser Defined Vision
NCT07127757
Comfort and Vision With TOTAL30 Multifocal Lenses
Scripps Poway Eyecare and Optometry
NCT07284966
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
Alcon Research
NCT05796453
LASIK Using Contoura With Phorcides vs. iDesign
59th Medical Wing
NCT07128316
LASIK iDesign vs SMILE
59th Medical Wing
NCT07126756
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
Hoopes Vision
NCT05611294
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
Carl Zeiss Meditec
NCT02430428
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
Alcon Research
NCT01699750
Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
Milton S. Hershey Medical Center
NCT04676451
Conventional Surgery vs. Verion/VerifEye
Carolina Eyecare Physicians
NCT02513745
A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia
Bausch & Lomb Incorporated
NCT00348205
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
Alcon Research
NCT01045733
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
Stanford University
NCT01365728
Patient Satisfaction With Contoura Vision Topography-Guided LASIK
Rush Eye Associates
NCT04903301
Apioc Contact Lens Feasibility
Lentechs
NCT03688672
Corneal Astigmatism Measurement Study
Alcon Research
NCT00818532
Quality of Vision and Quality of Life With LASIK
Edward E. Manche
NCT02161263
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
Johnson & Johnson Vision Care
NCT01120782
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
CooperVision
NCT02921412
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Bausch & Lomb Incorporated
NCT06069609
Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses
Bausch & Lomb Incorporated
NCT05129124
Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial
Innovative Medical
NCT01279031
Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions
Gainesville Eye Associates
NCT02763124
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
Alcon Research
NCT05886907
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
CooperVision
NCT04016623
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Astigmatism Trial Landscape
ClinicalTrials.gov lists 32 US studies indexed under Astigmatism, and 9 of those are currently open to recruitment — roughly 28% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Astigmatism shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 0 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Astigmatism is led by Alcon Research with 5 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 32 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Astigmatism?
PlainTrial tracks 32 US clinical trials for Astigmatism, of which 9 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Astigmatism?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.