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NCT06077214 · ClinicalTrials.gov registry record · Phase 1

Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients

A Phase 1 study of Post Operative Pain and Bariatric Surgery Candidate, sponsored by Virginia Commonwealth University.

Completed
Registry status
Phase 1
Development phase
9
Enrollment target
1
Study location

NCT06077214 is a Phase 1 study of Post Operative Pain and Bariatric Surgery Candidate that has completed, run by Virginia Commonwealth University. The registered enrollment target is 9 participants, below the 236-participant average among 56 other Post Operative Pain trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06077214, a Phase 1 study of Post Operative Pain and Bariatric Surgery Candidate, has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
Phase 1
Development phase
9 participants
Enrollment target
1
Study location

Study Summary

Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is up to 6 hours. The liposomal formulation of bupivacaine, however, has a length of therapeutic effect of up to 72 hours. Typical post-operative incisional pain is known to last for several days in most cases and is thought to peak between 1-2 days after surgery. Therefore, the benefit of most short-acting local analgesics does not overlap with the period of most need.

Interventions

  • DRUG Treatment with liposomal bupivacaine
  • DRUG Treatment with standard bupivacaine

Study Locations (1)

Virginia

  • Virginia Commonwealth University - Richmond

Trial Details

FieldValue
Enrollment Target 9 participants
Start Date 2023-01-31
Est. Completion 2024-08-20
Phase Phase 1

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT06077214

The ClinicalTrials.gov registry entry for NCT06077214 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 9 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 236-participant average among 56 other Post Operative Pain trials with a reported enrollment target (96% lower). The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Post Operative Pain appearing as the primary indexed condition, and to 2 interventions - of which Treatment with liposomal bupivacaine is the first listed.

NCT06077214 reports 1 study location spanning 1 distinct geographic area - top geographies include Virginia.

Frequently Asked Questions

What is clinical trial NCT06077214 about?

NCT06077214 is a clinical study titled "Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients". Liposomal bupivacaine (trade name Exparel) is a local analgesic that is designed to produce more long-term pain control. Bupivacaine, a widely used local analgesic, is stored within liposomes, which break down in soft tissue over time. Typical length of therapeutic effect for standard bupivacaine is...

What is the current status of trial NCT06077214?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 9 participants. The study started on 2023-01-31. Estimated completion is 2024-08-20.

What conditions does trial NCT06077214 study?

This clinical trial studies the following conditions: Post Operative Pain, Bariatric Surgery Candidate.

What interventions are being tested in trial NCT06077214?

The interventions under investigation include: Treatment with liposomal bupivacaine (DRUG), Treatment with standard bupivacaine (DRUG).

Who is sponsoring clinical trial NCT06077214?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06077214 being conducted?

This trial has 1 study location across Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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