Heron Therapeutics

Closed portfolio snapshot

According to ClinicalTrials.gov-derived indexes, Heron Therapeutics sits in the top decile of US sponsors by registered trial count (#668 of 15,742 sponsors by registered trial count).

23 total trials none currently recruiting 22 completed top decile by trial count

Heron Therapeutics: 23 sponsored US clinical trials, none currently recruiting.

Heron Therapeutics sponsors 23 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 22 completed. 10 of these trials are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Postoperative Pain, with 3 trials.

Top-decile sponsor footprint

Heron Therapeutics ranks in the top decile of sponsors by registered trial count (#668 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 79/100

22 of 23 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (95.7%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

23 total, page 1 of 1

COMPLETED Phase 2

HTX-011 in Spinal Surgery

NCT04911062

COMPLETED Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.

NCT06109415

COMPLETED Phase 4

A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE

NCT06109428

TERMINATED Phase 2

Aprepitant Injectable Emulsion in Patients With COVID-19 (GUARDS-1)

NCT04470622

COMPLETED Phase 1

Dose-Escalation Study of HTX-034 Following Bunionectomy

NCT04398329

COMPLETED Phase 2

HTX-011 Administration Study in Planned Caesarean Section Procedure

NCT03955211

COMPLETED Phase 3

Total Knee Arthroplasty (TKA) Study of HTX-011 in an Multimodal Analgesic Regimen (MMA) Regimen

NCT03974932

COMPLETED Phase 3

Study of Post-Herniorrhaphy Non-opioid MMA Regimens

NCT03907176

COMPLETED Phase 2

Phase 2 Bunionectomy HTX-011 Administration Study

NCT03718039

COMPLETED Phase 2

Phase 2 Herniorrhaphy Study for Opioid Elimination

NCT03695367

COMPLETED Phase 4

Bupivacaine HCl PK and Safety in Augmentation Mammoplasty

NCT03705065

COMPLETED Phase 4

Extended Delivery of Bupivacaine Study in Herniorrhaphy

NCT04102267

COMPLETED Phase 3

Bunionectomy Study for Postoperative Analgesia (EPOCH 1)

NCT03295721

COMPLETED Phase 3

Phase 3 Herniorrhaphy Study for Postoperative Analgesia (EPOCH 2)

NCT03237481

COMPLETED Phase 2

Phase 2B Upper Extremity Nerve Block Study

NCT03011333

COMPLETED Phase 2

Total Knee Arthroplasty Infiltration Study for Postoperative Analgesia

NCT03015532

COMPLETED Phase 2

Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

NCT02762929

COMPLETED Phase 2

Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery

NCT02689258

COMPLETED Phase 2

Pilot Herniorrhaphy Study for Postoperative Analgesia

NCT02504580

COMPLETED Phase 2

A Phase 2, Two-Part Evaluation of the Efficacy and Safety of Locally Administered HTX-011 for Postoperative Analgesia Following Bunionectomy

NCT02471898

COMPLETED Phase 3

A Prospective, Multicenter, Study of APF530 (Granisetron) SC for Prevention of CINV in Patients Receiving HEC

NCT02106494

COMPLETED

A Phase I Study of the Effects of APF530 Exposure, Granisetron and Moxifloxacin

NCT01416259

COMPLETED Phase 3

APF530 or Aloxi (Palonosetron Hydrochloride) Combined With Dexamethasone in Preventing Nausea and Vomiting in Patients Receiving Chemotherapy for Cancer

NCT00343460

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 11
Phase 3 6
Phase 4 4

How the Heron Therapeutics archive is shaped

23 indexed studies, none listed as recruiting (0% open); 22 completed (96%).

Phase mix: 10 late (III/IV) vs 12 early (I/II) (balanced across stages).

Top condition: Postoperative Pain (3 trials), 2 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

Heron Therapeutics: archived-pipeline peers nationwide

Peers matched on 23 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

Heron Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0510152025 0%5%10%15%20%25% Total trials Recruiting share Heron TherapeuticsAMAG PharmaceuticalsAtriCureCara TherapeuticsCraig L Slingluff, Jr10xBio22nd Century Group23andMe3-C Institute for Social Development
Heron Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Heron Therapeutics sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 23 archived trials

Sponsors with similar archive density (± trial count)

What to do with this Heron Therapeutics page

23 registered trials is a research-attention snapshot, not an endorsement of Heron Therapeutics or any single study.

  • None of Heron Therapeutics's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Postoperative Pain is the condition Heron Therapeutics studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Postoperative Pain trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Heron Therapeutics pipeline card: 23 registered trials from official public datasets.Report a data error.