Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01662401 · ClinicalTrials.gov registry record · Phase 2

Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic

A Phase 2 study of Postoperative Pain, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

Completed
Registry status
Phase 2
Development phase
66
Enrollment target
1
Study location

NCT01662401: Completed Phase 2 study of Postoperative Pain, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

NCT01662401 is a Phase 2 study of Postoperative Pain that has completed, run by Ann & Robert H Lurie Children's Hospital of Chicago. The registered enrollment target is 66 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01662401, a Phase 2 study of Postoperative Pain, has completed, sponsored by Ann & Robert H Lurie Children's Hospital of Chicago.

COMPLETED
Registry status
Phase 2
Development phase
66 participants
Enrollment target
1
Study location

Study Summary

After undergoing a laparoscopic appendectomy, a child may experience some degree of pain in the postoperative period. As a routine part of the procedure, surgeons inject local anesthetic where the laparoscopic ports are placed. This provides some pain relief, but most children will still require additional pain medications after surgery. The purpose of the study is to see if a combination of peripheral nerve blocks (rectus sheath and ilioinguinal nerve) will give better pain relief, decreasing pain medication requirements and increasing comfort during the postoperative period.

Primary Outcome

Compare postoperative analgesic requirements during the first 48 hours in children undergoing ultrasound-guided (US) rectus sheath and ilioinguinal/iliohypogastric nerve blocks compared with those receiving traditional infiltration of local anesthetic at port sites by the surgeons for laparoscopic appendectomies.

Conditions Studied

Interventions

  • DRUG Bupivacaine

Study Locations (1)

Illinois

  • Ann & Robert H Lurie Children's Hospital of Chicago - Chicago

Trial Details

FieldValue
Enrollment Target 66 participants
Start Date 2008-05
Phase Phase 2

What the finished NCT01662401 record still lists

NCT01662401 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 66 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (71% lower).

The record links to 1 condition, with Postoperative Pain appearing as the primary indexed condition, and to 1 intervention - of which Bupivacaine is the first listed.

NCT01662401 reports a single indexed study location in Illinois.

Frequently Asked Questions

What is clinical trial NCT01662401 about?

NCT01662401 is a clinical study titled "Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic". After undergoing a laparoscopic appendectomy, a child may experience some degree of pain in the postoperative period. As a routine part of the procedure, surgeons inject local anesthetic where the laparoscopic ports are placed. This provides some pain relief, but most children will still require add...

What is the current status of trial NCT01662401?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 66 participants. The study started on 2008-05.

What conditions does trial NCT01662401 study?

This clinical trial studies the following conditions: Postoperative Pain.

What interventions are being tested in trial NCT01662401?

The interventions under investigation include: Bupivacaine (DRUG).

Who is sponsoring clinical trial NCT01662401?

This trial is sponsored by Ann & Robert H Lurie Children's Hospital of Chicago, which has 159 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01662401 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Postoperative Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01662401's enrollment target sits among peer trials

66 92nd of 120 higher than 28 of 120 other Postoperative Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02584244 · 66 participants · Phase 1

    Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers

  • NCT03067051 · 66 participants · Phase 1

    Clinical Study to Assess the Safety and Efficacy of the SpectraCure P18 System

  • NCT03754725 · 66 participants · Phase 1

    Ferritin and Iron Burden in SAH sIRB

  • NCT03875378 · 66 participants · Phase 2

    Transdermal Estrogen in Women With Anorexia Nervosa

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01662401, the US trial registry maintained by the National Library of Medicine. NCT01662401 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.