Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Astigmatism: later-stage trial registry
9 of 32 indexed Astigmatism trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #477 of 28,707 conditions by registered trial count.
32 US clinical trials · 9 currently recruiting · #477 of 28,707 conditions by registered trial count
Astigmatism: 32 US clinical trials tracked, 9 recruiting.
Astigmatism is the subject of 32 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Alcon Research, running 5 of these trials.
Enrollment posture brief
Registry condition astigmatism
OPEN 9 | RECR 28% | LATE 2 | EARLY 0 | RANK #477 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Pain (28% recruiting · 377 trials)
Astigmatism lists 9 open slots (28% of 32 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Astigmatism on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Astigmatism is recruiting below its size-band peers.
9 of 32 indexed trials (28.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Astigmatism research.
Alcon Research accounts for 5 of 32 trials (15.6%). 21 distinct sponsors appear on at least one study for this condition label.
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Most Astigmatism trials plan to enrol fewer than 100 people.
Median target enrolment is 57 among the 32 trials that report a genuine target (sentinel values excluded). 25 of those (78.1%) plan for fewer than 100 participants.
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Astigmatism research is mostly interventional.
24 interventional and 8 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
32 total, page 1 of 1
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
Stanford University
NCT02576483
North American Comfilcon A Clinical Study
CooperVision International Limited (CVIL)
NCT06902584
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
Hoopes Vision
NCT07201298
Contoura With Phorcides Compared to Wavefront Optimized LASIK
Daniel Terveen
NCT05486546
Wavefront-guided LASIK Surgery Compared to Ray Tracing-Guided LASIK Surgery
Stanford University
NCT07078799
Arcuate Incisions With Light Adjustable Lens for Astigmatism Correction in Lens Surgery
Center For Sight
NCT07140653
Patient Reported Outcomes With WaveLight Plus LASIK
Mann Eye Institute
NCT07084844
Clinical Evaluation of WaveLight Plus LASIK
Laser Defined Vision
NCT07127757
Comfort and Vision With TOTAL30 Multifocal Lenses
Scripps Poway Eyecare and Optometry
NCT07284966
Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix
Alcon Research
NCT05796453
LASIK Using Contoura With Phorcides vs. iDesign
59th Medical Wing
NCT07128316
LASIK iDesign vs SMILE
59th Medical Wing
NCT07126756
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
Hoopes Vision
NCT05611294
Correction of Myopia Wtih or Without Astigmatism Using the VisuMax™ Femtosecond Laser
Carl Zeiss Meditec
NCT02430428
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
Alcon Research
NCT01699750
Femtosecond Laser Assisted Keratotomies for the Management of Corneal Astigmatism
Milton S. Hershey Medical Center
NCT04676451
Conventional Surgery vs. Verion/VerifEye
Carolina Eyecare Physicians
NCT02513745
A Study to Evaluate the Safety and Effectiveness of the Technols 217z Zyoptix System for Hyperopia
Bausch & Lomb Incorporated
NCT00348205
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
Alcon Research
NCT01045733
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
Stanford University
NCT01365728
Patient Satisfaction With Contoura Vision Topography-Guided LASIK
Rush Eye Associates
NCT04903301
Apioc Contact Lens Feasibility
Lentechs
NCT03688672
Corneal Astigmatism Measurement Study
Alcon Research
NCT00818532
Quality of Vision and Quality of Life With LASIK
Edward E. Manche
NCT02161263
Non-dispensing Study to Check Prescription Equivalence of Two Daily Disposable Toric Contact Lens Types
Johnson & Johnson Vision Care
NCT01120782
Performance of Fanfilcon A Toric Lenses After at Least One Month Wearing Enfilcon A Toric Lenses
CooperVision
NCT02921412
Orientation Characteristics of Daily Disposable Toric Contact Lenses
Bausch & Lomb Incorporated
NCT06069609
Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses
Bausch & Lomb Incorporated
NCT05129124
Randomized Comparison of the Abbott WHITESTAR Signature System With Ellips Tranversal Ultrasound vs. the Alcon Infiniti With the Ozil Torsional Handpiece in Phacoemulsification: A Contralaterally-Controlled Trial
Innovative Medical
NCT01279031
Pseudophakic Astigmatic Reduction With Verion-LenSx Arcuate Incisions
Gainesville Eye Associates
NCT02763124
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
Alcon Research
NCT05886907
Clinical Evaluation of Invigor Toric 1-Day Contact Lenses
CooperVision
NCT04016623
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Astigmatism records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Astigmatism trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Astigmatism page
32 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 9 Astigmatism trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Alcon Research sponsors the most Astigmatism trials on record, review their full trial history before evaluating a specific study. See Alcon Research's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Astigmatism condition card totals 32 registered trials; most-linked intervention Commercially available Ultra for Astigmatism Contact Lenses; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.