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NCT06077214 · ClinicalTrials.gov registry record · Phase 1
Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
A Phase 1 study of Postoperative Pain and Bariatric Surgery Candidate, sponsored by Virginia Commonwealth University.
- Completed
- Registry status
- Phase 1
- Development phase
- 9
- Enrollment target
- 1
- Study location
NCT06077214: Completed Phase 1 study of Postoperative Pain and Bariatric Surgery Candidate, sponsored by Virginia Commonwealth University.
NCT06077214 is a Phase 1 study of Postoperative Pain and Bariatric Surgery Candidate that has completed, run by Virginia Commonwealth University. The registered enrollment target is 9 participants, below the 232-participant average among 120 other Postoperative Pain trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06077214, a Phase 1 study of Postoperative Pain and Bariatric Surgery Candidate, has completed, sponsored by Virginia Commonwealth University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 9 participants
- Enrollment target
- 1
- Study location
Study Summary
Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however, has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain is known to last for several days in most cases and is thought to peak between 1-2 days after surgery. Therefore, the benefit of most short-acting local analgesics does not overlap with the period of most need.
Primary Outcome
Using the 10 point pain scale, determine if liposomal bupivacaine use leads to changed pain scores on post-operative day 1 compared to standard analgesics after laparoscopic sleeve gastrectomy.
Conditions Studied
Interventions
- DRUG Treatment with liposomal bupivacaine
- DRUG Treatment with standard bupivacaine
Study Locations (1)
Virginia
- Virginia Commonwealth University - Richmond
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2023-01-31 |
| Est. Completion | 2024-08-20 |
| Phase | Phase 1 |
What the finished NCT06077214 record still lists
NCT06077214 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 232-participant average among 120 other Postoperative Pain trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which Treatment with liposomal bupivacaine is the first listed.
NCT06077214 reports a single indexed study location in Virginia.
Frequently Asked Questions
What is clinical trial NCT06077214 about?
NCT06077214 is a clinical study titled "Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients". Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is...
What is the current status of trial NCT06077214?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2023-01-31. Estimated completion is 2024-08-20.
What conditions does trial NCT06077214 study?
This clinical trial studies the following conditions: Postoperative Pain, Bariatric Surgery Candidate.
What interventions are being tested in trial NCT06077214?
The interventions under investigation include: Treatment with liposomal bupivacaine (DRUG), Treatment with standard bupivacaine (DRUG).
Who is sponsoring clinical trial NCT06077214?
This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06077214 being conducted?
This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postoperative Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06077214's enrollment target sits among peer trials
9 121st of 120 the lowest of 120 other Postoperative Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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