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Postoperative Pain: later-stage trial registry
42 of 121 indexed Postoperative Pain trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #102 of 28,707 conditions by registered trial count.
121 US clinical trials · 42 currently recruiting · #102 of 28,707 conditions by registered trial count
Postoperative Pain: 121 US clinical trials tracked, 42 recruiting.
Postoperative Pain is the subject of 121 registered US clinical trials on ClinicalTrials.gov, 42 of them currently open to new participants. 55 are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 5 of these trials.
Enrollment posture brief
Registry condition postoperative-pain
OPEN 42 | RECR 35% | LATE 55 | EARLY 23 | RANK #102 | SPON 5
Volume-matched condition peers
Nearest open-share peer: Invasive Breast Carcinoma (35% recruiting · 46 trials)
Postoperative Pain lists 42 open slots (35% of 121 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Postoperative Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Postoperative Pain is recruiting below its size-band peers.
42 of 121 indexed trials (34.7%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Postoperative Pain trials is spread across many organizations.
Medical University of South Carolina accounts for 5 of 121 trials (4.1%). 94 distinct sponsors appear on at least one study for this condition label.
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Typical Postoperative Pain enrolment sits around 100 participants.
Median target enrolment is 100 among the 121 trials that report a genuine target (sentinel values excluded). 59 of those (48.8%) plan for fewer than 100 participants.
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Postoperative Pain research is mostly interventional.
110 interventional and 11 observational studies make up this index (90.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
121 total, page 3 of 3
Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic
Ann & Robert H Lurie Children's Hospital of Chicago
NCT01662401
IV Acetaminophen for Acute Post Operative Pain in C-Section Patients
Montefiore Medical Center
NCT02069184
Postoperative Pain Control in Septum and Sinus Surgery
Corewell Health East
NCT04149964
A Phase 1 Study to Evaluate Pregabalin and Acetaminophen in Healthy Volunteers
Nevakar
NCT04265456
Preoperative Pain Control in Gastric Bypass Surgery Patients
Legacy Health System
NCT01801189
Ultrasound-guided Fascia Iliaca Compartment Block Versus Periarticular Infiltration
University of Texas Southwestern Medical Center
NCT02658240
Optimization of Catheter Insertion Site for Continuous Peripheral Nerve Blocks
University of California, San Diego
NCT00876746
Methadone in Ambulatory Surgery
Washington University School of Medicine
NCT02300077
Pain Control With Total Knee Replacement
Texas Tech University Health Sciences Center
NCT01680549
Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries
John Fowler
NCT02313675
Opioid Education in Total Knee Arthroplasty
Hospital for Special Surgery, New York
NCT05593341
Comparative Study of Two Different Techniques to Perform TAP-blocks
Maimonides Medical Center
NCT02571439
Effectiveness of Cannabidiol vs. Narcotics for Post Operative Pain Control in Elective Shoulder Arthroscopic Surgery
Foundation for Orthopaedic Research and Education
NCT05240755
Genicular Nerve Block for Total Knee Arthroplasty
Duke University
NCT03706313
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Corewell Health East
NCT00672100
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
University of Washington
NCT05338671
Effect of Postoperative Single Dose of Ketamine on Pain After Mastectomy
NYU Langone Health
NCT04831736
Evaluation of the Effectiveness of tDCS in the Management of Perioperative Pain
Medical University of South Carolina
NCT01861587
Intracanalicular Dexamethasone Insert for Post-Corneal Cross-Linking Inflammation and Pain- The LINK Study
Sight Medical Doctors P
NCT04168112
Assess the Feasibility and Efficacy of the CollaRx® Bupivacaine Implant Laparoscopic Inguinal or Umbilical Herniorrhaphy
Innocoll
NCT01224145
Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
Virginia Commonwealth University
NCT06077214
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 8 |
| Phase 2 | 15 |
| Phase 3 | 17 |
| Phase 4 | 38 |
Top Sponsors
Named interventions
Most-linked intervention names on Postoperative Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Postoperative Pain trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Postoperative Pain page
121 registered trials, 42 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 42 Postoperative Pain trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Medical University of South Carolina sponsors the most Postoperative Pain trials on record, review their full trial history before evaluating a specific study. See Medical University of South Carolina's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Postoperative Pain condition card totals 121 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.